Media OutReach
Triple agonist UBT251 delivers up to 19.7% mean weight loss after 24 weeks in phase 2 trial in China
- UBT251 is a triple agonist of the receptors for GLP-1, GIP and glucagon (triple G), being jointly developed by United Biotechnology and Novo Nordisk
- In a placebo-controlled phase 2 trial in Chinese people with overweight or obesity, UBT251 led to a statistically significant mean weight loss of up to 19.7% after 24 weeks
- UBT251 appeared to have a safe and well-tolerated profile consistent with incretin-based therapies.
GUANGDONG, CHINA & BAGSVÆRD, DENMARK – Media OutReach Newswire – 24 February 2026 – The United Laboratories International Holdings Limited (TUL) and Novo Nordisk A/S (Novo Nordisk) today announced topline results from a Chinese phase 2 trial of UBT251, a triple agonist of the receptors for GLP-1, GIP, and glucagon (triple G).
UBT251 is being jointly developed by TUL’s wholly-owned subsidiary The United Bio-Technology (Hengqin) Co., Ltd. (United Biotechnology) and Novo Nordisk under an agreement signed in March 2025. United Biotechnology is responsible for development in Chinese mainland, Hong Kong, Macau and Taiwan, while Novo Nordisk is responsible for development in the rest of the world.
The trial, conducted by United Biotechnology, investigated the safety and efficacy of once-weekly injectable 2 mg, 4 mg and 6 mg doses of UBT251 compared to placebo in Chinese people with overweight or obesity. From a baseline mean body weight of 92.2 kg, the highest mean weight loss observed for people treated with UBT251 was 19.7% (-17.5 kg) compared to 2.0% (-1.6kg) in the placebo group after 24 weeks of treatment[i].
Moreover, all dose groups of UBT251 showed statistically significant improvements relative to placebo on key secondary endpoints, including waist circumference, blood glucose, blood pressure and lipids.
In the trial, UBT251 appeared to have a safe and well-tolerated profile. The most common adverse events were gastrointestinal, and the vast majority were mild to moderate and diminished over time, consistent with incretin-based therapies.
“The success of the phase 2 clinical trial of UBT251 in China represents another significant milestone in TUL’s innovation-driven development,” said Mr Tsoi Hoi Shan, Chairman of TUL. “We will continue to focus on chronic diseases, including endocrine and metabolic disorders, accelerate the further development of UBT251, and strive to bring more high-quality treatment options to patients worldwide at the earliest opportunity.”
“We are very encouraged by these data from the trial in China, which demonstrate the potential of UBT251 and its differentiated clinical profile and safety and tolerability profile,” said Martin Holst Lange, executive vice president, chief scientific officer and head of Research and Development at Novo Nordisk. “We look forward to reporting data from a global trial with UBT251 conducted by Novo Nordisk next year.”
Novo Nordisk recently initiated a global phase 1b/2a trial investigating the safety, tolerability, pharmacokinetics and pharmacodynamics of different doses of UBT251 for up to 28 weeks in around 330 people living with overweight or obesity. Topline data from that trial is expected in 2027. Novo Nordisk also expects to initiate a phase 2 trial with UBT251 in people with type 2 diabetes in the second half of 2026.
United Biotechnology will present detailed data from the Chinese phase 2 trial at a medical congress later this year. Based on the results of this trial, the company is planning to initiate a phase 3 trial in Chinese patients with overweight or obesity.
About the Chinese phase 2 trial
This randomized, double-blind, placebo-controlled trial enrolled a total of 205 Chinese patients with obesity (BMI ≥ 28.0 kg/m²) or overweight (24.0 kg/m² ≤ BMI < 28.0 kg/m²) with at least one weight-related comorbidity. The baseline mean body weight of the patients was 92.2 kg, with a baseline mean BMI of 33.1 kg/m².
Patients were randomly assigned to receive weekly subcutaneous injections of UBT251 in doses of 2 mg, 4 mg, 6 mg, or placebo for 24 weeks.
The primary endpoint of the trial was the percentage change in body weight from baseline after 24 weeks of treatment.
About UBT251
UBT251 is a long-acting synthetic peptide triple agonist targeting the receptors for GLP-1 (glucagon-like peptide-1), GIP (glucose-dependent insulinotropic polypeptide) and glucagon.
