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CK Life Sciences’ Investigational Cancer Vaccines Deliver Promising Results – New Preclinical Study Data to be Presented at the 2025 American Association for Cancer Research (AACR) Annual Meeting

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HONG KONG SAR – Media OutReach Newswire – 22 April 2025 – CK Life Sciences Int’l., (Holdings) Inc. (“the Company”) announced that the Company will be presenting new data from its cancer vaccine research pipeline at the 2025 American Association for Cancer Research (AACR) Annual Meeting in Chicago, USA.

The AACR Annual Meeting is a gathering central to the global cancer research community, bringing together scientists, clinicians, other healthcare professionals, survivors, patients and advocates every year to share the latest breakthroughs and developments in cancer science and medicine. Last year, the 2024 Annual Meeting attracted 23,000 in-person attendees and 6,700 online participants from 78 countries.

In recent years, CK Life Sciences has regularly participated at the AACR Annual Meeting. The 2025 Annual Meeting will be held from 25-30 April. At the event, CK Life Sciences will exhibit posters highlighting data from preclinical studies of investigational cancer vaccines programs targeting (i) PRAME (Preferentially Expressed Antigen in Melanoma), (ii) PD-L1 (programmed cell death ligand 1), (iii) B7-H3 (B7 homolog 3) and (iv) Claudin 6 proteins, respectively.

PRAME is a protein highly expressed in several cancers, including melanoma, liver cancer and leukemia.

PD-L1 is one of the most important immune checkpoint proteins that is highly expressed in cancer cells to block T cell activation in the tumour microenvironment.

B7-H3 is another immune checkpoint protein that modulates T cell responses and is often overexpressed in cancer.

Claudin 6 is a tight junction protein that regulates epithelial barrier integrity and is overexpressed in cancers like breast cancer, lung cancer and endometrial cancer, where it is associated with tumour progression and metastasis.

In addition, CK Life Sciences will be co-presenting with our research collaborator two posters showcasing our Artificial Intelligence (AI)-empowered platform for designing cancer vaccines.

“CK Life Sciences is pleased with the preclinical efficacy results of its investigational cancer vaccines targeting PRAME, PD-L1, B7-H3 and Claudin 6 proteins, and we hope to further advance the research & development of these and other cancer vaccines. We are also excited about the progress achieved in our efforts to develop an AI platform aimed at designing cancer vaccines that are more likely to be immunogenic and clinically effective,” said Melvin Toh, Vice President and Chief Scientific Officer at CK Life Sciences.

Dr. Toh continued, “CK Life Sciences is determined to accelerate its R&D to benefit cancer patients. Currently, a number of therapeutic cancer vaccines are in clinical and discovery/preclinical research stages. Amongst them, seviprotimut-L, a cancer vaccine already in the final research stage, is being tested for the adjuvant treatment of stage IIB or IIC melanoma following definitive surgical resection.

DETAILS ON POSTER PRESENTATIONS:

  • Abstract 853: PDL1-PRAME dual antigen cancer vaccine inhibits melanoma growth in syngeneic mouse model and induces antigen-specific immune responses

Authors: Kin-Tak Chan, Hsin-Wei Chen, Pi-Hui Liang, You-Yu Lin, Tristan Zhang, Melvin Toh

Session Category: Clinical Research
Session Title: Vaccines and Cell Therapies
Session Date and Time: 4/27/2025 2:00 PM – 5:00 PM
Location: Poster Section 35
Poster Board Number: 9

  • Abstract 3533: Claudin 6 vaccines effectively inhibit tumor growth in a syngeneic mouse colon cancer model

Authors: Na Wang, Melvin Toh, Hong Wang

Session Category: Immunology
Session Title: Vaccines, In Situ Vaccines, and Vaccine Combinations
Session Date and Time: 4/28/2025 2:00 PM – 5:00 PM
Location: Poster Section 39
Poster Board Number: 9

