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CK Life Sciences Files Patent Applications for Circular mRNA TROP2 Cancer Vaccine

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Breast Cancer Animal Studies Show Unprecedented Anti-Cancer Efficacy of 100% Tumor Growth Inhibition

HONG KONG SAR – Media OutReach Newswire – 11 April 2025 – CK Life Sciences Int’l., (Holdings) Inc. (“CK Life Sciences”), a leader in cancer vaccine development, announces the latest progress in its pharmaceutical R&D, namely the filing of an Original Grant Patent application in Hong Kong and a provisional patent application in the United States for novel cancer vaccines targeting Trophoblast Cell Surface Antigen 2 (“TROP2”).

TROP2 is a cell surface glycoprotein that is overexpressed in a wide range of cancers, including breast, lung, pancreatic, and colorectal cancers. This protein plays a critical role in cell proliferation, migration, and invasion, and its overexpression is frequently linked to aggressive tumor behavior and poor clinical outcomes. Given its high expression in cancer cells and minimal presence in normal tissues, TROP2 has emerged as a promising therapeutic target in oncology.

TROP2-positive triple-negative breast cancer animal study demonstrated 100% tumor growth inhibition

TROP2 cancer vaccines covered by the patent application include innovative circular mRNA (circRNA) and fusion protein vaccine constructs that can induce robust T cell immune responses and have demonstrated impressive tumor growth inhibition in preclinical studies of triple-negative breast cancer and colorectal cancer. The results of animal studies involving triple-negative breast cancer (“TNBC”) have been encouraging, with mouse models showing 100% tumor growth inhibition after receiving the TROP2 cancer vaccine. Overall, 100% inhibition of tumor growth was achieved in four of the five studies when mice were treated with a TROP2 vaccine candidate, while the remaining study demonstrated approximately 80% tumor growth inhibition.

Triple-negative breast cancer disproportionately prevalent and aggressive among Asian women

The results of animal studies of the TROP2 cancer vaccines are of particular relevance to the Asian region. Breast cancer rates in Asia are rising sharply, with younger women widely affected. In particular, TNBC shows both higher prevalence and more aggressive behavior in Asian populations compared to Western counterparts. Additionally, TNBC has fewer treatment options and demonstrates significantly higher rates of metastasis and recurrence than other breast cancer subtypes.

Unprecedented anti-cancer efficacy

“TROP2 is an exciting therapeutic target and preclinical studies of our cancer vaccine in triple-negative breast cancer exhibited 100% inhibition of tumor growth, demonstrating unprecedented anti-cancer efficacy. We look forward to advancing our TROP2 cancer vaccine expeditiously into clinical trials to benefit patients and believe it holds significant potential in preventing cancer recurrence,” said Dr. Melvin Toh, Chief Scientific Officer at CK Life Sciences.

Data on the TROP2 cancer vaccines will be presented at upcoming cancer conferences. In recent years, CK Life Sciences has showcased its growing early-stage cancer vaccine pipeline through preclinical data presentations at leading oncology conferences, alongside the filing of multiple patents. Developed in its Hong Kong-based R&D laboratories, these innovative vaccines target a broad spectrum of tumor antigens, immune checkpoint proteins, and other key components within the tumor-immune microenvironment.

Hashtag: #CKLifeSciences #CancerVaccines #R&D #BreastCancer #PatentApplication #Pharmaceutical

The issuer is solely responsible for the content of this announcement.

About CK Life Sciences

CK Life Sciences Int’l., (Holdings) Inc. (stock code: 0775) is listed on the Stock Exchange of Hong Kong. With a mission of improving the quality of life, CK Life Sciences is engaged in healthcare research and development, with operating businesses that enable its R&D sustainability. Regarding pharmaceutical research and development, CK Life Sciences’ operations are focused on conducting research and development into cancer vaccines and pain management solutions. CK Life Sciences is a member of the CK Hutchison Group. For additional information, please visit .

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iQOO 15R Named Official Gaming Phone for 2026 Asian Games Esports Qualifiers: Honor of Kings

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The performance-focused smartphone will support tournament-level mobile gameplay with stable performance, responsive controls and sustained power.

DONGGUAN, CHINA – Media OutReach Newswire – 19 June 2026 – iQOO, a smartphone brand built for high-performance mobile gaming experiences, today announced that the iQOO 15R has been named the Official Gaming Phone for the 2026 Asian Games Esports Qualifiers: Honor of Kings.

iQOO

As an official esports title of the Asian Games, Honor of Kings brings together competitive mobile esports players from across the region. Through this partnership, iQOO will support the Qualifiers with a device designed for competitive mobile gaming, reinforcing the brand’s commitment to supporting powerful, stable and immersive experiences for players and fans.

Supporting Tournament-Level Mobile Esports

Competitive mobile esports requires more than peak performance. Players often rely on consistent frame rates, responsive touch control and reliable power throughout extended matches. With the iQOO 15R serving as the Official Gaming Phone for the Qualifiers, iQOO aims to bring its performance-driven technology into a professional tournament setting and support players with a device built for speed, control and sustained gameplay.

