Health
COVID-19-Related Deaths Fewer in Africa—WHO
By Adedapo Adesanya
A new World Health Organisation (WHO) pandemic assessment has found out that despite an 83 per cent surge in new COVID-19 cases during the past week in Africa, driven by the Delta and the Omicron variants, fewer deaths have been recorded than in the previous surges.
It, however, warned that more waves could be building as updated forecasts warn that the continent may not reach 70 per cent vaccine coverage until August 2024.
According to the report, Africa recorded more than 196,000 new cases for the week ending December 12, up from around 107,000 in the previous week, bringing the total cumulative number of recorded cases during the pandemic to 8.9 million.
The number of new COVID-19 cases is currently doubling every five days, the shortest reported this year while the speed of the spread is fast, deaths remain low and even dropped by 19 per cent last week compared with the previous week.
There were a little over 3,000 COVID-19-related deaths reported during the first three weeks of the current pandemic wave, which is Africa’s fourth.
WHO explained that about half as many cases were reported in the same time frame during the third wave which was fuelled by the Delta variant.
This upsurge in new cases coupled with low hospitalizations is particularly marked in South Africa which has experienced a 66 per cent rise in new cases during the past seven days compared with the previous seven days.
It noted that hospitalizations have increased by 67 per cent in the past seven days, the bed occupancy rate for Intensive Care Units remains low at 7.5 per cent with 14 per cent of the hospitalized patients receiving supplemental oxygen.
Though the deaths also remain low, WHO warned that the data should be interpreted with caution as the pattern may change in the coming weeks.
“We are cautiously optimistic that deaths and severe illness will remain low in the current wave, but slow vaccine rollout in Africa means both will be much higher than they should be,” said Dr Matshidiso Moeti, WHO Regional Director for Africa.
“We’ve known for quite some time now that new variants like Beta, Delta or Omicron could regularly emerge to spark new outbreaks globally, but vaccine-deprived regions like Africa will be especially vulnerable.”
Vaccination coverage remains highly variable across the region. As of 13 December, only 20 African countries had vaccinated at least 10 per cent of their population—the global target WHO had set for September 2021.
Only six countries have hit the year-end target of fully vaccinating 40 per cent of their population, while only two countries—Mauritius and Seychelles—have reached the 70 per cent coverage seen as essential for controlling the pandemic.
At the current pace, WHO estimates that it will take until May of 2022 before Africa reaches 40 per cent coverage and August 2024 before it reaches the 70 per cent mark.
“In a world where Africa had the doses and support to vaccinate 70 per cent of its population by the end of 2021—a level many wealthy countries have achieved—we probably would be seeing tens of thousands of fewer deaths from COVID-19 next year.
“But we can still save many lives if we can accelerate the pace of vaccination in early 2022,” he added.
WHO data show that 53 African countries have initiated vaccination programmes, which have administered a total of 264 million doses (or 61 per cent of doses received).
Fully vaccinating 70 per cent of Africans requires about 1.6 billion more doses and strengthened efforts to increase vaccine demand.
Dr Moeti added that, “We’re at a pivotal moment in this pandemic where complacency is the enemy. With supplies starting to increase we now must intensify our focus on other barriers to vaccination. They include lack of funding, equipment, healthcare workers and cold chain capacity along with tackling vaccine hesitancy.”
According to the WHO Africa COVID-19 readiness dashboard, of the 34 countries that have submitted complete data, 28 countries (80 per cent) have engaged provinces and districts in preparations for vaccinations; 32 countries (91 per cent) have conducted national training initiatives, and 29 countries (82 per cent) have trained district vaccinators and volunteers.
To increase vaccination coverage, WHO is encouraging countries to move vaccination sites beyond health facilities and main cities and implement community-centred approaches. In an analysis of data collected from 40 countries, six countries confirmed having districts with no vaccination sites.
Meanwhile, Africa’s vaccine challenges are being compounded by Omicron-related travel bans.
