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Revolutionary Treatment Introduced in Hong Kong to Combat 2.4-Year Diagnosis Delay and Emotional Struggles in Vitiligo Patients
Vitiligo affects approximately 1% of the population in Hong Kong, translating to an estimated 70,000 patients. Research finds that patients receive a diagnosis after an average of 2.4 year. This prolonged diagnostic process often leads to disappointment and abandonment of treatment, resulting in significant emotional challenges; vitiligo patients are five times more likely to suffer from depression compared to the general population.
Dr Johnny Chan Chun-yin, a Specialist in Dermatology and Venereology, and Dr Rico Li Ching-kwok, a Specialist in Psychiatry, emphasize the availability of various treatment options for vitiligo. This year, a groundbreaking new medication has been introduced in Hong Kong to help patients effectively manage their condition. They encourage patients to seek medical advice early to mitigate the physical and mental burdens associated with vitiligo.
Multi-Faceted Challenges Faced by Vitiligo Patients
Vitiligo is an autoimmune disease in which the immune system erroneously attacks melanocytes, resulting in white patches on the skin. Multiple international studies reveal that vitiligo patients frequently encounter the following challenges:
1. Delayed Treatment Resulting from Diagnostic Challenges
International studies have found that, on average, it takes 2.4 years to receive a diagnosis, which consequently delays treatment.
2. Perception of Untreatability
Research indicates that 57% of vitiligo patients have been informed that their condition is untreatable. As a result, 44.6% of patients choose to abandon their search for effective treatment.
3. Disappointment with Current Treatments
Studies have shown that half of vitiligo patients are dissatisfied with their current treatment options, with 49% reporting that their treatments have been ineffective. Furthermore, 94% of patients express a pressing need for new and improved treatment methods.
4. High Rates of Depression
- Research indicates that over half (58.7%) of vitiligo patients experience mental health issues of different degrees, including anxiety (28.8%) and depression (24.5%).
- The likelihood of depression among vitiligo patients is five times higher than that of the general population.
The Emotional Toll of Misunderstood Conditions: Anxiety and Depression in Patients
Vitiligo not only affects appearance but also leads to significant emotional distress, which is one of the most common comorbidities among patients. Psychiatrist Dr Rico Li notes, “In recent years, I have encountered many patients experiencing emotional distress due to vitiligo. As the onset typically occurs between the ages of 10 and 30, the impact on young patients, especially females, can be profound. They are at an age where they are particularly concerned about their appearance, and often the condition appears suddenly. Diagnostic challenges and the lack of effective treatments in the past can lead to anxiety and depression.”
Dr Rico Li further explains that many patients have historically been informed that vitiligo is untreatable. Family and friends may perceive the condition as harmless, believing there is no cause for concern. “In reality, those around them may not understand the psychological pressure patients endure, which contributes to a higher likelihood of anxiety and depression among vitiligo patients and may even lead to suicidal thoughts.” He emphasizes that stress can trigger or worsen vitiligo symptoms, and if these issues are not addressed, patients may fall into a vicious cycle of worsening skin and emotional problems.
New Treatment Option Receives International Recognition
Dr Johnny Chan stated, “Vitiligo is often confused with tinea versicolor or pityriasis alba. However, doctors can accurately diagnose vitiligo through a thorough assessment of the patient’s medical history, careful evaluation of the skin, skin biopsy, blood tests, and Wood’s lamp examination.” He noted that many patients mistakenly believe that vitiligo is uncontrollable or have tried various treatment methods without significant results, which leads them to abandon treatment prematurely.
While vitiligo cannot be completely cured, there are numerous treatment options available to help improve the condition. Historically, treatments have included ultraviolet light therapy, topical corticosteroids, and oral steroids. Recently, targeted therapies such as non-steroidal topical JAK inhibitors have emerged. Dr Johnny Chan explains, “Topical JAK inhibitor Ruxolitinib cream works by blocking the immune system’s erroneous attack on melanocytes, allowing them to reactivate and gradually restore normal skin color in affected areas.”
Ruxolitinib cream is the first FDA-approved prescription topical treatment for adult and pediatric patients aged 12 and older with non-segmental vitiligo. It was officially introduced in Hong Kong this year. International studies have confirmed that topical JAK inhibitors show promising treatment performance, with approximately 30% of patients experiencing over a 75% improvement in the facial depigmentation index (F-VASI) after 24 weeks of treatment, and more than half achieving at least a 50% improvement. If treatment continues for 52 weeks, about half of the patients may see improvements of over 75%.
Conclusion and Recommendations
Vitiligo can significantly impact both the physical and mental health of patients. In light of this, Dr Johnny Chan and Dr Rico Li offer the following recommendations:
1. Timely Diagnosis
Vitiligo can easily be confused with other dermatological conditions. Patients should consult a doctor as soon as they notice unusual white patches to minimize the risk of treatment delays.