In March 2025, United Biotechnology entered an exclusive license agreement with Novo Nordisk A/S for UBT251. Under the agreement, Novo Nordisk obtained exclusive worldwide rights (excluding Chinese mainland, Hong Kong, Macau, and Taiwan) to develop, manufacture and commercialise UBT251. United Biotechnology retained the rights for UBT251 in Chinese mainland, Hong Kong, Macau and Taiwan.
Hashtag: #UBT251
The issuer is solely responsible for the content of this announcement.
About TUL and United Biotechnology
Founded in 1990, TUL (HKEX: 3933) is mainly engaged in the research and development, production and sales of pharmaceuticals, and ranks among the leading integrated pharmaceutical companies in China. TUL currently boasts seven production bases, covering intermediate products, bulk medicine, finished products, veterinary drugs, empty capsule casings, and medical devices, with the sales networks dotted across nearly 80 countries and regions. United Biotechnology, located in the Guangdong-Macao In-Depth Cooperation Zone in Hengqin, serves as the biopharmaceutical R&D headquarter of TUL. United Biotechnology focuses on the development of high-end biopharmaceuticals to treat major chronic diseases. For more information, please visit www.tul.com.cn.
About Novo Nordisk
Novo Nordisk is a leading global healthcare company, founded in 1923 and headquartered in Denmark. Our purpose is to drive change to defeat serious chronic diseases, built upon our heritage in diabetes. We do so by pioneering scientific breakthroughs, expanding access to our medicines, and working to prevent and ultimately cure disease. Novo Nordisk employs about 68,800 people in 80 countries and markets its products in around 170 countries. For more information, visit novonordisk.com, YouTube.
Media OutReach
SIM GE Prepares Graduates for Singapore’s Evolving Workforce
In Singapore today, employability is no longer defined by academic achievement alone. Employers are looking for graduates who can apply knowledge in real workplace settings, work across cultures, adapt to new technologies and continue learning as industries evolve. This is especially relevant as Singapore’s labour market continues to move towards growth areas such as digitalisation, technology, sustainability, healthcare, business transformation and professional services.
Against this backdrop, Singapore Institute of Management Global Education, or SIM GE, continues to strengthen its role as a private education institution that prepares learners for the demands of today’s workplace and the opportunities of tomorrow’s economy.
Employability begins with industry relevance
For prospective students, one of the biggest considerations when choosing a higher education pathway is whether their studies will remain relevant by the time they graduate. This is particularly important in a job market where roles are changing quickly and where employers increasingly value both technical capability and transferable workplace skills.
SIM GE addresses this by offering a broad range of academic programmes through partnerships with reputable universities from Australia, Europe, the United Kingdom and the United States. These programmes span disciplines such as business, computing, social sciences, aviation, nursing and other applied fields, giving students access to international curricula while studying in Singapore.
This global education model is particularly relevant for Singapore’s open economy. Graduates entering the workforce are expected to understand local business realities while being able to operate in regional and international contexts. By learning from local and international faculty, and studying alongside peers from diverse backgrounds, SIM students are exposed to global perspectives that can support their workplace readiness.
Career support that connects learning to work
Employability also depends on how students translate classroom learning into career action. At SIM GE, career preparation is supported through Career Connect, which provides career workshops, career guidance, résumé reviews, mock interviews, profiling support, internship and job opportunities, as well as career events such as company visits, networking sessions, career talks and fairs.
This structured support is important because many students do not only need a qualification, they also need guidance in understanding industries, articulating their strengths, preparing for interviews and building professional networks. These practical areas can influence how confidently graduates enter the job market.
Through CareerSense, SIM students can also access an integrated online platform to browse and apply for internships, jobs and career events. This helps students take a more proactive approach to career planning while creating a clearer bridge between academic life and employment opportunities.
Real world exposure through internships and traineeships
One of the strongest contributors to graduate employability is exposure to work before graduation. Internships allow students to understand workplace expectations, test their skills in real business scenarios and build confidence before entering full time employment. SIM GE supports this through internships with a range of employers, from SMEs to multinational corporations. Its Work Integrated Learning for Life initiatives and internship related awards further encourage students to gain practical experience and develop holistically across cognitive, interpersonal and applied skills.