Globally, there have been more than 2700 Omicron cases reported in 59 countries, including 11 African countries that account for about 33 per cent of the total cases.
However, Africa’s share is steadily dropping, and South Africa no longer leads the world in Omicron cases. Yet more than 70 countries continue to impose travel bans mainly targeting African countries.
In addition to vaccination coverage, WHO’s 2022 COVID-19 strategy for Africa includes a strong focus on surveillance aimed at increasing case detection, strengthening genomic surveillance to track new variants of concern as well as country capacity for appropriate case management including home-based isolation and care, and guarding against COVID-19 with key preventive measures amidst reduced risk perception.
Health
Resident Doctors Suspend Proposed Indefinite Strike
By Adedapo Adesanya
The Nigerian Association of Resident Doctors (NARD) has suspended its planned indefinite strike following the federal government’s reversal of the implementation of the reviewed Professional Allowance Table (PAT) and renewed assurances on outstanding payments.
The decision was announced in a communiqué issued at the end of an emergency National Executive Council (NEC) meeting held virtually on Saturday.
NARD had earlier resolved to embark on a total and indefinite strike over the government’s suspension of the reviewed allowance structure and other unresolved welfare concerns affecting resident doctors nationwide.
However, the association said it reconsidered its position after reviewing the outcomes of high-level engagements with key government officials and health-sector stakeholders.
According to the communiqué signed by NARD President, Dr Mohammad Usman Suleiman; Secretary-General, Dr Shuaibu Ibrahim; and Publicity and Social Secretary, Dr Abdulmajid Yahya Ibrahim, the Federal Government has now reversed its earlier decision on the allowance table.
“The NEC observed that the earlier decision to halt the implementation of the reviewed Professional Allowance Table (PAT) has been reversed, with implementation expected to reflect in the April salary and beyond,” the statement read.
The association also noted the government’s renewed commitment to settling outstanding promotion and salary arrears owed to resident doctors in affected institutions.
In addition, NARD said initial approval had been secured for the 2026 Medical Residency Training Fund (MRTF), with assurances that the disbursement process would be concluded.
“The NEC observed that the Budget Office has indicated its readiness to commence the process for the payment of the outstanding nineteen months’ arrears of the Professional Allowance,” the communiqué added.
Despite the progress, the doctors expressed concern about the continued delay in paying house officers’ salaries and called for urgent action to address the issue.
Following its deliberations, the NEC demanded the sustained implementation of the reviewed allowance structure, the prompt payment of all outstanding arrears, and the expedited disbursement of the residency training fund.
It also called for the immediate commencement of the process to clear the 19-month arrears and the convening of an urgent stakeholders’ meeting to resolve delays affecting house officers’ salaries.
“In light of the above developments, the NEC resolves to suspend the proposed total, indefinite, and comprehensive strike action, with a review of progress to be undertaken at the May Ordinary General Meeting (OGM) in Kano,” the statement said.
NARD expressed appreciation to President Bola Tinubu, Vice President Kashim Shettima, and several ministers, government agencies, and stakeholders for their interventions in resolving the dispute.
Health
Over 1.5 million Nigerian Children Living With Sickle Cell Disease—Report
By Modupe Gbadeyanka
More than 1.5 million children under the age of 15 are living with sickle cell disease in Nigeria, a new international study published in The Lancet Child & Adolescent Health, one of the world’s leading medical journals, has revealed.
In the report made available to Business Post, it was disclosed that Nigeria carries the highest burden of disease globally, far exceeding other high-burden countries such as the Democratic Republic of the Congo and Ethiopia.
The findings highlight both the scale of the challenge in Nigeria and the opportunity for the country to lead Africa in tackling one of the most preventable causes of childhood illness and death.
The study shows that nearly nine million children across sub-Saharan Africa are living with sickle cell disease in 2023, including around 1.17 million infants and 2.75 million children under five, who face the highest risk of early death without treatment.
