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CK Life Sciences Establishes Sequencio Therapeutics to Advance Therapeutic Cancer Vaccines Development
The Third Pillar of a Strategic Reorganisation
This marks the third pillar of a strategic reorganisation, following transactions involving Nasdaq-listed TransCode Therapeutics (“TransCode”, “RNAZ”) and Dogwood Therapeutics (“Dogwood”, “DWTX”) completed in 2025 and 2024, respectively. Collectively, these developments are intended to accelerate R&D, enhance operational execution, and broaden capital access for pharmaceuticals and diagnostics R&D, positioning CK Life Sciences at the forefront of therapeutic cancer vaccine development.
Sequencio – A Therapeutic Cancer Vaccine R&DPlatform
Sequencio Therapeutics has been established to consolidate CK Life Sciences’ therapeutic cancer vaccine research and development portfolio under a dedicated organisation, reflecting the Company’s strategic focus on this emerging class of cancer immunotherapy. The subsidiary is focused on the development of therapeutic cancer vaccines designed to train a patient’s own immune system to achieve durable, long-term remission with a favourable safety profile, addressing key limitations of current standard-of-care therapies. The establishment of Sequencio supports a long-term vision of shifting cancer treatment paradigms from transient tumour reduction toward sustained, immune-controlled remission, with vaccine discovery and design conducted in-house and development advanced through a combination of internal capabilities and external collaborations.
Sequencio’s preclinical portfolio includes the Company’s investigational cancer vaccines targeting Trophoblast Cell Surface Antigen 2 (TROP2), which has demonstrated robust T-cell immune responses and achieved 100% tumour growth inhibition in preclinical breast and colorectal cancer mouse studies. The portfolio also includes vaccine candidates targeting PRAME (Preferentially Expressed Antigen in Melanoma), PD-L1 (programmed cell death ligand 1), B7-H3 (B7 homolog 3), and Claudin 6.
Dr Melvin Toh, Chief Scientific Officer: A Significant Milestone in Ongoing Commitment to Transforming Cancer Treatment
“The establishment of Sequencio marks a significant milestone in our ongoing commitment to transforming cancer treatment,” said Dr Melvin Toh, Chief Scientific Officer at CK Life Sciences. “By consolidating our cancer vaccine research under a dedicated entity, we are establishing a focused platform with the agility and expertise required to drive breakthrough science from the laboratory to the clinic, with the aim of delivering potential benefits to patients.”
Over the past two years, CK Life Sciences has undergone a comprehensive restructuring to maximise the potential of its R&D portfolio, with a view to attracting additional funding from investors. In 2025, the Company’s late-stage melanoma vaccine seviprotimut-L was sold to Nasdaq-listed TransCode in exchange for an equity stake in Transcode. Through the integration of seviprotimut-L into TransCode Therapeutics’ pipeline, the potential synergy between vaccine-driven immunity and RNA-based mechanisms presents an opportunity to explore new approaches to addressing treatment resistance and achieving more durable patient responses.
Separately, in 2024, CK Life Sciences completed a transaction with Dogwood Therapeutics, a Nasdaq-listed company focused on developing new medicines for pain and neuropathy, in which CK Life Sciences holds a majority stake. Dogwood is advancing Halneuron® for chemotherapy-induced neuropathic pain, which has demonstrated positive interim Phase 2b results. Dogwood has also secured a global licence to develop an intravenous formulation of SP16 for cancer-related pain.
Both Nasdaq-listed companies are led by experienced scientific and commercial teams, providing greater access to US capital markets and potential strategic partnerships to expedite development. These transactions enable CK Life Sciences’ commercial operations to provide initial and standby funding for its in-house preclinical programmes, now consolidated under Sequencio.
With Sequencio, TransCode and Dogwood, CK Life Sciences now offers an R&D platform with a diversified pipeline of early and late-stage projects targeting substantial unmet medical needs.
Mr Alan Yu, Deputy Chairman: Consider Expanding in an Innovative and Hi-tech Zone like the Northern Metropolis
“By leveraging strategic partnerships, access to public markets, and focused internal development, we are combining the agility of dedicated teams, with the resources needed to advance groundbreaking sciences,” added Mr Alan Yu, Deputy Chairman of CK Life Sciences. “We look forward to delivering these innovative therapies to the patients who need them most. As our R&D projects mature, we may need to consider expanding our R&D facilities in an innovative and hi-tech zone like that of Hong Kong’s Northern Metropolis.”