For fresh graduates, SIM’s Graduate Traineeship Programme provides structured traineeship opportunities across industries, typically lasting three to six months. The programme is designed to help graduates gain hands on experience, build workplace confidence and develop industry relevant capabilities as they transition into full time employment. This emphasis on work exposure responds directly to a key concern among prospective students, which is whether they will be ready for employment after graduation. By combining academic learning with career guidance, internships and traineeships, SIM GE helps students build not only credentials but also workplace familiarity.
The value of practical exposure is reflected in the experience of Keisha Shevila, a SIM-University of Wollongong Computer Science graduate who secured a Software Engineer role before completing her degree. In sharing her journey, she credited Career Connect with helping her better understand the job search process and preparing her “more confidently for entering the workforce”.
Building future ready graduates through skills and adaptability
The future of work is increasingly shaped by AI, automation, sustainability and cross functional collaboration. In this environment, students need more than role specific knowledge. They need adaptability, communication skills, critical thinking, creativity, cultural awareness and the confidence to keep learning.
SIM GE’s broader student experience supports this development. Beyond academic programmes, students can participate in more than 70 student clubs and co-curricular activities that build leadership, communication and teamwork skills. The EDGE Award, developed in partnership with employers, recognises students’ cumulative achievements across their learning journey and encourages a more holistic approach to personal and professional growth.
SIM GE’s diverse learning environment also plays an important role. With students from more than 50 nationalities, the campus experience provides opportunities for cultural exchange, collaboration and global awareness. These are qualities that are increasingly valuable in multinational and regional workplaces.
Aligning with Singapore’s skills first economy
Singapore’s workforce strategy continues to place strong emphasis on skills, lifelong learning and adaptability. National reports and government agencies have highlighted rising demand in areas linked to the digital, green and care economies, as well as the importance of AI literacy and transferable skills. This makes higher education choices more consequential. Prospective students are not simply choosing a programme. They are choosing a platform for long term career resilience.
SIM GE’s approach aligns with this direction by combining academic pathways, global university partnerships, employability support, industry exposure and continuous skills development. Its graduate outcomes also reflect this emphasis, with SIM reporting a secured employment rate of 81 per cent based on the Private Education Institution Graduate Employment Survey 2024/2025.
Preparing graduates for Singapore today and tomorrow
Employability in Singapore today is shaped by industry relevance, practical exposure and future ready skills. SIM GE’s proposition sits at the intersection of these priorities. For students, this means access to internationally recognised academic pathways, career services, internships, traineeships, employer engagement, student development opportunities and a diverse campus environment. For employers, it means a pool of graduates who have been encouraged to build both knowledge and workplace ready capabilities.
As prospective students consider their higher learning options, the question is no longer only what they can study. It is also how that education will prepare them for the future of work. For SIM GE graduates, the answer lies in an education experience designed not only to support academic achievement but also to develop employable, adaptable and globally minded individuals ready to contribute to Singapore’s evolving economy.
References
- The SIM Advantage – https://www.sim.edu.sg/degrees-diplomas/sim-global-education/sim-advantage
- SIM Career Services – https://www.sim.edu.sg/degrees-diplomas/life-at-sim/career-services
- Achieving the three “Beyond” at individual, industry and institutional levels: Minister Chan Chun Sing at the inaugural SIM Future of Work Series – https://www.sim.edu.sg/news-events/achieving-the-three-beyonds-at-individual-industry-and-institutional-levels
- How One International Student Graduated Career-Ready: Keisha Shevila’s Journey at SIM – https://www.sim.edu.sg/articles-inspirations/how-one-international-student-graduated-career-ready-keisha-shevila-journey-at-sim
- Job Vacancies 2025: Labour demand gradually shifting to growth areas as firms adjust hiring plans – https://www.mom.gov.sg/newsroom/press-releases/2026/0320-job-vacancies-report-2025
- Opening Address by Ms Gan Siow Huang, Minister of State, Ministry of Education for the Launch of the Skills Demand for the Future Economy Report 2025, Marina Bay Sands Expo and Convention Centre – https://www.moe.gov.sg/news/speeches/20250122-opening-address-by-ms-gan-siow-huang-minister-of-state-ministry-of-education-for-the-launch-of-the-skills-demand-for-the-future-economy-report-2025-marina-bay-sands-expo-and-convention-centre
- SDFE 2025 report – https://jobsandskills.skillsfuture.gov.sg/sdfe-2025
Hashtag: #SIMGlobalEducation #SIMGE #GlobalEducation #InternationalDegree #CareerReady #FutureSkills
The issuer is solely responsible for the content of this announcement.
