Media OutReach
Case Study Highlights INDIBA 448 kHz Radiofrequency’s Role in Visceral Fat Reduction and Prevention of Fat Accumulation
Revolutionizing Fat Reduction and Prevention
Unlike traditional fat-reduction treatments such as liposuction, cryolipolysis, and laser lipolysis—which focus on eliminating existing fat—INDIBA’s 448 kHz radiofrequency technology takes a proactive approach by targeting fat accumulation at its source. Instead of merely removing fat cells, INDIBA actively interferes with their formation at a cellular level, offering a scientifically backed, non-invasive solution for long-term fat management.
Visceral fat, the type that accumulates around internal organs, is known to be a significant contributor to serious health conditions, including cardiovascular disease, type 2 diabetes, and metabolic syndrome. While reducing visceral fat has traditionally been difficult without invasive intervention, INDIBA’s advanced radiofrequency technology provides a safe and effective alternative.
Case Study Conducted at Onomura Clinic, Tokyo
In a case study conducted at Onomura Clinic, Tokyo, Japan, the effects of INDIBA 448 kHz radiofrequency were evaluated on three individuals with varying levels of visceral fat accumulation.
Key Findings:
- Patient 1: A 36-year-old female underwent five 20-minute sessions, achieving a 45% reduction in visceral fat, with an additional 2 kg weight loss.
- Patient 2: A 42-year-old female completed eight sessions, resulting in a 38.3% reduction in visceral fat and a 2.9 kg weight loss.
- Patient 3: A 50-year-old male received thirteen sessions over 17 days, achieving a 21% reduction in visceral fat and a 3.3 kg weight loss.
These results were verified through CT scan and weight measurement, demonstrating significant reductions in visceral fat deposits following treatment.
Scientifically Validated Anti-Adipogenic Effects
In addition to these clinical outcomes, scientific research published in Molecular Medicine Reports (2016) further supports INDIBA’s anti-adipogenic effects. The study, conducted by Dr. Hernández-Bule, Dr. Alejandro Úbeda, and colleagues, demonstrated that subthermal (non-heated) radiofrequency exposure at 448 kHz significantly inhibits the differentiation of human mesenchymal stem cells (hMSCs) into adipocytes—the cells responsible for fat storage.
- INDIBA’s technology has been shown to reduce fat storage by up to 61%—before it even has a chance to form. That means you can achieve a slimmer, more contoured body without the need for invasive procedures.
- INDIBA’s technology targets the key gene responsible for fat storage, effectively ‘switching it off’ and preventing fat from forming in the first place.
- Activation of the MEK1/2 pathway, which blocks a key process needed for fat cells to fully form, making it harder for the body to store fat.
This mechanism confirms that INDIBA not only reduces existing fat but also prevents the formation of new fat cells, offering a comprehensive solution to fat management and body contouring.
How INDIBA 448 kHz Works: A Non-Invasive Approach to Fat Reduction and Prevention
INDIBA’s radiofrequency technology delivers three key physiological actions that work synergistically to reduce fat and support tissue health:
- Biostimulation – Promotes cellular metabolism and fat breakdown while enhancing tissue regeneration.
- Vascularization – Improves blood flow, aiding in detoxification and nutrient delivery to support fat metabolism.
- Hyperactivation – Accelerates metabolic activity, facilitating the body’s natural fat-reduction processes and preventing new fat accumulation.
INDIBA not only delivers longer-lasting results but also eliminates the risks of surgical procedures, such as scarring, infection, and prolonged recovery times. With zero downtime, it offers a safe and effective solution for sustainable body contouring and visceral fat reduction.
Transforming Beauty and Wellness Practices
For aesthetic doctors, beauty and wellness professionals, and medical spas, INDIBA 448 kHz represents a next-generation, evidence-based solution that aligns with the increasing demand for non-invasive, effective, and scientifically validated fat management treatments.
The ability to reduce visceral fat, prevent fat cell formation, and support skin tightening and tissue regeneration makes INDIBA a versatile treatment option. It is suitable as a standalone therapy or as an adjunctive treatment to enhance the results of other body-contouring procedures.
Looking Ahead
This research and case study reinforce INDIBA’s position as a leader in non-invasive fat management technology. As the industry moves toward more holistic and preventative health and wellness solutions, INDIBA’s 448 kHz radiofrequency stands out for its scientific validation, clinical efficacy, and commitment to safety.
For more information about INDIBA 448 kHz technology and partnership opportunities, visit www.indibasia.com.
Hashtag: #INDIBA
The issuer is solely responsible for the content of this announcement.
About INDIBA
With over 40 years of expertise in radiofrequency technology, INDIBA is a global leader in non-invasive beauty, wellness, and clinical recovery solutions. Headquartered in Barcelona, Spain, INDIBA continues to set industry standards through innovative technologies that empower healthcare professionals and improve lives worldwide. INDIBA Asia Headquarters is based in Singapore.