Sickle cell disease is an inherited blood disorder present at birth. With early diagnosis and access to simple, low-cost interventions such as newborn screening, penicillin prophylaxis, routine vaccinations, malaria prevention, and hydroxyurea, most complications and deaths can be prevented.
However, in Nigeria, access to these essential services remains limited. Many children are only diagnosed after severe and avoidable complications, while others are never diagnosed at all, contributing to high levels of preventable illness and early childhood deaths.
The researchers emphasise that strengthening Nigeria’s health system response will be critical. This includes expanding newborn screening programmes, improving access to essential medicines, and integrating sickle cell care into primary healthcare services.
They called for urgent and coordinated action across government, health institutions, and development partners, including expanding newborn screening programmes, improving access to essential medicines and vaccines, and embedding sickle cell care within primary healthcare services.
The researchers, led by Professor Davies Adeloye, Professor of Public Health at Teesside University, United Kingdom, and Director of the International Society of Global Health (ISoGH), also called for increased domestic investment, supported by international partnerships, as well as stronger data systems to improve surveillance and guide policy decisions.
They concluded that even modest improvements in early-life screening and treatment in high-burden countries like Nigeria could transform child survival and significantly reduce preventable deaths.
“Nigeria now stands at the centre of the global sickle cell crisis. With over 1.5 million children affected, the scale is enormous, but so is the opportunity to act. We already know what works. Newborn screening and early treatment are effective, affordable, and can be delivered through existing health systems.
“If Nigeria prioritises sickle cell disease within its national health agenda and integrates care into routine maternal and child health services, we could save hundreds of thousands of young lives and significantly reduce avoidable deaths.” Professor Adeloye noted.
It was learned that the study analysed data from 40 studies across 22 African countries to produce the most comprehensive country-level estimates of childhood sickle cell disease to date.
Health
Helical Secures $10m Funding Package for Expansion
By Dipo Olowookere
A $10 million capital has been raised by Helical to support expansion across more top-20 pharma programmes and growth of its deployed science engineering team.
The firm will also use the money to build the compounding evidence layer that improves performance across diseases, as its mission is to make every scientist able to test hypotheses at the speed of inference and to turn in-silico discovery into a reliable engine for R&D throughput.
The funding package was from redalpine, Gradient, BoxGroup, Frst and notable angels, including Aidan Gomez (CEO Cohere), Clement Delangue (CEO HuggingFace) and Mario Goetze (pro soccer player).
Helical has a product known as the virtual AI lab for pharma, an application layer that turns biological foundation models into decision-ready, reproducible in-silico discovery workflows.
The platform has two product surfaces — the Virtual Lab for biologists and translational scientists, and the Model Factory for ML engineers and data scientists — built on the same data, the same models, and the same results.
By putting both sides in the same system, Helical closes the gap between computational predictions and biological decision-making, so teams that traditionally worked in silos can collaborate on the same evidence.
Helical was founded in early 2024. It was created by three school friends who took different paths to the same problem.
Rick Schneider built tech at Amazon and later helped the German enterprise Celonis scale in France and Japan. Maxime Allard led data science teams at IBM before pursuing a PhD focused on reinforcement learning and robotics. Mathieu Klop became a cardiologist and genomics researcher.
When bio foundation models emerged, the trio saw the chance to build the missing application layer that would let pharma teams move from model experimentation to reproducible, production discovery.
“The models alone don’t discover drugs. The system does. Pharma teams need a system that turns foundation models into workflows scientists can run, validate, and defend.
“We built Helical to make in-silico science reproducible at pharma scale, so teams can go from hypothesis to decision in days instead of months,” the co-founder of Helical, Mr Rick Schneider, said.
“We are at a unique point in time where biological foundation models and general language reasoning models are converging.
“We backed Helical because we strongly believe they have what it takes to build the pharma AI orchestration platform that will drive this transition from siloed AI models to integrated virtual AI labs,” the General Partner at redalpine, Mr Daniel Graf, stated.
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