2. Public Education and Awareness
Public understanding of vitiligo is limited, making it difficult for people to appreciate the emotional impact on patients. Strengthening public education is crucial to help the community, as well as the friends and family of patients, better understand and empathize with their experiences. Support from loved ones can alleviate the worsening of skin conditions caused by emotional distress. Friends and family should encourage patients exhibiting symptoms of anxiety or depression to seek help from a psychiatrist.
3. New Treatment Brings Hope to Patients
Many patients have mistakenly believed that vitiligo is untreatable. However, recent medical advances have led to breakthroughs in treatment options, such as the use of topical JAK inhibitor Ruxolitinib cream, which is a new, internationally clinically proven treatment option with favorable therapeutic outcomes.Hashtag: #Vitiligo #AutoimmuneDisease #TopicalJAKInhibitorCream #Ruxolitinib #DrJohnnyChanChuyin #DrRicoLiChingkwok #Anxiety #Depression
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Media OutReach
St. George’s University Prepares Future South Korean Physicians for the Growing Global Cancer Care Challenge
Recognizing the importance of addressing workforce shortage in South Korea, St. George’s University (SGU) School of Medicine in Grenada, West Indies, highlights how its medical education approach supports the development of clinical competencies relevant to cancer care across healthcare settings.
These challenges reflect broader global trends, where cancer care increasingly depends on multidisciplinary teams rather than specialty expansion alone. SGU’s curriculum is designed to build a strong foundation in clinical diagnosis, patient communication and multidisciplinary care, which are essential skills for effective oncology and cancer-related care. Through anatomy labs, simulation-based learning, and integrated digital tools, students develop foundational clinical skills in structured, supervised environments designed to reflect real-world medical practice.
The curriculum also integrates traditional cadaveric dissection with modern 3D anatomical modeling. This blend helps students visualize the human body in a holistic way while reinforcing knowledge through their hands-on interaction. SGU’s simulation lab also enables medical students to have their first direct interaction with ill patients in a safe, simulated learning environment.
On top of core medical training, SGU offers early exposure to prevention, diagnosis and patient-centered care to prepare graduates to tackle complex health issues. SGU has developed long-standing relationships with more than 75 established hospitals and clinical centers in the US and UK. These clinical placements provide exposure to diverse patient populations and care environments, including settings where cancer diagnosis and management are part of routine clinical practice.
South Korean SGU alumni are contributing to healthcare systems through roles that intersect with cancer diagnosis, treatment coordination, and long-term patient care. For example, Dr. Julia Hweyryoung Cho, MD 2022 is practicing internal medicine, which plays a crucial role in cancer care. Internal medicine physicians are often involved in the initial diagnosis of cancer, managing complex medical conditions that may arise during treatment and providing long-term comprehensive care and survivorship planning for patients with a history of cancer.
In observance of World Cancer Day 2026, SGU encourages all medical professionals and organizations to collaboratively address global cancer care challenges. This includes recognizing and meeting the cancer healthcare needs of individuals and communities in South Korea.
For more information on the programs and tracks available through SGU School of Medicine, visit SGU’s website.Hashtag: #St.George’sUniversity
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Finalists and Semifinalists for $1 Million Seeding The Future Global Food System Challenge Announced
Created and funded by Seeding The Future Foundation and, for the first time, hosted by Welthungerhilfe (WHH), the Challenge attracted a record 1,600+ applications from innovator teams in 112 countries, underscoring growing global momentum for food systems transformation.
Following a multi-stage, rigorous international review process, 36 teams have advanced across three award levels. These include 16 Seed Grant Finalists (competing for 8 awards of USD 25,000), 12 Growth Grant Semifinalists (competing for 3 awards of USD 100,000), and 8 Seeding The Future Grand Prize Semifinalists (competing for 2 awards of USD 250,000).
“Hosting the GFSC reflects Welthungerhilfe’s commitment to accelerating bold, scalable innovations where they are needed most. This year’s diversity of solutions underscores the complexity of food system challenges and the creativity of innovators worldwide.” said Jan Kever, Head of Innovation at Welthungerhilfe
The submitted innovations span diverse themes and approaches, including climate-smart production, nutrient-dense foods, food loss reduction, and inclusive market models, reflecting the complexity and interconnected nature of today’s food systems challenges.
“The Seeding The Future Global Food System Challenge exists to catalyze impactful, bold, and scalable innovations that advance food systems transformation. We are excited to work alongside Welthungerhilfe as a trusted partner and host of the Challenge and are encouraged by the quality and diversity of innovations emerging from this first year of collaboration.” said Bernhard van Lengerich, Founder and CEO of Seeding The Future Foundation
While the number of awards is limited, all semifinalists and finalist applicants plus all applicants with any prior recognition of other innovation competitions can join the STF Global Food System Innovation Database and Network—currently in beta testing with the Food and Agriculture Organization of the United Nations—vastly expanding their visibility and reach across a global audience.