Available in Six Expressive Colorways, HYTE’s Latest PC Case Delivers Perfect Balance of Form and Function with Accessible Pricing
CALIFORNIA, UNITED STATES – Media OutReach Newswire – 19 December 2025 – HYTE, a leading manufacturer of cutting-edge PC components and peripherals, announces its highly anticipated X50 and X50 Air Modern Performance Cases are now available. Following its successful Computex 2025 debut, the X50 cases are meticulously designed chassis engineered with premium materials and finishes for incredible durability, while maintaining a builder-friendly experience with tool-less panels, integrated cable management, and future-proof component compatibility.
HYTE’s new X50 and X50 Air cases redefine traditional PC chassis design with fully rounded construction and built-in performance optimizations. These include a Full-Coverage Micro-Mesh front panel for low-pressure air intake, HYTE’s patent-pending Louvered Blade Ventilation on the back which reduces exhaust impedance while reinforcing rigidity, and a structural top-mounted PSU canopy enabling hassle-free cable management. Both cases feature massive 360mm radiator support on front and side, with total capacity for up-to-10 fans, including up to 3x 120mm extra-thick fans on the bottom for cold-floor GPU cooling.
Key features include:
- Premium Build Materials – 1mm-thick steel improves chassis strength and durability. Manufactured with Automotive-Grade Tooling, the X50 has 4x tighter tolerances than other PC cases, achieving its signature rounded curves
- Superior Build Experiences – The rounded design contributes to a comfortable build experience. Its tool-less front and side panels, covertly routed cable-routing channels, and spacious interiors lets anyone build in the X50 with no obstructions.
- Distinct Aesthetic Options – X50 features sweeping curved 4mm-thick laminated acoustic glass for maximum visibility and noise dampening. X50 Air uses curved Full-Coverage Micro-Mesh panel for enhanced airflow. X50 Air available in Snow White and Pitch Black; standard X50 in Snow White, Pitch Black, Wild Cherry, Taro Milk, Strawberry Milk, and Matcha Milk
WEBSITE: https://hyte.com/store/x50
Hashtag: #HYTE
The issuer is solely responsible for the content of this announcement.
ABOUT HYTE
HYTE is a lifestyle-centered brand enhancing play with innovative PC components and accessories. Designed for gaming, music, arts and entertainment, all HYTE products are rigorously researched and tested. Visit: 
http://www.hyte.com
Available in Six Expressive Colorways, HYTE’s Latest PC Case Delivers a Perfect Balance of Form and Function Through its Disciplined Multi-Dimensional Design Complete with Accessible Pricing
CALIFORNIA, UNITED STATES – Media OutReach Newswire – 19 December 2025 – HYTE, a leading manufacturer of cutting-edge PC components and peripherals, is excited to announce that its highly anticipated X50 and X50 Air Modern Performance Cases are now available. Following its successful Computex 2025 debut, the X50 cases are meticulously designed PC chassis that are engineered with premium materials and finishes that allow for incredible durability, while maintaining a builder-friendly experience with its tool-less panels, integrated cable management solutions, and future-proof component compatibility.
HYTE’s new X50 and X50 Air cases redefine traditional PC chassis design, as both cases feature a fully rounded design with several built-in performance optimizations. These include a Full-Coverage Micro-Mesh front panel for low-pressure and low-resistance air intake, HYTE’s patent-pending Louvered Blade Ventilation on the back of the case which reduces exhaust impedance while reinforcing case rigidity, and a structural top-mounted PSU canopy that lets the PSU act as an exhaust fan while opening up hassle-free cable management. Both the X50 and X50 Air feature massive 360mm radiator support on the front and side of the case, with a total capacity of up-to-10 fans, including up to 3x 120mm extra-thick fans on the case’s bottom for cold-floor cooling that keeps any GPU comfortably cool.
Other key features of the X50 and X50 Air Modern Performance Cases include:
- Premium Build Materials – Both cases use 1mm-thick steel that improves chassis strength and durability. Manufactured with Automotive-Grade Tooling, the X50 has 4x tighter tolerances than other PC cases, which allows HYTE to achieve the X50’s rounded compounded curves
- Superior Build Experiences – The X50 and X50 Air’s rounded design contributes to the ease of any build without being harsh on a builder’s hands. Its tool-less front and side panels, covertly routed cable-routing channels, and spacious interiors lets anyone build in the X50 with no obstructions.
- Distinct Aesthetic Options – The X50 comes with a sweeping curved 4mm-thick laminated acoustic glass for maximum visibility and passive noise dampening. The X50 Air swaps the glass panel with a curved Full-Coverage Micro-Mesh panel that enhances the case’s airflow capabilities. While the X50 Air only comes in Snow White and Pitch Black, the standard X50 will be available in Snow White, Pitch Black, Wild Cherry, Taro Milk, Strawberry Milk, and Matcha Milk colorways.
