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Peptides For Post-Surgical Healing After Rhinoplasty

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Peptides

While rhinoplasty procedures vary in complexity and expected recovery times, everyone wants to heal faster and minimise downtime after the procedure. The success of the procedure to reduce pore size will not only depend on the skill of the surgeon but also the patient’s ability to heal properly.

In the past few years, a group of molecules, known as peptides, have increasingly gained significant attention in the medical field for their incredible potential in bolstering the healing process. Simply put, they are a group of naturally occurring or synthetic amino acids that have been shown to optimise healing and recovery times.

Let’s take a deeper look at peptides, how they work, their benefits, and how they can be used in post-surgical recovery after rhinoplasty.

How Peptides Enhance Healing

Before discussing the role of peptides in rhinoplasty healing, it’s vital to understand the healing process following a rhinoplasty procedure. Rhinoplasty typically involves the manipulation of nasal tissues, which includes cartilage, skin, and bone. Once the procedure is complete, the body will naturally undergo a sequence of healing events:

Inflammation – The body will first respond to the surgical trauma by triggering an inflammatory response. This is essential for clearing away any damaged tissue to start the healing process.

Proliferation – The body then starts to produce new blood vessels and initiates the formation of granulation tissue. During this stage, collagen production will increase to help rebuild the damaged tissue.

Remodeling – The final stage entails remodeling the newly formed tissue, including collagen. The scar tissue will gradually mature and gain strength.

The quality of healing will have a direct impact on the functional and aesthetic outcome of the rhinoplasty procedure. Improper or inadequate healing may lead to complications like poor nasal shape, scarring, and even breathing difficulties. This is where peptides come in.

Peptides mainly serve as signaling molecules, orchestrating a number of biological processes needed for healing and recovery. They do this by influencing various biological actors, including cytokines, growth factors, and immune cells. For instance, growth factors are needed for cell differentiation and cell proliferation, which are critical to tissue regeneration and wound healing.

Besides this, they influence cytokines, which play a critical role in regulating inflammation. Peptides such as TB-500 and BPC-157 can help control pain and inflammation associated with rhinoplasty by regulating the production of cytokines. They also influence immune system cells, which are responsible for not only protecting the body from infection but also facilitating tissue repair.

According to peptidesireland.com, some peptides have been shown to influence protein synthesis and the metabolism of fat, both of which have a vital impact on post-rhinoplasty recovery. By enhancing protein synthesis, peptides help with the repair of damaged tissues, and by optimising fat metabolism, they help with the overall healing and energy balance.

Benefits of Using Peptides for Healing

Using peptides for tissue repair has several potential benefits

Faster healing: Peptides can quicken the healing process, essentially shortening the recovery time from the rhinoplasty procedure. Faster healing means less discomfort, less downtime, and a faster return to normalcy.

Less pain and inflammation: Since peptides are naturally occurring in the body, they are usually well-tolerated with minimal side effects. While each peptide has its unique benefits, many will have anti-inflammatory properties, which can help alleviate pain associated with surgical procedures.

Antimicrobial properties: Peptides with antimicrobial properties, like LL-37, can help lower the risk of postoperative infections, which is a common concern following surgery.

Improved Angiogenesis: Peptides such as fibroblast growth factor (FGF) and vascular endothelial growth factor (VEGF) help promote the formation of new blood vessels. They can help improve blood flow to the site of the wound, making sure there’s enough supply of oxygen and nutrients, which is vital for tissue healing.

Clinical Applications of Peptides in Rhinoplasty Healing

Although research is still ongoing when it comes to the application of peptides to heal rhinoplasty surgery, there are a few promising developments:

Topical peptide formulas: Topical peptide formulations may be used on the incision site to help stimulate the production of collagen and reduce scarring. The formulations are usually applied during the postoperative care period.

Injectable peptides: Some peptides are administered via injections to help target specific areas of the nose that might require additional healing support. This approach will essentially allow for more precise and tailored treatment.

Oral supplements: For some cases, oral supplements that contain peptides may be recommended to help promote overall healing from within.

Risks and Challenges of Using Peptides

While peptides offer great promise in enhancing rhinoplasty healing, there are several challenges to address. For starters, the efficacy and safety of certain peptides for postoperative care still need further investigation, and patient-specific elements should be considered in treatment plans.