Built for Stable, High-Intensity Gameplay

Designed as a performance-focused smartphone, the iQOO 15R is equipped to support the high demands of mobile gaming. Powered by the Snapdragon® 8 Gen 5 Mobile Platform and Monster HyperCore Engine, the device is engineered to help deliver stable frame rates and responsive gameplay during extended sessions.

The Supercomputing Chip Q2 is designed to enhance visual clarity for a more immersive gaming experience, while the Super Touch Control Chip is designed to improve input accuracy and control response. In addition, the advanced cooling system and large-capacity Silicon Anode Battery with fast charging help provide the sustained performance and power required for tournament-level play.
Hashtag: #iQOO

The issuer is solely responsible for the content of this announcement.

About iQOO

iQOO, a sub-brand of vivo, differentiates itself in performance and Esports experience. iQOO leverages the research, quality assurance and after-sales service expertise of vivo, and follows the brand ethos of i Quest On and On to push boundaries, innovate boldly and share the excitement of exploring future technology. With products offering Esports-standard capabilities, iQOO aims to become the top choice of consumers who are passionate about performance and gaming.

For more information, please visit .

About Honor of Kings

Developed by TiMi Studio Group, Honor of Kings has become the world’s most-played MOBA. In 2025, the combined MAU of Honor of Kings titles surpassed 260 million. Featuring highly detailed and diverse character and battlefield design plus music created by world renowned composers including Hans Zimmer, Joe Hisaishi, and Howard Shore, Honor of Kings immerses players in a unique and colorful universe. Honor of Kings prides itself on being free to play and fair to win, with success determined by players’ skills and tactics. Honor of Kings is also home to a thriving esports ecosystem supporting competitive play from grassroots amateurs to elite professionals. To learn more about Honor of Kings, follow on , , , , or visit the official of Honor of Kings.

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ZEEKR Surpasses 800,000 Global Deliveries and Unveils Global Expansion Strategy for Dual Flagship 9-Series Models

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HONG KONG SAR – Media OutReach Newswire – 19 June 2026 – The 2026 International Automotive and Supply Chain Expo (Hong Kong) officially opened today. Under the theme “Luxury, Elevated to a New Realm”, ZEEKR unveiled the global expansion strategy for its dual flagship 9-Series models — the ZEEKR 9X and ZEEKR 009 Grand.

As a key gateway connecting China with global markets, Hong Kong serves as an important benchmark for the premium automotive industry and a strategic platform for luxury brands expanding internationally. Launching the global strategy for the 9-Series in Hong Kong marks a significant new chapter in ZEEKR’s growth across the global premium new energy vehicle market.

800,000 Deliveries Milestone Underscores ZEEKR’s Global Growth Momentum

Strong market performance continues to support ZEEKR’s expansion in the global premium new energy vehicle segment. As of June 16, 2026, ZEEKR’s cumulative global deliveries officially exceeded 800,000 vehicles, marking a major milestone for the brand.

In Hong Kong, ZEEKR has maintained strong momentum. From January to May 2026, ZEEKR captured a 40.7% market share of Hong Kong’s luxury vehicle segment, ranking first among all luxury automotive brands. The ZEEKR 009 ranked as Hong Kong’s best-selling luxury MPV, while the ZEEKR 7X became the city’s best-selling luxury SUV.

Across key international markets, ZEEKR continues to achieve strong results. In Thailand, the brand was the best-selling luxury pure-electric MPV brand in 2025 and retained its leadership position from January to May 2026. In Malaysia, ZEEKR ranked No.1 among luxury pure-electric brands during the same period, with the ZEEKR 7X leading the luxury electric SUV category and the ZEEKR 009 remaining the top-selling luxury electric MPV. In Australia, ZEEKR continued to lead the luxury SUV segment priced above AUD 65,000 from January to May. In Mexico, the ZEEKR 7X secured the monthly luxury EV sales title in both April and May.

Dual Flagship 9-Series Models Showcase ZEEKR’s Technology-Luxury Vision

At this year’s expo, ZEEKR is showcasing five models spanning family mobility, executive transportation and flagship luxury, highlighting the breadth of its premium product portfolio.

The ZEEKR 9X, ZEEKR’s new global flagship of ultra-luxury SUV, is built on the SEA-S architecture and features a 900V high-performance silicon carbide electric drive system delivering more than 1,030 kW of maximum power. Four integrated safety structures combined with extensive use of 2,000 MPa ultra-high-strength steel contribute to a torsional rigidity rating of 41,600 N·m/deg, setting a new benchmark for safety in the hybrid SUV segment. The ZEEKR 9X recently opened pre-sales in the Middle East, where it has received strong market interest. The model is scheduled to expand into key markets across Latin America, Central Asia and Europe.

The ZEEKR 009 Grand, the brand’s global ultra-luxury four-seater flagship MPV, features a 720-degree comprehensive safety architecture and the world’s first integrated die-cast C-ring cabin structure, delivering segment-leading rear-seat protection. The second row is equipped with two ultra-soft aniline leather executive seats featuring 20 massage points and an industry-leading seven-zone graphene heating system, creating an exceptional luxury experience for rear passengers. The right-hand-drive version of the ZEEKR 009 Grand is scheduled to launch in Hong Kong in the fourth quarter of 2026.