WEBSITE:
To know more about an X50 or an X50 Air Modern Performance Case, please visit: https://hyte.com/store/x50
Hashtag: #HYTE
The issuer is solely responsible for the content of this announcement.
ABOUT HYTE
HYTE is a lifestyle-centered brand focused on enhancing play with its fresh and innovative PC components and accessories. Designed to fuel passions in gaming, music, the arts and entertainment, all HYTE products are rigorously researched and tested before they are brought to fruition. HYTE, as a company and its products, are inspired by the needs and behaviors of its community and the many ways people play. HYTE is committed to designing products to help people experience play throughout their lifestyle, no matter what that may be. To learn more, please visit: 
http://www.hyte.com
Work-Integrated Learning Matters
Work-Integrated Learning bridges the gap between classroom theory and practical application. By immersing students in authentic work environments, internships cultivate essential skills beyond technical knowledge, including cognitive abilities such as problem-solving, affective traits like emotional intelligence, and psychomotor skills that enhance hands-on performance. Graduates who master these dimensions stand out as versatile professionals ready to contribute from day one, shaping leaders of the future who can drive innovation and growth.
The SIM60 WILL Award: Setting Graduates Apart
The SIM60 WILL Award is more than a recognition, it is a testament to resilience and excellence. Students who complete internships successfully and demonstrate perseverance in challenging situations are honoured for their commitment to growth. This award signals to employers that recipients are not only academically competent but also workplace-ready, equipped with the adaptability and grit that modern industries demand. It reinforces SIM’s mission to foster sustainable employment by preparing graduates for long-term career success.
Success Stories That Inspire
Recipients of the SIM60 WILL Award come from varied academic and personal backgrounds, yet many share a common pathway: leveraging work-integrated learning experiences to strengthen their career readiness. Several award recipients have used internships to apply classroom knowledge to real business environments, developing data dashboards, automating processes, supporting cybersecurity initiatives, and contributing to enterprise-level digital projects.
For some, these internships have served as stepping stones to contract or full-time roles in areas such as business analysis, project management and data operations. Others have progressed to subsequent placements in high growth sectors, where exposure to real world challenges has helped refine their technical skills and broaden their understanding of industry expectations.
These experiences reflect SIM’s commitment in shaping leaders of the future and fostering Sustainable Employment through Work-Integrated Learning, demonstrating how structured internships, supported by SIM’s guidance and reinforced through the WILL Award, equip learners with practical competencies and professional confidence to navigate evolving career landscapes.
Impact on Employability
Internship experience is a proven differentiator in hiring decisions. According to global employability studies, candidates with practical exposure are significantly more likely to secure roles and advance in their careers. The SIM60 WILL Award amplifies this advantage by validating the quality of a student’s internship performance. For employers, it serves as a trusted benchmark of talent. For graduates, it opens doors to opportunities that might otherwise remain out of reach, enhancing employability in a rapidly evolving economy.
Key Takeaways
The SIM60 WILL Award reflects SIM’s ongoing efforts to integrate work experience into education, supporting students in building practical skills that complement academic learning. By recognizing internship excellence, the award highlights the importance of resilience and adaptability in preparing graduates for the evolving job market.
References:
- SIM60 WILL Award/Career Service – https://www.sim.edu.sg/degrees-diplomas/life-at-sim/career-services
- Ng Jing Heng on Turning an Internship into a Career Launchpad – https://www.sim.edu.sg/articles-inspirations/ng-jing-heng-on-turning-an-internship-into-a-career-launchpad
- Chen Soon Keat’s Journey from Intern to Innovator – https://www.sim.edu.sg/articles-inspirations/chen-soon-keat-journey-from-intern-to-innovator
Hashtag: #SIMGlobalEducation #SIMGE #GlobalEducation #InternationalDegree #CareerReady #FutureSkills
The issuer is solely responsible for the content of this announcement.
About SIM Global Education
SIM Global Education (SIM GE) is a leading private education institution in Singapore and the region. We offer more than 140 academic programmes ranging from diplomas and graduate diploma programmes to bachelor’s and master’s degree programmes with some of the world’s most reputable universities from Australia, Canada, Europe, United Kingdom, and the United States. SIM GE’s cohort is made up of 16,000 full- and part-time students and adult learners, of which approximately 36% are international students hailing from over 50 countries.
SIM GE’s holistic learning approach and culturally diverse learning environment aim to equip students with knowledge, industry skills and employability competencies, as well as a global perspective to succeed as future leaders in a fast-changing, technologically driven world.
For more information on SIM Global Education, visit sim.edu.sg
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