As for the potential side effects, some patients may experience nausea, headache, or allergic reactions following peptide administration. These side effects will vary greatly from patient to patient and will be dependent on several factors, including the kind of peptide used, the amount of dose administered, and the overall health of the patient.

It’s also worth noting that while peptides are legal in many jurisdictions, some are considered performance-enhancement substances, and are therefore prohibited in certain sports. The potential misuse of peptides in industries such as bodybuilding and athletics also raises safety and ethical concerns.

Final Thoughts

The use of peptides to help with healing after rhinoplasty presents an exciting frontier in cosmetic surgery. By enhancing quality healing, peptides have the potential to lead to better functional and aesthetic outcomes.

Nonetheless, it’s still important to note that the field is still evolving, and further clinical research is needed to establish the safety and efficacy of certain peptide treatments.

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Mums Feel Warmth Initiative Raises Postpartum Depression Awareness

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Mums Feel Warmth Postpartum Depression

By Modupe Gbadeyanka

A transformative webinar to raise awareness on postpartum depression (PPD) by nursing mothers has been organised by MSc Media and Communication students from the School of Media and Communications of the Pan-Atlantic University.

The programme titled Beyond Baby Blues: Understanding and Overcoming Postpartum Depression was held on January 7, 2025.

It was put together by the students under the Mums Feel Warmth initiative, with experts in the field invited to speak on the matter aimed at empowering mothers and fostering a sense of reassurance.

The webinar was to highlight the journey through postpartum depression, offering a message of hope, resilience, and the importance of mental health support for mothers everywhere.

One of the speakers, Dr Laja Odunuga, who is the Care Coordinator for AVON HMO, explained the difference between the common “baby blues” and the more severe, long-lasting PPD.

The discussion highlighted how PPD can manifest not just as sadness but through severe fatigue, disconnection from the newborn, and loss of interest in activities, which can last well beyond the typical two-week period associated with baby blues.

Another expert, Ms Otomfon Ibanga, the Assistant Lead Nurse for Q-Life Family Clinic, emphasised the role of support systems, urging families and friends to be vigilant for signs of PPD and to provide a nurturing environment.

She also discussed prevention strategies, including prenatal planning for support structures and post-delivery management through therapy or medication.

On his part, Dr Chimaraoke Obialo, who is the Medical Director of Life Amada Health Consultancy, addressed the stigma surrounding PPD, advocating for education to transform societal perceptions from judgement to support.

The webinar underscored the need for community involvement, not just in recognising symptoms but in actively participating in the healing process by offering emotional and practical support.

The Mums Feel Warmth webinar was more than just an educational session; it was a call to action for society to embrace and support new mothers dealing with PPD.

By fostering open conversations and providing platforms for sharing experiences, Mums Feel Warmth continues to lead the charge against the stigma of PPD.

The commitment shown by the panellists and attendees alike promises a future where every mother has access to the understanding and care needed to navigate through the complexities of postpartum depression, ensuring that the joy of motherhood is not overshadowed by mental health challenges.

Mums Feel Warmth, with its core values of empathy, compassion, hope, community, and education, speaks to the Sustainable Development Goal 3, advocating for good health and well-being.

The initiative is breaking the silence around PPD, a condition that can significantly impact new mothers in the critical period following childbirth.

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NCDC Monitors HMPV Situation, Affirms Nigeria at Moderate Risk

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By Adedapo Adesanya

The Nigeria Centre for Disease Control (NCDC) says the country is at “moderate” risk for Human Metapneumovirus (HMPV), a virus that leads to an upper respiratory tract infection with symptoms like cough, fever, and nasal congestion.

In a public health advisory, the Nigerian health agency said the federal government is closely monitoring the outbreak of the virus and is taking safety measures to “strengthen the country’s preparedness and response capacity”.

Recent reports indicate a significant rise in HMPV cases in China, as well as increased respiratory infections linked to HMPV in countries such as the United Kingdom (UK), France, and Germany, particularly during the winter season.

The NCDC said it conducted a risk assessment for the HMPV in collaboration with the Federal Ministry of Health and partners such as the World Health Organization (WHO), the US Centres for Disease Control and Prevention (USCDC), and the UK Health Security Agency (UKHSA).