  • Abstract 3536: Synergistic effects of combined PD-L1 and B7-H3 fusion protein vaccination in a mouse model of pancreatic cancer
Authors: Kenneth Nansheng Lin, Melvin Toh, Hong Wang
Session Category: Immunology
Session Title: Vaccines, In Situ Vaccines, and Vaccine Combinations
Session Date and Time: 4/28/2025 2:00 PM – 5:00 PM
Location: Poster Section 39
Poster Board Number: 12

  • Abstract 3538: The development of neoantigen-derived peptide vaccine driven by AI epitope design and computer assisted epitope enhancement

Authors: Chi Han Samson Li, Hong Wang, Kin Tak Chan, Genwei Zhang, Jiewen Du, Lipeng Lai, Melvin Toh

Session Category: Immunology
Session Title: Vaccines, In Situ Vaccines, and Vaccine Combinations
Session Date and Time: 4/28/2025 2:00 PM – 5:00 PM
Location: Poster Section 39
Poster Board Number: 14

  • Abstract 3649: Artificial intelligence accelerates shared neoantigen peptide cancer vaccine development

Authors: Genwei Zhang, Jiewen Du, Xiangrui Gao, Zhenghui Wang, Qingxia Zhang, Tongren Liu, Dong Chen, Chi Han Samson Li, Kin Tak Chan, Hong Wang, Melvin Toh, Lipeng Lai

Session Category: Bioinformatics/ Computational Biology/ Systems Biology/ Convergent Science
Session Title: Artificial Intelligence and Machine Learning for Therapeutic Election and Discovery
Session Date and Time: 4/28/2025 2:00 PM – 5:00 PM
Location: Poster Section 45
Poster Board Number: 11

The full abstracts are available in the AACR Online Itinerary Planner, which can be accessed at: https://www.abstractsonline.com/pp8/#!/20273


DISCLAIMER
This press release may contain forward-looking statements regarding the Group’s research and development projects which may involve risks and uncertainties. Actual results may differ materially from expectations discussed in such forward-looking statements.
All information in this press release is for general reference only and is not intended as investment advice or medical advice. CK Life Sciences Int’l., (Holdings) Inc. does not warrant or represent, express or implied, as to the accuracy, completeness or updated status of such information. No liability will be accepted for any loss or damage howsoever arising from or in reliance upon such information.
Copyright ©2025 CK Life Sciences Int’l., (Holdings) Inc. All rights reserved.

Hashtag: #CKLifeSciences #CancerVaccines #R&D #Pharmaceutical #AmericanAssociationforCancerResearch #AACR #PRAME #PD-L1 #B7-H3 #Claudin6Proteins #Melanoma #AI

The issuer is solely responsible for the content of this announcement.

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VF 8 Is Connecting a New Global VinFast Community

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VinFast’s electric SUV is earning loyalty from Vietnam to the Middle East by fitting seamlessly into real lives, long drives, and daily routines.

HAI PHONG, VIETNAM – Media OutReach Newswire – 16 January 2026 – VinFast’s VF 8 is traveling well, winning over drivers across markets with everyday performance, thoughtful design, and uncommon peace of mind.

A VF 8 owner belong to a relatively exclusive, self-selecting club that its maker VinFast have built across the globe. It is the kind of club formed less by marketing than by shared curiosity and a willingness to move early. Owners tend to recognize one another not by badges or decals, but by the confidence that comes from having made a deliberate choice.

The VF 8 holds a special place for VinFast. It was the brand’s first fully international offering, the vehicle tasked with introducing a young Vietnamese automaker to demanding markets abroad. As a result, the car was designed to travel well. Styled in collaboration with Pininfarina, the VF 8 favors clean proportions over visual noise. Beneath the surface, its dual-motor all-wheel-drive system and 402 horsepower provide performance that feels reassuring.