List of 2025 GFSC Seed Grant Finalists, Growth Grant and Seeding The Future Grand Prize Semifinalists
Find details here: welthungerhilfe.org/gfsc-finalists
Seeding The Future Grand Prize Semi-Finalists
- CNF Global, Kenya
- ZTN Technology PLC, Ethiopia
- One Acre Fund, Rwanda
- Sanku, Tanzania
- Nabahya Food Institute (NFI), Democratic Republic of the Congo
- ABALOBI, South Africa
- metaBIX Biotech, Uruguay
- Nurture Posterity International, Uganda
Growth Grant Semi-Finalists
- Baobaby, Togo
- Safi International Technologies Inc., Canada
- Centro Internacional de Mejoramiento de Maíz y Trigo (CIMMYT), Mexico
- Farmlab Yeranda Agrisolution Producer Company Limited, India
- Banco de Alimentos Santa Fe (BASFE), Argentina
- Chartered Consilorum (Pty) Ltd, South Africa
- American University of Beirut, Environment and Sustainable Development Unit (ESDU at AUB), Lebanon
- The Source Plus, Kenya
- Iviani Farm Limited, Kenya
- Rwandese Endogenous Development Association, Rwanda
- NatureLEAD, Madagascar
- Ndaloh Heritage Organisation, Kenya
Seed Grant Finalists
- Inua Damsite CBO, Kenya
- World Neighbors, United States
- Keloks Technologies Ltd, Nigeria
- REBUS Albania, Albania
- Tanzania Conservation and Community Empowerment Initiative (TACCEI), Tanzania
- Intrasect, Switzerland
- VKS AGRITECH, India
- Murmushi People’s Development Foundation, Nigeria
- Levo International, Inc., United States
- Effective Altruism Research Services Ltd, Uganda
- Taita Taveta University, Kenya
- CultivaHub, Democratic Republic of the Congo
- Resource Hub for Development (RHD), Kenya
- FUTURALGA S.COOP.AND, Spain
- West Africa Centre for Crop Improvement, University of Ghana, Ghana
- Sustainable Solutions Kenya, Kenya
Hashtag: #TheFutureGlobalFoodSystemChallenge
The issuer is solely responsible for the content of this announcement.
About Seeding The Future Foundation
STF is a private nonprofit dedicated to ensuring equitable access to safe, nutritious, affordable, and trusted food. It supports innovations that transform food systems and benefit both people and planet. More at Seeding the future.
About Welthungerhilfe
WHH is one of Germany’s largest private aid organizations, striving for a world without hunger since 1962. More at: Welthungerhilfe (WHH)
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PolyU develops novel antibody targeting fat cell protein, offering new approach to treating metabolism-related liver cancer
Metabolic dysfunction-associated steatotic liver disease (MASLD), commonly known as fatty liver disease, currently affects around a quarter of the global population and is an important risk factor for liver cancer. In affected individuals, fat cells induce insulin resistance and chronic inflammation, leading to excessive fat accumulation in the liver. This ultimately impairs liver function and may progress to liver cancer. Treatment options for MASLD-induced liver cancer remain limited and the effectiveness of current immunotherapies is suboptimal.
A breakthrough study led by Prof. Terence LEE, Associate Head and Professor of the PolyU Department of Applied Biology and Chemical Technology, and his research team has revealed that an adipocyte-derived protein, known as fatty acid-binding protein 4 (FABP4) is a key driver that accelerates tumour growth. Through mass spectrometry, the team confirmed that patients with MASLD-induced liver cancer had markedly elevated FABP4 levels in their serum. Further investigations showed that FABP4 activates a series of pro-proliferative signalling pathways within cells, causing cancer cells to multiply and grow more rapidly.
Prof. Lee’s team has successfully developed a monoclonal antibody that neutralises FABP4. This antibody not only inhibits the growth and proliferation of FABP4-driven cancer stem cells, but also enhances the ability of immune cells to combat cancer.
Prof. Lee said, “This neutralising antibody against FABP4 demonstrates significant potential in inhibiting tumour growth and activating immune cells, providing a complementary approach to current immunotherapy strategies. Our findings highlight that targeting adipocyte-derived FABP4 holds promise for treating MASLD-induced liver cancer.”
Prof. Lee added that gaining deeper insights into how adipocyte-derived FABP4 affects liver cancer cells helps to explicate the disease mechanisms of liver cancer, particularly in obese individuals. Intervening in the relevant signalling pathways could provide effective methods to combat this aggressive malignancy.
Prof. Lee believes that, as this adipocyte-targeted immunotherapy continues to mature, it will bring more treatment options to MASLD patients. He remarked, “If its efficacy can be proven in clinical trials, it could offer new hope to many affected individuals.”
The research is supported by the Innovation and Technology Fund of the Innovation and Technology Commission of the Government of the Hong Kong Special Administrative Region of the People’s Republic of China. PolyU has filed a non-provisional patent for the developed antibody and is continuing to optimise its binding affinity to facilitate future clinical applications.
Hashtag: #PolyU #FattyLiver #Cancer #LiverCancer #理大 #香港理工大学 #肝癌 #癌症 #脂肪肝
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