Hashtag: #CKLifeSciences #Sequencio #CancerVaccines #R&D #Pharmaceutical #Dogwood #DWTX #TransCode #RNAZ
The issuer is solely responsible for the content of this announcement.
CK Life Sciences Int’l., (Holdings) Inc.
CK Life Sciences Int’l., (Holdings) Inc. (stock code: 0775) is listed on the Stock Exchange of Hong Kong. With a mission of improving the quality of life, CK Life Sciences is engaged in healthcare research and development, with operating businesses that enable its R&D sustainability. Regarding pharmaceutical research and development, CK Life Sciences’ operations are focused on conducting research and development into cancer vaccines, RNA therapeutics and pain management solutions. CK Life Sciences is a member of the CK Hutchison Group. For additional information, please visit www.ck-lifesciences.com.
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Zuellig Pharma Acquires Cialis® (Tadalafil) from Lilly in Singapore
Hashtag: #ZuelligPharma #EliLillyandCompany #Cialis #Healthcare #MensHealth #Healthcare #Pharmaceuticals
https://www.zuelligpharma.com/
https://www.linkedin.com/company/zuellig-pharma
The issuer is solely responsible for the content of this announcement.
About Zuellig Pharma
Zuellig Pharma is a leading healthcare solutions company in Asia, and our purpose is to make healthcare more accessible to the communities we serve. We provide world-class distribution, commercialization, and clinical trial support services, underpinned by a strong culture of innovation to support the growing healthcare needs in this region. The company was founded a hundred years ago and has grown to become a multibillion-dollar business covering 18 markets with over 12,000 employees. Our people serve more than 200,000 medical facilities and work with over 450 clients, including the top 20 pharmaceutical companies in the world.
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Licensed Watch Dealer Times Avenue Marks Five Years amid Singapore’s Pre-Owned Watch Market Growth
As the global watch industry slows and fraud risks in the secondary channel draw public attention, Times Avenue is among Singapore’s secondhand luxury watch specialists seeing sustained growth on the back of shifting buyer preferences and tightening consumer scrutiny
SINGAPORE – Media OutReach Newswire – 3 August 2026 – Times Avenue by Horology Maison marks its five-year anniversary in 2026, as Singapore’s pre-owned luxury watch market expands amid a broader slowdown in the global watch industry.
A Growing Secondary Market and the Case for Regulated Dealers
The Bloomberg Subdial Watch Index, which tracks the 50 most-traded references by transaction value, recorded its best half-year performance since early 2022 in the first half of 2025, reflecting a broader shift in buyer preference towards the secondary channel.
The growth of the pre-owned segment has been driven by a combination of factors, including tighter supply of popular references at authorised dealers, record gold prices lifting new watch retail costs, and a shift among buyers towards immediate availability and market-reflective pricing.
Founded in 2020, Times Avenue has grown alongside this trend, transacting more than 3,000 authenticated timepieces from its Beach Road boutique over its first five years of operation. The boutique’s inventory is weighted towards luxury Swiss timepieces including Rolex, Patek Philippe, Audemars Piguet, Tudor and Cartier, with a focus on sought-after references that are typically subject to long waiting lists in the primary market.
At the same time, authentication and fraud risks in the secondary channel have drawn public attention, including the recent prosecution of an Italian national who attempted to trade a “fake” Rolex GMT Saru at a Singapore retailer. Both developments underline the importance of sourcing from licensed, regulated dealers.
Licensed secondhand goods dealers like Times Avenue operate under frameworks that impose customer due diligence, transaction reporting, record-keeping, and stock movement obligations. Exempted by the Singapore Police Force and a fully regulated dealer under the Ministry of Law, Times Avenue ensures that every watch sold undergoes rigorous in-house authentication before it reaches the client, and each piece is covered by an in-house warranty, giving buyers assurance of authenticity for every transaction.
Times Avenue also offers in-person buying from the public, trade-ins, consignment, and authentication, alongside retail, covering both the acquisition and resale ends of the secondary market.
Clients and prospective buyers can view current inventory, arrange private viewings, or request a sourcing consultation at https://horologymaison.com/contact-us/.
Hashtag: #TimesAvenue #PreOwnedWatches #LuxuryWatchesSingapore #WatchCollector #HorologyMaison
https://horologymaison.com/
https://www.facebook.com/timesavenuesg
https://www.instagram.com/timesavenuesg/
carousell:
https://www.carousell.sg/u/timesavenuesg/
telegram:
https://t.me/timesavenue
The issuer is solely responsible for the content of this announcement.