In Vietnam, the VF 8 has appealed to high-mileage drivers like Nguyen Phuong Hoang Dung, a Ho Chi Minh City-based construction project manager who covers about 5,000 kilometers a month. “When you drive that much, comfort and stability directly affect your health, your mindset, and how well you work,” he said. Having spent years with gasoline cars, he switched to the VF 8 in August 2025, drawn by its smooth throttle response and calm, seamless acceleration. Now, with more than 20,000 kilometers behind him, he said, “The more I drive it, the more confident I am that choosing the VF 8 was the right decision.”

As the VF 8 expanded into North America and Europe, it increasingly settled into a simpler role: a dependable everyday vehicle. Robert, who has driven his for more than a year and a half, said it has been “a great vehicle,” adding that “you will not find another this size in the price range they offered it.” For Jonathan, the VF 8 fits neatly into daily routines. “For us it’s a city vehicle with short rides every day, and it answers our needs,” he said. “Very comfortable, impressive performance, good in snow, and strong overall.”

In the Middle East, the VF 8’s appeal sharpens as VinFast pairs the car with ownership benefits that are rare in the segment, including complimentary maintenance coverage for five years or 100,000 kilometers. These are not small details in markets where peace of mind often matters as much as design. “The maintenance package made the decision easy,” said an owner in Dubai. “You know exactly where you stand.”

The idea of a VF 8 community is beginning to take shape. Across markets, it connects drivers in Vietnam, Europe, North America, and the Middle East through a shared understanding of what modern electric ownership can be. Thoughtful design. Capable performance. A clear push toward sustainability without asking drivers to compromise their routines.

For those inside the club, the VF 8 is not simply a statement car. No, something even better. A car that makes sense, day after day, in very different parts of the world.

Hashtag: #VF8 #VinFast

The issuer is solely responsible for the content of this announcement.

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ONYX Hospitality Group Partners with Yee Fung Group to Launch “Y Hotel Nanshan Shenzhen”, Expanding its Portfolio in China

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BANGKOK, THAILAND – Media OutReach Newswire – 16 January 2026 ONYX Hospitality Group, a leading Southeast Asian hospitality management company specialising in hotels, resorts, serviced apartments, and luxury residences, is proud to announce its new partnership with Yee Fung Group to operate Y Hotel Nanshan in Shenzhen, People’s Republic of China.

ONYX Hospitality Group oversees renowned brands including Amari, OZO, Shama, and Oriental Residence across key destinations in the Asia–Pacific region. This agreement marks another significant milestone in strengthening ONYX’s presence in the Chinese market. Scheduled to open in Q4 2026, the hotel supports ONYX’s long-term growth strategy as it works toward its target of managing more than 75 properties by 2030.

Mr Yuthachai Charanachitta, Chief Executive Officer of ONYX Hospitality Group, commented: “This collaboration reflects the strong confidence Yee Fung Group has in ONYX, following our successful partnership in managing Y Hotel Hong Kong. It represents a significant step forward in building on that success and further expanding ONYX’s presence in the Greater China market. At the same time, this partnership reinforces ONYX’s position as a distinctive ‘Regional Player’, well-positioned for stable and sustainable growth across the region.”

Y Hotel Nanshan Shenzhen featuring 82 thoughtfully designed guest rooms and suites, located within YEE FUNG PLACE on a strategically significant site surrounded by key national infrastructure. The area is supported by five major national sea and land ports, including Shekou, Chiwan and Mawan, servicing more than 150 shipping routes. It is also situated at the heart of one of China’s leading innovation and industrial hubs, home to sectors such as integrated circuits, artificial intelligence, biomedicine and the marine economy, alongside more than 50 specialised industrial parks.

Y Hotel Nanshan Shenzhen is ideally suited for leisure travellers, offering convenient accessibility just 35 minutes from Shenzhen Baoan International Airport and 31 minutes from Shenzhen North Railway Station, and only 650 metres from Lilin Subway Station. The surrounding area features vibrant food markets and nightlife destinations such as Nanyi Fang, Shekou Sea World, Green World and Houhai, as well as cultural and recreational attractions including Shenzhen Poly Theatre, Shenzhen Talent Park, Nanshan Museum, Nanshan Park and Shenzhen Bay Park. Guests will also find leading shopping centres nearby, including Walmart, Xinhe Shopping Plaza, Garden City, Haiya Mega Mall, Coastal City and Shenzhen Bay MixC.