About SIM Global Education
SIM Global Education (SIM GE) is a leading private education institution in Singapore and the region. We offer more than 140 academic programmes ranging from diplomas and graduate diploma programmes to bachelor’s and master’s degree programmes with some of the world’s most reputable universities from Australia, Canada, Europe, United Kingdom, and the United States. SIM GE’s cohort is made up of 17,000 full- and part-time students and adult learners, of which approximately 41% are international students hailing from over 50 countries.
SIM GE’s holistic learning approach and culturally diverse learning environment aim to equip students with knowledge, industry skills and employability competencies, as well as a global perspective to succeed as future leaders in a fast-changing, technologically driven world.
For more information on SIM Global Education, visit www.sim.edu.sg
Media OutReach
Green SM officially launches all-electric ride-hailing service in Kazakhstan
The launch ceremony was held in Almaty with the attendance of Mr. Nguyen Thanh Le, Appointed Ambassador of Viet Nam to Kazakhstan; Mr. Berikbol Shatabayevich Mandibayev, Head of the Department of Entrepreneurship and Investment of Almaty; along with representatives of the Government of Kazakhstan, the Embassy of Vietnam in Kazakhstan, and strategic partners, businesses and organizations across the transportation, energy, technology, finance, infrastructure and service sectors.
In its initial phase, Green SM will operate in Almaty with a fleet of VinFast VF 6 Eco vehicles, an all-electric SUV designed to meet the needs of everyday urban travel. Combining quiet operation, a comfortable cabin, and modern safety features, the VinFast VF 6 Eco is expected to provide residents and visitors in Almaty with a more convenient, reliable, and enjoyable mobility experience.
Alongside its electric vehicle fleet, Green SM continues to invest in the development of its Green Drivers through comprehensive training programs covering operations, safety, and customer service. This forms part of the company’s ongoing efforts to maintain consistent service standards and deliver safe and dependable transportation experiences for users in Kazakhstan.
To celebrate the launch, Green SM is offering a promotion of 26%, up to KZT 2,626 for customers booking rides through the Green SM application. Users in Kazakhstan can now access Green SM services via the Green SM app, available on both the App Store and Google Play.
In parallel with the service launch, Green SM has established partnerships with five strategic partners across the transportation, tourism, technology, and service sectors through the Green Alliance Frontier initiative. The initiative serves as a platform connecting organizations that share a commitment to sustainable development and creating positive impacts for local communities across multiple markets.
Mr. Nguyen Quoc Tuan, Global Chief Executive Officer of GSM, said: “Kazakhstan is a market with strong potential, dynamic growth, and rising expectations for modern services. We come to Kazakhstan with respect for the market, a long-term commitment to investment, and a desire to work alongside local partners in developing high-quality mobility solutions that meet the everyday needs of the community. At Green SM, we believe sustainable growth must be built on trust and meaningful value for society. That is the foundation we hope to build together with our customers, partners, and the people of Kazakhstan in the years ahead.”
Kazakhstan is experiencing the rapid development of modern urban centers alongside rising expectations for quality of life and better services. Green SM’s presence in Kazakhstan reflects the company’s long-term vision of bringing all-electric mobility solutions closer to users in more regions around the world. Green SM enters Kazakhstan with the aspiration of contributing to better mobility experiences for local communities: quieter journeys along busy city streets, more comfortable travel in everyday life, and greater reliability through service standards that are consistently maintained across every trip.
Founded in Vietnam in 2023, Green SM currently operates a green mobility ecosystem across Vietnam, Laos, Indonesia, the Philippines, India, and Kazakhstan. With an all-electric fleet, a technology-driven platform, and consistently applied operational standards, Green SM is steadily expanding its green mobility ecosystem across international markets, with the goal of providing modern, safe, and sustainable transportation solutions for communities around the world.
Hashtag: #GreenSM
The issuer is solely responsible for the content of this announcement.
Media OutReach
Citi Commercial Bank Drives Dialogue on the Future of Business at Annual Executive Summit in Hong Kong
Over 120 business leaders gathered at the summit under the theme “Empowering Growth Through Capital Convergence and Digital Innovation”
HONG KONG SAR – Media OutReach Newswire – 23 June 2026 – The Citi Commercial Bank Hong Kong Executive Summit 2026 concluded on June 16 under the theme “Empowering Growth Through Capital Convergence and Digital Innovation”, bringing together over 120 company founders and C-suite leaders to examine the future of business amid a rapidly evolving global landscape.