Times Avenue by Horology Maison
Times Avenue by Horology Maison is a Singapore-based luxury watch grey dealer established in 2021, offering authenticated new and pre-owned timepieces from
Rolex, Patek Philippe, Audemars Piguet, Tudor, Cartier and other leading maisons. The company provides retail, buying, trade-in, consignment, sourcing and authentication services from its boutique at 371 Beach Road #02-55 City Gate, Singapore 199597. Times Avenue by Horology Maison is registered with the Ministry of Law as a Regulated Dealer (Registration No. PS20220002864) and holds SPF Exempted Second-Hand Goods Dealer status.
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De Beers Group debuts Desert diamonds in Shanghai
Over 200 industry leaders, trendsetters and cultural figures gather at The Orbit to celebrate the much-anticipated launch event
SHANGHAI, CHINA – Media OutReach Newswire – 3 August 2026 – De Beers Group unveiled the Desert diamonds campaign for Asia at West Bund Orbit in Shanghai. The immersive experience brought to life the authenticity, individuality and inner radiance embodied by Desert diamonds. Generating significant buzz across Shanghai, the event attracted distinguished guests, including government officials and ambassadors, retailers and industry partners, media and cultural influencers, artists and designers.
Designed by British architect Thomas Heatherwick, the West Bund Orbit’s fluid, ribbon‑like form resonates with Desert diamonds’ narrative of individuality, naturalness and fluidity, offering a visually perfect setting for the launch. The highlight of the evening was a sacred gong‑striking ceremony, symbolising the opening of a new era for Desert diamonds. Officiating at the gong-striking ceremony were Lynn Serfaty, General Manager, Natural Diamonds, De Beers Group; Annie Wong, Chief Operating Officer of Chow Tai Fook Jewellery Group; Winston Chow, Deputy General Manager of Chow Sang Sang Jewellery Group and Tommy Tse, Deputy CEO at Tse Sui Luen Jewellery Group. The ring the bell ceremony is accompanied by Loletta Lai, VP, Natural Diamond Marketing, APAC, De Beers Group and Sean Lin, VP, Sales, De Beers Group.
Government and diplomatic leaders joined the celebration to offer their congratulations. Taking the stage for a group photo were Mr. Sohail Shaikh, UK Deputy Trade Commissioner to China, UK Government / FCDO; Mr. Tom Simpson, MD, China, China-Britain Business Council; Ms. Phuti Joyce Tsipa, South African Consul-General in Shanghai; Ms. Bertha Amakali, Minister Counsellor of Namibia to China; Mr. Lin Qiang, President of Shanghai Diamond Exchange Center; Ms. Xu Yilei, Managing Director of the Natural Diamond Council Greater China; Ms. Meng Xiaojun, Chief Economist of NGTC; Shridaran Pillay, VP Government Affairs, De Beers Group, underscoring the event’s cross‑cultural significance.
“Desert diamonds captures the untamed beauty and power of the desert,” said Lynn Serfaty, “In China, natural diamonds are not imports—their origins are deeply rooted in ancient civilisation. The desert itself resonates with the Chinese cultural appreciation for transcendence, resilience, and the harmony between heaven and humanity.”
“Today’s consumers seek individual expression, true self, and self‑reward,” she continued, “Each Desert diamond is a response to this desire. Every Desert diamond presents a uniquely warm, natural colour and carries the imprint of billions of years. It is this cultural resonance that is driving the growing interest and appreciation of Desert diamonds in the Chinese market, representing the values most precious in our time: authenticity, individuality, and inner radiance.”
Departing from traditional jewellery launch formats, De Beers Group invited four “Real People” who embody the spirit of authenticity through their real‑life journeys to reveal the essence of Desert diamonds. The event opened with Desert diamonds “Real People” and sound healer Lear Tsui’s ethereal “Healing Trace” gong performance, guiding guests into a serene state of inner exploration. In the performance segment “Colour of Origin” that followed – Guo Yu’ang, a young Peking opera artist of the Mei School, honoured tradition with a graceful and elegant aria, conveying the beauty of heritage. The only female “Real People”, Shi Wei, China’s first F1 Academy female driver, made a stunning appearance wearing Desert diamonds jewellery at the “Blade of Resilience” segment. She shared with conviction: “True strength is often not outwardly expressed but built through intense focus. Just like the formation of natural diamonds—seemingly silent, yet enduring pressure over eons to achieve transformation.” Taking the stage at the finale “Ray of Refraction”, stand‑up comedian Liu Yang ignited the room with a series of humorous and heartfelt performances, and amidst the laughter, he led everyone into the moment of the very first reveal of Desert diamonds jewellery. Liu Yang shared: “True brilliance is not about being flawless, but about embracing every aspect of yourself, just as Desert diamonds reflects a unique individuality through the natural beauty of diamonds.”