The ZEEKR 8X, a super hybrid high-performance flagship SUV, also makes its Hong Kong debut. Built on the SEA-S Super Hybrid Architecture, the ZEEKR 8X delivers a flagship experience across four key dimensions: performance, intelligence, safety and comfort.

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Expanding Global Capabilities and Opening a New Chapter of Technology Luxury

As its product lineup continues to grow and its international footprint expands, ZEEKR is accelerating the development of a comprehensive global operating system spanning R&D, product planning, market operations and customer services. Today, ZEEKR’s overseas business covers more than 60 major cities worldwide with a rapidly growing global user base.

As the global automotive industry accelerates toward electrification and intelligent mobility, the luxury vehicle market is entering a new era in which technological innovation is redefining the premium experience. Leveraging Hong Kong’s position as a globally connected international hub, ZEEKR will continue to deepen its global presence and advance the evolution of luxury through innovation. Through cutting-edge technologies, exceptional products and comprehensive lifecycle services, ZEEKR is committed to delivering a distinctive technology-luxury mobility experience for customers around the world.

Hashtag: #ZEEKR

The issuer is solely responsible for the content of this announcement.

About Zeekr

Zeekr is the global luxury electric vehicle technology brand from Geely Auto Group. Utilizing advanced software-defined architectures and cutting-edge propulsion technologies, Zeekr is dedicated to creating a fully integrated user ecosystem with innovation at its core.

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A Decade of Sharing the Flavors of China: ‘Chinese Restaurant’ Stays True to Its Mission Through Food and Culture

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CHANGSHA, CHINA – Media OutReach Newswire – 19 June 2026 – Carrying the warmth of everyday life and the richness of Chinese civilization, Chinese Restaurant embarks on a new chapter as it celebrates its 10th anniversary. Marking this milestone, Chinese Restaurant: Nanyang Memories Season makes its highly anticipated return, with partners Huang Xiaoming, Wang Junkai, Hannah Quinlivan (Kun Ling), Jiang Yan, Jin Mengjia, Zhang Yaqi, Lin Shuwei, and the rest of the team ready to begin a heartwarming journey through Southeast Asia. The new season will premiere on June 19, airing every Friday at 12:00 p.m. (Beijing Time) on Mango TV and at 10:00 p.m. on Hunan TV.

Over the past nine years, Chinese Restaurant has traveled across multiple countries and regions, including Thailand, France, Italy, and Hungary. Looking back on its journey of cultural exchange, the program launched a dedicated Chinese food truck in France, allowing local residents and visitors to conveniently experience authentic Chinese flavors. In Hungary, food served as a unique language that fostered deeper intercultural understanding. During the 50th anniversary of diplomatic relations between China and Italy, the program actively responded to the Belt and Road Initiative, using cultural interaction and culinary exchange to strengthen friendship between the two nations.

Now, standing at the threshold of its second decade, Chinese Restaurant: Nanyang Memories Season returns to Thailand, drawing upon the longstanding cultural, tourism, and people-to-people ties between China and Thailand. Through food and storytelling, the program once again brings Chinese culture to life on Southeast Asian soil.

The new season introduces an innovative business model inspired by traditional Chinese agricultural wisdom, creating a distinctive experience that combines pastoral ecology with the aesthetics of contemporary Chinese dining. New service concepts, including the “Chef’s Table” and “Chef at Home,” offer guests diverse culinary experiences while naturally integrating Chinese cuisine into everyday local life.

For ten years, Chinese Restaurant has remained committed to its original vision: telling authentic and heartfelt Chinese stories while showcasing the unique appeal of Chinese cuisine to global audiences. Through food, the program has helped narrow cultural distances, deepen international understanding, and highlight the confidence, vitality, and inclusiveness of Chinese culture.

The premiere episode of Chinese Restaurant: Nanyang Memories Season coincides with the Dragon Boat Festival, as the seven partners begin a brand-new entrepreneurial adventure in Chiang Mai, Thailand. From unexpected operational challenges and cultural differences to the dynamic interactions among team members with diverse personalities, the journey promises a wealth of memorable moments and compelling stories for viewers.

Over the years, the Chinese Restaurant franchise has consistently used authentic Chinese cuisine as a bridge connecting people across cultures. Every dish reflects the traditions and warmth of Chinese daily life, while every shared meal conveys the spirit and values of Eastern culture. Set against real-world international backdrops, the program vividly presents the depth and richness of Chinese civilization.

Today, Chinese Restaurant is far more than a culinary reality show. It has become a platform for cultural dialogue, mutual understanding, and friendship between China and the world. Through the universal language of food, the program continues to bring people closer together, allowing Chinese flavors and Chinese stories to resonate across borders and leave a lasting impression on audiences worldwide.

Hashtag: #MGTV

The issuer is solely responsible for the content of this announcement.

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