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Takeda Okays Phase 3 Trial of ALUNBRIG

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By Dipo Olowookere

Takeda Pharmaceutical Company Limited has disclosed that the global, randomized, Phase 3 ALTA-1L (ALK in Lung Cancer Trial of AP26113 in 1st Line) trial met its primary endpoint at the first pre-specified interim analysis, with ALUNBRIG (brigatinib) demonstrating a statistically significant improvement in progression-free survival (PFS) compared to crizotinib in adults with anaplastic lymphoma kinase-positive (ALK+) locally advanced or metastatic non-small cell lung cancer (NSCLC) who had not received a prior ALK inhibitor.

The trial was designed to assess the efficacy and safety of ALUNBRIG in comparison to crizotinib based on evaluation of the primary endpoint of PFS, or length of time from the start of treatment that a patient lives without the disease getting worse. ALUNBRIG is currently not approved as frontline therapy.

“This represents a major milestone for the ALUNBRIG program. Our goal with ALUNBRIG is to improve the lives of patients with ALK+ NSCLC by furthering the available therapeutic options,” said Jesús Gomez-Navarro, M.D., Vice President, Head of Oncology Clinical Research and Development, Takeda. “We are encouraged by the data, which demonstrated a statistically significant improvement in progression-free survival versus crizotinib in patients with ALK+ advanced NSCLC, and look forward to beginning discussions with regulatory authorities as we seek to expand ALUNBRIG’s indication into the frontline setting.”

The safety profile associated with ALUNBRIG from the ALTA-1L trial was generally consistent with the existing prescribing information, with no new safety concerns.

The results from this interim analysis will be submitted for presentation at an upcoming medical meeting.

Dipo Olowookere is a journalist based in Nigeria that has passion for reporting business news stories. At his leisure time, he watches football and supports 3SC of Ibadan. Mr Olowookere can be reached via dipo.olowookere@businesspost.ng

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Dangote’s Foundation Gives Ambulance to Mainland Hospital Yaba

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Mainland Hospital Yaba Ambulance Dangote

By Modupe Gbadeyanka

An ambulance has been donated to the Mainland Hospital Yaba, Lagos, by the Aliko Dangote Foundation (ADF), the first the health facility was getting in the past decade.

The chief medical director of the organisation, Mr Adejumo Adedeji Olusola, while receiving the item last Friday, emphasized how crucial the donation was, describing patient mobility as a longstanding challenge.

“Today we received an ambulance from Aliko Dangote Foundation to support our response activities in Lagos. Aliko Dangote Foundation has taken care of our biggest headache; in fact, it is a game changer for us, so we can do a lot of things now that we can’t do before,” the medical practitioner stated.

He further acknowledged the impact of private sector support, particularly expressing appreciation to Mr Aliko Dangote for addressing a decade-long need.

“We are really grateful, and our sincere gratitude goes to Mr Aliko Dangote. We lacked an ambulance for about 10 years, but now we have one we can boast of thanks to Mr Aliko Dangote. Thank you very much,” he said.

In his remarks, the Director of Health and Nutrition for the ADF, Mr Francis Aminu, reiterated the foundation’s unwavering dedication to improving the lives of Nigerians, particularly in the health sector.

He opined that the ambulance would bolster Mainland Hospital Yaba’s capacity to manage infectious disease outbreaks and enhance emergency response.

“We are happy to help. The foundation is there to assist, especially in areas of health. They say health is wealth, so the foundation is there to fill the gaps found and through this donation initiative, this is us (ADF) showing our commitment to ensuring those needs are met.

“What we do at ADF isn’t just charity, it’s a duty. We believe that every Nigerian life is valuable, and health is the foundation on which all other aspirations are built; no Nigerian should be left behind due to a lack of access to essential health resources.

“This isn’t a one-time effort; we are committed to building systems that last, ones that Nigerians can rely on even in the toughest of times,” the remarked.

The ambulance is expected to serve as a game changer, enabling swift mobility for critical cases and improving the hospital’s overall efficiency in disease outbreak responses.