Furthermore, the hotel is located close to the headquarters of major national technology companies such as ZTE, Tencent, Huawei, Alibaba, Han’s Laser and Mindray, as well as Shenzhen University, positioning it as both a relaxing retreat and a strategic hub for business travellers seeking comfort alongside a distinctive lifestyle experience.Hashtag: #ONYXHospitalityGroup #YeeFungGroup #YHotel #HospitalityManagement #HotelManagement #LifestyleHotel



The issuer is solely responsible for the content of this announcement.

About ONYX Hospitality Group:

ONYX Hospitality Group, a reputable force in Southeast Asia’s hospitality industry, operates a collection of comprehensive yet complementary brands – Amari, OZO, Shama and Oriental Residence – catering to the distinctive needs of discerning business and leisure travellers in Southeast Asia where their expertise lies. In addition to its brand portfolio, ONYX Hospitality Group also operates additional hospitality services across spa and food and beverage. With over five decades of management experience, the company extends its innovative solutions throughout the region, upholding internationally recognised standards and ensuring optimal operational manoeuvrability. By fostering enduring relationships with like-minded business partners, ONYX Hospitality Group delivers unparalleled experiences in a dynamic and competitive market, meeting the ever-evolving demands of travellers.

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AFERIY Unveils Next-Generation Portable Power Station Nomad1800 at CES

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LAS VEGAS, US – Media OutReach Newswire – 16 January 2026 – As the Consumer Electronics Show (CES) 2026 officially opened, AFERIY, an innovative global brand in the portable clean energy sector, announced the launch of its next-generation portable power station, the Nomad1800, drawing widespread attention from industry professionals and the media.

More Compact Size, Greater Power Output

The AFERIY Nomad1800 keeps the same battery capacity while boosting power output by 50% through system and structural optimization. Weighing 11.6 kg, it is about 10% lighter than the previous model.

Despite its lighter design, it delivers 1800 W rated AC output (peak 3600 W), powering appliances like rice cookers, kettles, car refrigerators, and induction cooktops for camping, RVs, and home emergencies.

Fast Charging: 0–80% in 36 Minutes

The Nomad1800 adopts a hybrid fast-charging solution supporting both AC grid power and solar input. It can charge from 0% to 80% in just 36 minutes, significantly reducing charging time. This fast-charging capability allows the Nomad1800 to adapt to short stops, travel intervals, and unexpected power outages, providing users with efficient and predictable energy support.

Safe and Durable LiFePO₄ Battery

The Nomad1800 is equipped with a 1024 Wh lithium iron phosphate (LiFePO₄) battery supplied by EVE Energy. After more than 4,000 charge and discharge cycles, the battery retains up to 80% of its capacity.

An intelligent BMS monitors voltage, current, and temperature to ensure safe, stable operation even under high load or fast charging.

Industry-Leading Seven-Year Warranty

AFERIY offers the Nomad1800 an industry-leading seven-year warranty on core components and systems, reflecting confidence in its quality, safety, and durability.

Comprehensive Power and Safety Protection

The Nomad1800 features multiple output ports, enabling simultaneous power supply to multiple devices. It also supports UPS functionality, switching within 10 milliseconds during grid power interruptions to protect sensitive equipment such as computers and routers.

Under low-load operation, noise levels remain below 30 dB. In addition, the unit includes built-in LED lighting and an SOS flashing mode to enhance safety during nighttime and emergency use.

For more information, please visit the official AFERIY website or AFERIY on Amazon.

Hashtag: #AFERIY

The issuer is solely responsible for the content of this announcement.

About AFERIY

AFERIY is a global brand focused on portable energy storage and clean energy solutions, committed to providing efficient, safe, and reliable power for outdoor activities, home emergency use, and professional applications.

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