Health
Matters Arising: Blood Transfusion Services in Nigeria
By Saifullahi Attahir
I’m sure once in your life time have experienced or had one of your acquittances received a unit of blood. But have we ever gave a second thought about how this integral part of healthcare system in Nigeria is managed? In this article, I would give the reader a glimpse into this sector due to it’s importance, and some comparison of how it’s manage in other advanced countries.
Blood transfusion was a century old medical practice developed around 1900 by a scientist called Carl landstener, despite several attempts by contemporary scientists before him to devise a means to replace loss of blood encountered by patients either during surgical operations, accidents, or child birth.
Landstener was able to perpect the art of blood transfusion through discovery of major blood groups (ABO, and Rhesus) that played role in matching donor and recipients. Since then, there was continued effort toward safe blood transfusion services across the globe which massively lead to the decline in mortality rate associated with decrease blood supply in the body.
In Nigeria, blood transfusion services was practiced since the colonial-post colonial period mostly starting in Lagos and major urban centres. The major breakthrough was when the National blood transfusion services was established in 2005 during President Obasanjo. The National Health act of 2014 lead to the passage of National blood service Agency bill in 29th /July/ 2021.
According to the NBSA (www.nbsc.gov.ng) site, there was 17 voluntary blood donation centers across the 6 geopolitical zones of Nigeria including separate centers in Federal Capital Abuja, and other centers within the Arm Forces/ Military hospitals. National blood donation day is celebrated every 8th of December, and World safe donation day celebrated every 14th, June.
Nigeria has a population of over 200 million people, and without saying, our demand for blood donation was staggering looking at the number of road traffic accidents, obstetrics patients, major surgical procedures, under 5 years malarial and Schistosomial infections. This is apart from anaemic conditions due to malnutrition (Iron deficiency), other tropical diseases, Chronic Kidney Diseases, abnormal menstruation, and burns.
With all the above mention reasons, our data regarding blood transfusion services was reprehensible.
Several factors have lead to that including community neglect, lack of government intervention, lack of standard private practices, cultural influences, poor funding, and the Almighty mismanagement of resources.
About 1,230, 000 (one million, two hundred and thirty thousand) units/pints of blood are collected annually across Nigeria healthcare facilities, but unfortunately about 90% of this donations are paid commercials. Only 25,000 units are donated by volunteers that are made available to 3,400 hospitals urgent request! This simply shows that less than 5% of blood donation in Nigeria is voluntary.
Let me highlight four different forms of donations practiced worldwide;
* There was voluntary donation done by individuals just for the sake of humanity with no ulterior motive.
*There was direct/replacement donation usually done by relatives of a patients that are called in times of emergency. This one is hugely practice in Nigeria to about 75% in public hospitals.
* There was paid commercial donations in which donors give blood and collect money for it. This practice in Nigeria constitute about 25% in public hospitals and about 75% in some private clinics. This practice carried the major risk of transmitting transfusion-transmitted infections like HIV, Hepatitis B, and C.
* There was the autologous transfusion in which individual give his own blood prior to some surgical operations where the blood is stored, and later transfused back to him. This procedure has the least risk of transmitting infection and eliciting blood transfusion reactions.
Among the four blood transfusion methods, the two most widely practiced in Nigeria are the replacement and the paid commercial. People only care to donate blood when they knew their relatives are in need. This practice was commoner in our society from the villages to the urban. You could donate as soon as you know it’s your parents, wife, son, sister, brother or friend. Any other person can go to hell!
The worst form of practice is the commercial one, where people either out of ignorance or artificial poverty volunteer to donate only if they are going to be paid for it. This business triggers every form of atrocities where the donors sometimes donate multiple times within a short period of time ( The standard is at least an interval of 4-6 months, depending on age, gender, and social status).
The paid donors carries the highest risk of transmitting infections and other abnormalities either to themselves or to the recipients. So this practice need to be discourage by the healthcare personnels and the Government.
As an insider, and with my little period of practice, I have come to realized some of the difficulties blood transfusion services encountered in our health care facilities.
Shortage of blood units
There was the problem of blood supply shortage, this is evident from how Doctors/Lab personnel always advised patient relatives to go home and mobilized their kinsmen when a patient was in need of blood. This happens as if it were the standard thing to do. The ideal is for a patient to be transfused blood from the pool of blood bank regardless of bringing replacement or not. But this can only happens if their was enough units stored in the blood bank, and in most cases their was non.
I have personally witnesses several cases where a patient can almost loose his/her life their donors travelling many kilometers only to be rejected due to mismatch. Imagine the money and time wasted! The blame is not on the healthcare personnel, nor on the government alone, the blame is on the system and our society at large. We are lacking altruism.
This problem can be attributed to the lack of decentralised system of blood banking we operate in Nigeria.
Nigeria has a single National blood donation system. While in places like US, procurement of blood is majorly met by volunteers, they have a pluralistic blood collection programs by ( Red cross, independent community blood centres,and hospitals).