The annual flagship forum featured a series of discussions centered on how companies can strategically leverage Hong Kong’s unique strengths to achieve sustainable growth and international expansion.
Gunjan Kalra, Head of Citi Commercial Bank for Japan, Asia North and Australia, and Asia South, said, “Companies today are going global at an unprecedented pace. We are also witnessing the rising global prominence of Asian companies, which are making rapid advances and emerging as industry leaders in areas including AI, technology and innovation, healthcare, advanced manufacturing and clean energy.”
Citi Commercial Bank provides global banking solutions to mid-sized companies that are looking to grow rapidly and expand internationally. “Citi is uniquely positioned to support their growth ambitions, offering integrated treasury and capital solutions in over 90 countries through our integrated global platform, as well as advisory and financing capabilities from our investment banking franchise,” she continued.
According to InvestHK, more than 310 companies had established or expanded operations in Hong Kong as of May 2026, with mainland firms accounting for over half of the total.
Joy Cheng, Head of Citi Commercial Bank for Hong Kong,said, “Hong Kong serves a critical dual role as both the launchpad for Chinese companies pursuing international expansion and a strategic gateway for multinationals deepening their presence in mainland China and the region. We are committed to being the banking partner of choice for fast-growing companies as they scale and grow across borders. Our value proposition lies in our ability to simplify complexity and connect visionary companies to opportunities worldwide through our unparalleled global network.”
Key themes explored at the Hong Kong Executive Summit 2026 included:
- Investing for future growth
- Leveraging Hong Kong’ssuper-connector role for outbound success
- Bridging Hong Kong’s AI and tech landscape with global market opportunities
The summit featured a distinguished line-up of speakers, including:
- Clara Chan, Chief Executive Officer, Hong Kong Investment Corporation Limited
- Evan Chen, Managing Director, FountainVest
- Shang Chuang, Chief Financial Officer, Klook
- CY Guan, Founder & Chief Executive Officer, MOZA Racing
- Jerry Hu,Managing Director, Full Vision Capital
- Wesley Ng, CEO and Co-Founder, CASETiFY
- Jonathan Song, Chief Commercial Officer, Plaza Premium Group
- Andy Wong, Head of Innovation & Technology and Life & Health Sciences, Invest Hong Kong
- Dennis Wong, Co-Founder and Chief Executive Officer, Master Concept
- Queenie Wong, Managing Director, EQT Asia Growth
- Danny Yeung, CEO, Chairman and Co-Founder, Prenetics
- Ethan Yuan,Vice President, International Business, Regional General Manager, APAC North, Alibaba Cloud Intelligence Group
Citi Commercial Bank offers a comprehensive suite of products and solutions, including trade and working capital, treasury and liquidity management, global markets capabilities, capital markets solutions, and advisory services. Citi Commercial Bank serves clients in 12 markets in Asia including Australia, mainland China, Hong Kong, India, Indonesia, Japan, Malaysia, Singapore, South Korea, Taiwan, Thailand, and Vietnam.
Hashtag: #Citi
The issuer is solely responsible for the content of this announcement.
About Citi
Citi is a preeminent banking partner for institutions with cross-border needs, a global leader in wealth management and a valued personal bank in its home market of the United States. Citi does business in more than 180 countries and jurisdictions, providing corporations, governments, investors, institutions and individuals with a broad range of financial products and services.
Additional information may be found atwww.citigroup.com | X:
@Citi | LinkedIn:
www.linkedin.com/company/citi | YouTube:
www.youtube.com/citi | Facebook:
www.facebook.com/citi
-
Feature/OPED6 years agoDavos was Different this year
-
Travel/Tourism10 years ago
Lagos Seals Western Lodge Hotel In Ikorodu
-
Showbiz3 years agoEstranged Lover Releases Videos of Empress Njamah Bathing
-
Banking8 years agoSort Codes of GTBank Branches in Nigeria
-
Economy3 years agoSubsidy Removal: CNG at N130 Per Litre Cheaper Than Petrol—IPMAN
-
Banking3 years agoSort Codes of UBA Branches in Nigeria
-
Banking3 years agoFirst Bank Announces Planned Downtime
-
Sports3 years agoHighest Paid Nigerian Footballer – How Much Do Nigerian Footballers Earn