At the heart of the celebration was a curated jewellery art exhibition, presenting Desert diamonds jewellery masterpieces by Chow Tai Fook, Chow Sang Sang and Tse Sui Luen, alongside De Beers Group’s iconic three‑stone collection and loose Desert diamonds. De Beers Group creatively partnered with bamboo weaving artist Xu Mingyu, who used the intangible cultural heritage of bamboo weaving to create immersive art installations throughout the venue. The Desert diamonds jewellery was placed amidst an intricate interplay of bamboo rhythms, sparking a poetic dialogue between contemporary jewellery design and millennia‑old craftsmanship. This distinctive Eastern aesthetic not only offered a fresh visual delight, but also interpreted the beauty of individuality, the authenticity of craftsmanship, and the radiance of time‑honoured tradition embodied by Desert diamonds from a local perspective, further underscoring De Beers Group’s Building Forever sustainability commitment.
To bring the experience to a memorable close, guests continued the journey through sensory party, where sound, scent and imagery combined to evoke the beauty at the heart of Desert diamonds. Interactive zones included a sand art experience allowing guests to co‑create with their fingertips, feeling the flow and eternity of the desert, a Gong Sound healing session using resonant frequencies to guide guests into a state of calm and introspection, and a Scents of the Desert fragrance experience blending warm amber and deep woody notes to outline the raw, pure beauty of the desert earth. Each experience acted as a different facet of a Desert diamond, collectively reflecting the themes of authenticity, individuality, and inner radiance.
To delve deeper into the spirit of the theme, De Beers Group hosted a series of panel talks, offering different perspectives on the evolving role of natural diamonds in modern life. Consumers were invited to participate in Natural Diamond Masterclasses, where they learned about the rarity, uniqueness and enduring value of natural diamonds, and gained further understanding of how to distinguish natural diamonds from laboratory‑grown diamonds. In addition, enamel painting workshops allowed guests to explore the dialogue between traditional craftsmanship and contemporary design.
Desert diamonds opens a new chapter in the celebration of natural diamonds, honouring their deep‑earth origin, inherent rarity, and cross‑cultural significance as symbols of individuality, natural beauty and self‑reward. Today, consumers increasingly look for pieces that reflect not only who they are, but how they choose to live, celebrate and express themselves. Desert diamonds answers that desire with a natural diamond expression shaped by individuality, authenticity and inner radiance. Looking ahead, De Beers Group will continue to celebrate the enduring wonder of natural diamonds and inspire a new generation to discover their relevance in today’s world. Desert diamonds breathe new life into “A Diamond is Forever”—because natural diamonds belong not only to eternity, but also to the here and now.
Please follow the official accounts to find more information regarding Desert diamonds.
| De Beers Group Official Website www.debeersgroup.com |
Natural Diamond Instagram Page: @ADiamondisForeverhk |
Hashtag: #Naturaldiamonds #Diamonds #DeBeersGroup #Desertdiamonds #ADiamondisForever
The issuer is solely responsible for the content of this announcement.
About De Beers Group
Established in 1888, De Beers Group is the world’s leading diamond company with expertise in the exploration, mining, marketing and retailing of diamonds. Together with its joint venture partners, De Beers Group employs more than 20,000 people across the diamond pipeline and is the world’s largest diamond producer by value, with diamond mining operations in Botswana, Canada, Namibia and South Africa. Innovation sits at the heart of De Beers Group’s strategy as it develops a portfolio of offers that span the diamond value chain, including its jewellery houses, De Beers London and Forevermark, and other pioneering solutions such as diamond sourcing and traceability initiatives Tracr and GemFair. De Beers Group also provides leading services and technology to the diamond industry in the form of education and laboratory services and a wide range of diamond sorting, detection and classification technology services. De Beers Group is committed to ‘
Building Forever,’ a holistic and integrated approach to sustainability that underpins our efforts to create meaningful impact for the people and places where our diamonds are discovered. Building Forever focuses on three key areas where, through collaborations and partnerships around the globe, we have an enhanced ability to drive positive impact; Livelihoods, Climate and Nature. De Beers Group is a member of the Anglo American plc group. For further information, visit
www.debeersgroup.com.