In the US, 15 million units of blood are collected from 10 million donors annually, and only 7% are collected in hospitals, and 93% in regional centres, unlike Nigeria where most of the collection are done in hospitals.
In the US, the blood collection, processing, testing,and preservation are regulated by the FDA. They operated a sharing system where by blood units can be transferred from a region with less demand and higher collection to a region with more demand.
Blood transfusion data
Nigeria has a blood collection data problem, many hospitals especially in the rural areas can not keep the record consistently for a year. This problem can be attributed to the manual (pen and paper) system of health records we are still operating in Nigeria, which is subject to error, missing, or manipulation. Without proper blood collection data it would be difficult to alleviate problem of shortage, and implementation.
Lack of Awareness
A recent data has shown how blood donation is directly proportional to development; in developed countries, 50 units of blood are donated in every 1000 population. In developing countries, 15 units of blood are donated in every 1000 population. While in under developed countries, only 5 units of blood are donated in every 1000 population.
In under developed and developing countries, limited storage facilities, lack of incentives, malnutrition, personal wellbeing,and lack of knowledge can be a contributing factor to low turnout of voluntary blood donation. It’s more likely for a high income University graduate to donate blood voluntarily than a less educated poor labourer. The former might be healthier, more mentally stable, and more aware on the need to donate.
Expertise and Procurement Facilities
The current improvement in blood donation service especially in the tropics can be attributed to the benevolent funding by the US through USAID and President Emergency Plan For AIDS Relief (PEPFAR). Since 2000, there was continued efficiency in transfusion services in Nigeria, thanks to the aforementioned Agencies.
Despite this improvement, there was still problems of procedures, staff proficiency, specific testing,and preparation of separate blood components ( like plasma derivatives, platelets, and white blood cells).
Our screening methods are still qualitative immuno-phenotyping, we are using 4th generation ELISA ( Enzyme linked immunosorbent Assay), and no Nuclear Amplification Technique (NAT ) testing yet.
In 2018, I attended a two weeks training in Abuja organized by the University of Maryland experts under the supervision of Federal Ministry of Health (FMoH). We were trained on the standard serological techniques of Retro viral screening (RVS), Hepatitis, and VDRL. It was in preparation for a six month extensive survey we conducted across Nigeria based on the impact of HIV screening and therapy over the last three decades called Nigeria AIDS INDICATOR AND IMPACT SURVEY (NAIIS 2018). The training was an eye opener for me on the need to standardized our screening methods.
On a way forward, in order to attain the blood transfusion safety target, there is need for more voluntary donations campaign through mass media, schools, Churches, and Mosques.
Factors that prevent people from voluntary donations should be address like establishment of more independent blood donation centres, incentives, availability of storage facilities, and free donation services.
Nigeria should have a centralised registry of people with blood group O rhesus D negative, and such rare blood units should be made available across the country through a systematic sharing arrangement.
There is need for the communities and philanthropies to create more Non governmental organizations (NGOs) to address shortage of blood and to complement government efforts, as the government can not carryout the duty alone.
Saifullahi Attahir is the President of National Association of Jigawa State Medical Students (NAJIMS) National body. He wrote this piece from Federal University Dutse
Health
Over 1.5 million Nigerian Children Living With Sickle Cell Disease—Report
By Modupe Gbadeyanka
More than 1.5 million children under the age of 15 are living with sickle cell disease in Nigeria, a new international study published in The Lancet Child & Adolescent Health, one of the world’s leading medical journals, has revealed.
In the report made available to Business Post, it was disclosed that Nigeria carries the highest burden of disease globally, far exceeding other high-burden countries such as the Democratic Republic of the Congo and Ethiopia.
The findings highlight both the scale of the challenge in Nigeria and the opportunity for the country to lead Africa in tackling one of the most preventable causes of childhood illness and death.
The study shows that nearly nine million children across sub-Saharan Africa are living with sickle cell disease in 2023, including around 1.17 million infants and 2.75 million children under five, who face the highest risk of early death without treatment.
Sickle cell disease is an inherited blood disorder present at birth. With early diagnosis and access to simple, low-cost interventions such as newborn screening, penicillin prophylaxis, routine vaccinations, malaria prevention, and hydroxyurea, most complications and deaths can be prevented.
However, in Nigeria, access to these essential services remains limited. Many children are only diagnosed after severe and avoidable complications, while others are never diagnosed at all, contributing to high levels of preventable illness and early childhood deaths.
The researchers emphasise that strengthening Nigeria’s health system response will be critical. This includes expanding newborn screening programmes, improving access to essential medicines, and integrating sickle cell care into primary healthcare services.
They called for urgent and coordinated action across government, health institutions, and development partners, including expanding newborn screening programmes, improving access to essential medicines and vaccines, and embedding sickle cell care within primary healthcare services.
The researchers, led by Professor Davies Adeloye, Professor of Public Health at Teesside University, United Kingdom, and Director of the International Society of Global Health (ISoGH), also called for increased domestic investment, supported by international partnerships, as well as stronger data systems to improve surveillance and guide policy decisions.
