In 2025, the collaboration between the research team of that leading university in Hong Kong and Prof. Nick Wang, Founder and Head of R&D at eefit has led to a critical breakthrough. They discovered that eefit far infrared technology can simultaneously suppress β-amyloid (Aβ) deposition and tau protein hyperphosphorylation, creating an innovative solution for preventing Alzheimer’s disease. The results were published in NeuroMolecular Medicine (Volume 27, Article 34, 2025).

First Study with Evidence of Simultaneous Dual-Pathology Improvement Mechanism in Transgenic Mouse Model

To address the future need for Alzheimer’s disease prevention and treatment in Hong Kong, the research team explored non-pharmacological physical therapies. Using a TgCRND8 transgenic mouse model, they conducted a 28-day irradiation experiment with eefit far infrared light (FIR, wavelength range of 4-20μm) to evaluate its effectiveness in improving disease pathology. The study found:

• Improved cognitive function: The FIR-treated mice group showed significant improvement in cognitive function and memory during the Morris Water Maze Test (MWMT).
• Aβ deposition suppression: Decreased Aβ42/Aβ40 ratio in the cortex, reduced plaque deposits, and increased Aβ clearance.
• Tau protein hyperphosphorylation inhibition: Significantly reduced tau protein phosphorylation levels at different sites, such as Thr205, Ser36, etc., and reduced the formation of neurofibrillary tangles.
• Dual-pathway mechanism: Suppression of neuroinflammatory pathways (reduced IL-1β, TNF-α and increased IL-4) and activation of antioxidant pathways (enhanced Nrf2/HO-1 pathway), achieving dual-pathway protection.

Using a transgenic mouse model, this study confirms for the first time that eefit far infrared technology can simultaneously reduce Aβ deposition and tau protein hyperphosphorylation through physical intervention. Previous studies have only focused on single-pathology interventions, making the significance of this study on the dual-pathway improvement effect groundbreaking.

The Dean of the Faculty of Chinese Medicine at a renowned Hong Kong university said, “As a non-invasive treatment option, far infrared therapy has the potential to delay the disease progression of patients with mild cognitive impairment for several years, thereby reducing the burden on overall medical resources and providing significant assistance to families and caregivers.”

This groundbreaking discovery also provides solid scientific evidence to support the industrial application of eefit far infrared technology.

International R&D Team Drives Industrialisation Capability

To promote the transformation of far infrared technology from scientific research results to industrial applications, eefit has built a global R&D system with scientific research as its core driving force, first collaborating with the “State Key Laboratory of Quality Research in Chinese Medicine” at the Macau University of Science and Technology (M.U.S.T.) to launch the “eefit Biomedical Research Project” in the early years. In 2021, eefit further expanded its global collaboration network by partnering with “Dr. Neher’s Biophysics Laboratory for Innovative Drug Discovery”, founded by Dr. Erwin Neher, Nobel Prize Laureate in Physiology or Medicine, strengthening its R&D capability.

In recent years, multiple international journal articles have confirmed that eefit far infrared technology is effective in the fields of intestinal microecology, rheumatoid arthritis, cerebral stroke, neuroinflammation, and immunomodulation.

Market Response and Social Responsibility Are Equally Important

In tandem with advancing scientific research, eefit is also dedicated to upholding our social responsibilities. In 2024, eefit launched the “eBrain Movement”, which provided brain health services to 212,000 people across our retail stores in Hong Kong. User feedback showed improvement in their bodily conditions, including neurodegenerative symptoms such as headaches, tinnitus, hair loss, hand tremors, nocturia, etc., with unanimous reports of improved sleep quality after treatment. Both this programme and academic research have proven the remarkable effect of eefit far infrared technology in the fields of brain health, sub-health of the middle-aged and elderly, and auxiliary treatment of complex diseases.

Multidimensional Breakthrough in Managing Sub-Health in the Middle-Aged and Elderly​

Based on this technology, eefit has already developed a variety of products, building an all-encompassing “Prevention + Maintenance + Adjustment” health management system, meeting the diverse needs of the middle-aged and elderly population from disease prevention to daily health management:

• Alzheimer’s disease prevention: Reduces Aβ deposits and abnormal tau proteins, reducing the risk of disease.
• Brain health: Relieves neurological problems such as effects of stroke, and enhances brain vitality.
• Chronic pain care: Relieves pains such as neck/shoulder/lower back/leg pain, and rheumatoid arthritis, etc.
• Digestive system regulation: Optimizes gut microbiota and enhances nutrient absorption.

The issuer is solely responsible for the content of this announcement.

About eefit

Based in Hong Kong, eefit has services available throughout the city. With leading service coverage and an innovative product matrix, we provide customers with convenient and efficient health management solutions. This Alzheimer’s disease pathology improvement study further verifies that eefit far infrared technology can put scientific research into practice in daily life. eefit is committed to ongoing investment in technological R&D to propel the advancement and innovation in health technology.

Contact email: De*****@***it.com

Company website: https://bit.ly/45UoKSG

Facebook page: Facebook.com/eefit