ADF has long been at the forefront of major health interventions in Nigeria, from combating malnutrition and polio to supporting disease control during pandemics. This gesture to Mainland Hospital is one of many strategic moves reflecting its broader mission to strengthen Nigeria’s healthcare infrastructure.

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Mental Health in Nigeria, is it Recognised?

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Timi Olubiyi Mental Health

By Timi Olubiyi, PhD

It is safe to say Nigeria’s economy has undergone transformations in recent times, characterised by overambitious reforms aimed at stabilising the macroeconomic environment.

However, these changes have also introduced challenges that directly affect the daily lives of Nigerians.

As of March 2025, Nigeria’s annual inflation rate rose again to 24.23%, up from 23.18% in February 2025, even though it had reached a high of 34.8% in December 2024. Higher food prices and the cost of living primarily contribute to this increase.

Additionally, petrol price has experienced a 488% increase from N175 in May 2023 at the resumption of the current administration to N1,030 in October 2024, even though it currently trades around N950.

The removal of fuel subsidies and the devaluation of the naira have further exacerbated inflationary pressures, leading to increased costs for imported goods and services.​ The removal of the fuel subsidies has significantly increased operational expenses for businesses, leading to higher prices for goods and services. This situation has led to significant hardship, and it has also made it difficult for many Nigerians to sustain livelihoods, especially those in low-income brackets.

No doubt, the economic challenges continue to have profound effects on mental health, livelihood and well-being. This is in a country where the cost of medicines, in some cases, has risen significantly, with a more than tenfold increase in price.

Mental health is a big issue in all of this, and it is largely disregarded—it is the core of how we experience and navigate our daily activities. Whether in the workplace, market, family, or among friends, the current economic woes do affect our emotional and psychological well-being regardless.

Mental health issues can affect anyone regardless of your age, gender, geography, income, social status, race, ethnicity, or religion. Mental illnesses are health disorders characterised by changes in feelings, thinking, or behaviour, or a combination thereof.

Mental health issues may be linked to discomfort and/or difficulties in professional, social, or family functioning. It determines the quality of overall health, relationships, decisions, security and well-being. The influence of mental health has become undeniably clear in the realms of business, family, and social life in Nigeria.

In Lagos State, for instance, it is a high-pressured environment; many spend long hours to get to work, employers give unrealistic expectations, and job insecurity can create chronic stress, mental health issues and physical illness.

Many can still remember the recent occurrence where some employees in Lagos State who work on the island and live on the mainland of the state experienced long hours in traffic that kept some in Lagos Island at 2am in traffic due to road closures and road maintenance. Such employees are more likely to experience depression or burnout, which can make them underperform. It may even lead to having some chronic issues around their mental health, even though many hardly accept this fact.

In fact, the World Health Organization estimates that depression and anxiety alone cost the global economy a lot. For employees, records have shown that symptoms of mental illness may include difficulty concentrating, absenteeism, emotional exhaustion, or a lack of motivation to even socialize. For entrepreneurs and executives, the stakes are different but equally significant.

The loneliness at the top, coupled with financial and operational pressures, can lead to decision fatigue and emotional instability.

At home, mental health is deeply integrated in attitudes of married couples and families it often leads to strain in communication and tension in the household, and it can lead to emotional withdrawal or even manifest in conflicts.

The high rate of unemployment and joblessness in our country can also contribute to mental health issues in households. However, a parent’s mental health condition significantly shapes the emotional environment in the home and how children grow up.

Humans are social beings, and decent work can contribute to recovery, even though in Nigeria, like many parts in Africa, we fail to recognise the significant impact of mental health on businesses, families and social lives.

More so our need for connection, acceptance, and belonging is deeply rooted in our psychological recognition that mental health is real. Mental health shapes how we interact with others, and our social interactions, in turn, influence our mental health.

So, when mental health is compromised, therefore the ability to form and maintain healthy relationships are also compromised. Depression can result in social withdrawal, anxiety can lead someone to avoid gatherings or become overly self-conscious, and trauma can lead to difficulty trusting others. As a result, people often find themselves isolated during their most vulnerable moments—when support is most needed.