They concluded that even modest improvements in early-life screening and treatment in high-burden countries like Nigeria could transform child survival and significantly reduce preventable deaths.
“Nigeria now stands at the centre of the global sickle cell crisis. With over 1.5 million children affected, the scale is enormous, but so is the opportunity to act. We already know what works. Newborn screening and early treatment are effective, affordable, and can be delivered through existing health systems.
“If Nigeria prioritises sickle cell disease within its national health agenda and integrates care into routine maternal and child health services, we could save hundreds of thousands of young lives and significantly reduce avoidable deaths.” Professor Adeloye noted.
It was learned that the study analysed data from 40 studies across 22 African countries to produce the most comprehensive country-level estimates of childhood sickle cell disease to date.
Health
Helical Secures $10m Funding Package for Expansion
By Dipo Olowookere
A $10 million capital has been raised by Helical to support expansion across more top-20 pharma programmes and growth of its deployed science engineering team.
The firm will also use the money to build the compounding evidence layer that improves performance across diseases, as its mission is to make every scientist able to test hypotheses at the speed of inference and to turn in-silico discovery into a reliable engine for R&D throughput.
The funding package was from redalpine, Gradient, BoxGroup, Frst and notable angels, including Aidan Gomez (CEO Cohere), Clement Delangue (CEO HuggingFace) and Mario Goetze (pro soccer player).
Helical has a product known as the virtual AI lab for pharma, an application layer that turns biological foundation models into decision-ready, reproducible in-silico discovery workflows.
The platform has two product surfaces — the Virtual Lab for biologists and translational scientists, and the Model Factory for ML engineers and data scientists — built on the same data, the same models, and the same results.
By putting both sides in the same system, Helical closes the gap between computational predictions and biological decision-making, so teams that traditionally worked in silos can collaborate on the same evidence.
Helical was founded in early 2024. It was created by three school friends who took different paths to the same problem.
Rick Schneider built tech at Amazon and later helped the German enterprise Celonis scale in France and Japan. Maxime Allard led data science teams at IBM before pursuing a PhD focused on reinforcement learning and robotics. Mathieu Klop became a cardiologist and genomics researcher.
When bio foundation models emerged, the trio saw the chance to build the missing application layer that would let pharma teams move from model experimentation to reproducible, production discovery.
“The models alone don’t discover drugs. The system does. Pharma teams need a system that turns foundation models into workflows scientists can run, validate, and defend.
“We built Helical to make in-silico science reproducible at pharma scale, so teams can go from hypothesis to decision in days instead of months,” the co-founder of Helical, Mr Rick Schneider, said.
“We are at a unique point in time where biological foundation models and general language reasoning models are converging.
“We backed Helical because we strongly believe they have what it takes to build the pharma AI orchestration platform that will drive this transition from siloed AI models to integrated virtual AI labs,” the General Partner at redalpine, Mr Daniel Graf, stated.
Health
NARD Suspends Indefinite Strike, Gives FG Fresh Two-Week Ultimatum
By Adedapo Adesanya
The Nigerian Association of Resident Doctors (NARD) has suspended its planned nationwide indefinite strike, granting the federal government a two-week ultimatum to address lingering welfare issues affecting resident doctors across the country.
The decision was taken after an emergency meeting of the association’s National Executive Council on Tuesday, where members reviewed assurances from government representatives and resolved to give dialogue another chance.
NARD said the suspension was informed by “progress made” in negotiations, particularly commitments on the prompt payment of salary arrears, hazard allowances, and steps toward resolving issues surrounding the Medical Residency Training Fund.
The association did not declare a full resolution of the dispute. It noted that the government had shown “renewed willingness” to address the concerns that triggered the strike threat.
The association noted that while these engagements signalled a willingness by the government to resolve the dispute, several critical issues remain outstanding, particularly the delayed payment of promotion arrears, salary arrears, the 2026 Medical Residency Training Fund (MRTF), and the backlog of 19 months’ professional allowance arrears owed to resident doctors.
It also expressed concern over the Federal Government’s decision to halt the implementation of the reviewed PAT, which had earlier triggered widespread dissatisfaction among its members and raised fears of disruption to healthcare services nationwide.
Despite these unresolved issues, NARD said it opted to suspend the strike as a demonstration of goodwill and commitment to ongoing dialogue, while giving the government a two-week window to take concrete, measurable and verifiable steps to meet its demands.
The association insisted on the immediate reversal of the decision affecting the PAT, payment of all outstanding arrears, prompt disbursement of the MRTF, and full settlement of the accumulated professional allowance backlog.
It warned that it would reconvene at the expiration of the ultimatum to assess the level of compliance and determine its next course of action, adding that failure by the government to meet its demands within the stipulated timeframe would result in the resumption of the suspended strike without further notice.
NARD also called on its members nationwide to remain calm, united and resolute, while urging the Federal Government to act swiftly to prevent a potential crisis in the health sector.
The association further appreciated the interventions of the Vice President and other stakeholders, expressing hope that their involvement would lead to the timely resolution of the dispute and help sustain healthcare delivery across the country.
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