“The assessment classified the risk of HMPV for Nigeria as moderate. This evaluation will inform and guide preparedness efforts, decision-making, and response strategies to mitigate potential impacts,” the advisory said.

It said the NCDC is working to give Nigerians “timely, accurate information and guidance to keep the Nigerian public informed and prepared”.

NCDC noted that it “in collaboration with Port Health Authorities, is taking proactive steps to ensure robust preparedness at all international points of entry (PoEs) in response to the dynamic risk assessment for Human Metapneumovirus (HMPV).

“These measures are designed to mitigate the potential risk of HMPV transmission through international travel.”

HMPV was first identified in the Netherlands in 2001 and the virus spreads through direct contact between people or when someone touches surfaces contaminated with it.

Children under two are most vulnerable to the virus alongside those with weakened immune systems such as the elderly and those with advanced cancer, according to medical experts.

There have also been worries that this could be like COVID-19, but experts have eased the fear as they are not similar because pandemics are typically caused by novel pathogens, which is not the case for HMPV.

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Digitising Healthcare With Local Realities in Mind: Shaping The Future of Healthcare in Africa

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eHealth Africa (eHA) has urged governments and stakeholders to explore the critical factors beyond technology that are essential for the deployment of digital health solutions for the long-term success of public health systems across Africa. Data-backed interventions will help streamline operations and enable the formulation of interventions that appreciate the cultural norms when addressing the immediate needs of different communities within the region.

Speaking during a panel session at the Global Digital Health Forum 2024 in Nairobi, eHealth Africa’s Executive Director Atef Fawaz emphasised the importance of integrating technology with local cultures and addressing community-specific needs. “Understanding the unique healthcare challenges in each country allows us to deploy tech solutions that truly make an impact.”For instance, eHealth Africa successfully delivered over 5.8 million vaccines (5,801,209) to 351 primary healthcare facilities across states in Nigeria which was made possible through the deployment of the innovative Logistics Management Information System (LoMIS) application.

“The system significantly improved the availability of vaccines for Routine Immunisation (RI), ensuring timely and efficient distribution while eliminating stockouts at primary healthcare facilities. This intervention highlights our commitment to strengthening immunisation programs and enhancing healthcare delivery at the grassroots level,” he said.

In his contribution, Abdulhamid Yahaya, the Deputy Director of Global Health Informatics highlighted the need to understand the local cultural, social, and regulatory landscape to build solutions that are designed with local realities in mind.

eHealth Africa Board Member Micheline Ntiru said using technology provided stakeholders among them global health leaders, tech innovators, and development experts as well as local communities a platform to create the right solutions that work within the constraints of each community, and with the support of local leadership.

For instance, local health workers have been using mobile-based reminder systems to improve compliance and overall health outcomes while some local immunisation centres have been sending SMS reminders to parents as well as to provide educational messages about the diseases they protect against. Mobile phones, now available in nearly 80 per cent of African homes, can also be used during emergencies to dispatch mass announcements about satellite clinic locations and schedules.

According to the World Health Organisation, increased use of the Internet, email, social networking sites and availability of mobile phones facilitates the deployment of eHealth solutions, applications and services towards the improvement of national health systems. The use of technological eHealth solutions could also be used to encourage positive lifestyle changes to prevent and control common diseases.

The panel moderated by Ota Akhigbe, Director of Partnerships and Programs comprised of  Ms Ntiru (Delta40 ventures), Mr Yahaya (eHealth Africa), Chief Impact Officer at Tiko – Serah Malaba, Dr Olamide Okulaja (Maisha Meds), Audere Chief Executive Officer Dr Dino Rech, and  Rachel Alladian from Jacaranda. They discussed how strategic partnerships, regulatory compliance, and a deep understanding of local contexts are crucial for driving digital health innovations that can succeed in diverse regions.

The GDHF forum was attended by health scholars, researchers, and representatives from the Ministry of Health in Ethiopia, Tanzania, Kenya, Malaysia, Somalia and Sri Lanka as well as representatives from the World Bank, medicine manufacturers, technology vendors, UN agencies among others.

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