In all, a supportive family can be a powerful buffer against mental health struggles.Therefore, in my opinion, it is crucial to normalise mental health discussions in workplaces, families, and friendship groups to promote understanding and encourage self-care.

In the professional world, success is often measured by tangible outcomes: revenue, promotions, deadlines met, and goals achieved. But beneath the surface of performance metrics lies a crucial, often invisible factor—mental health. Because we are in a world that often prioritises and celebrates output over well-being, re-centering mental health is not just an act of care—it is more than important in the current dispensation for more work-life balance, longevity and a successful life. Good luck!

How may you obtain advice or further information on the article? 

Dr Timi Olubiyi is an entrepreneurship and business management expert with a PhD in Business Administration from Babcock University, Nigeria. He is a prolific investment coach, author, seasoned scholar, chartered member of the Chartered Institute for Securities and Investment (CISI), and a Securities and Exchange Commission (SEC)-registered capital market operator. He can be reached on the Twitter handle @drtimiolubiyi and via email: drtimiolubiyi@gmail.com, for any questions, reactions, and comments.

The opinions expressed in this article are those of the author, Dr Timi Olubiyi, and do not necessarily reflect the opinions of others.

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IHS Nigeria Accesses Operational Status of Donated Oxygen Plant at OOUTH

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IHS Nigeria Oxygen Plant at OOUTH

By Modupe Gbadeyanka

A team from IHS Nigeria recently visited the Olabisi Onabanjo University Teaching Hospital (OOUTH) in Sagamu, Ogun State, to evaluate the operational status and impact of the oxygen plant it donated to the health facility in 2023.

The subsidiary of IHS Holding Limited donated the life-saving oxygen plant to OOUTH in collaboration with the United Nations Children’s Fund (UNICEF) and the Canadian government as part of a collaborative health infrastructure intervention initiative.

It was part of IHS Nigeria’s commitment to improving Nigeria’s healthcare system through sustainable, impactful initiatives is designed to serve not only the teaching hospital, but also other health facilities in the region.

The oxygen plant is equipped with 50 units of 6-cubic-meter cylinders and 150 units of 3 cubic meter cylinders that currently supplies critical departments across the teaching hospital including Anesthesia, the ICU, Pediatrics, Accident and Emergency, Labour, and Surgery departments.

The hospital management acknowledged the difference the plant has made in ensuring prompt availability of oxygen even for patients who are unable to pay and in improving the medical outcomes for many patients who need oxygen as part of their management.

Accompanying the team on the visit was the Commissioner for Environment in Ogun State, Mr Ola Oresanya, who was invited to witness the outcome of the partnership and its alignment with the state’s public health and environmental objectives.

He lauded the initiative for its timeliness and noted that the impact of the donation could not be easily quantified in terms of its relevance to healthcare delivery and its sustainable energy and environmental management which supports the state government’s vision for a healthier and more resilient Ogun State.

Speaking during the visit, the Director for Sustainability at IHS Nigeria, Titilope Oguntuga, said, “As a responsible organization, we find ways to impact communities in the markets we serve. In demonstrating our commitment, we also ensure that our investments are running smoothly, which is why we visited OOUTH.

“This is the first institution we donated an oxygen plant to and is also the first we are visiting to assess its impact and operational status.

“We are humbled by the acknowledgment and testimonies from the OOUTH management. This increases our resolve to continue to create meaningful and sustainable impact through infrastructure that saves lives and strengthens communities.”

Also, the Chief of Field Office for UNICEF, Celine Lafoucriere, said, “We cannot overemphasise the power of partnerships in achieving health equity. This is what building resilience in health systems entails: combining expertise, funding, and a shared goal.”

The Chairman of Medical Advisory Committee, Dr Oluseun Adeko, who represented the Chief Medical Director of OOUTH, said, “This oxygen plant has not only enhanced our ability to manage emergencies and respiratory cases, but it has also saved lives beyond our hospital, as it serves as a source of oxygen for other hospitals. We deeply appreciate IHS Nigeria and UNICEF for their foresight and generosity.”

IHS Holding Limited is one of the largest independent owners, operators, and developers of shared communications infrastructure in the world by tower count.

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