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AuctuCel launches AuctuPrime to reduce biological variability in cell therapy manufacturing

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Chemically defined medium removes animal serum and human platelet supplements as Malaysia and Singapore strengthen advanced therapy capabilities

SINGAPORE – Media OutReach Newswire – 4 August 2026 –Singapore is estimated to record approximately 19,290 new cancer cases in 2024, underscoring the growing demand for advanced treatment options and the manufacturing systems needed to produce them consistently. As cell therapies move from research towards clinical use, the reliability of every raw material used in production becomes increasingly important.

AuctuCel Pte Ltd, a Singapore biotechnology company specialising in AI-powered bioprocess technologies, today announced the launch of AuctuPrime, a next-generation chemically defined cell culture medium developed in collaboration with Sperikon. The formulation is designed to remove dependence on both animal serum and donor-derived human platelet supplements during cell therapy manufacturing.

The launch comes as both markets continue to deepen their advanced therapy ecosystems. The Singapore Economic Development Board reported that the country saw a fourfold increase in locally incorporated biotechnology companies since 2015. In Malaysia, the National Pharmaceutical Regulatory Agency issued updated cell and gene therapy product guidance in September 2025, including revised Good Manufacturing Practice requirements. As more research moves towards clinical translation, the reliability and traceability of manufacturing inputs are receiving greater attention.

A less visible bottleneck in cell therapy

Cell therapies are advancing across cancer, autoimmune disease and regenerative medicine, but manufacturing remains one of the major barriers to wider clinical and commercial adoption. Many conventional culture processes still use animal serum or platelet-derived supplements from human donors. These biological materials can vary between batches and may introduce additional sourcing, testing and documentation requirements.

AuctuPrime replaces these supplements with a fully chemically defined formulation. By giving researchers and manufacturers clearer control over what enters the process, it is intended to provide a more reproducible foundation for scale-up from laboratory research to clinical and commercial manufacturing.

The formulation is designed to support:

* Elimination of animal serum and human platelet supplements

* Reduced batch-to-batch variability in the culture process

* Lower dependence on donor-derived biological raw materials

* Greater supply chain resilience through chemically defined inputs

* More consistent scale-up and technology transfer across manufacturing stages

* A xeno-free approach for regenerative medicine and cell therapy workflowsWhy the manufacturing medium matters to patients

“Culture medium is not the therapy itself, but it can influence how reliably cells are produced. By removing animal serum and human platelet supplements, AuctuPrime gives researchers and manufacturers greater control over the process, helping to reduce variability and prepare for larger-scale production.” said Dr Zach Pang, Co-founder and Chief Scientific Officer of AuctuCel.

Supporting Singapore’s advanced therapy ecosystem

Singapore is strengthening its position as a regional hub for advanced therapies, supported by its universities, hospitals, research institutions and biotechnology companies. These organisations are building capabilities that connect early-stage research with regulated manufacturing and future clinical applications. Chemically defined media can support this progress by reducing reliance on variable biological inputs and enabling processes to be reproduced more consistently across local research and manufacturing facilities.

Singapore’s continued progress in regenerative medicine will depend not only on scientific breakthroughs, but also on the ability to manufacture therapies safely, consistently and at scale. AuctuPrime represents an important step towards building a more reproducible manufacturing platform and can support local research and industry teams as they prepare for future clinical and commercial demand,” said Dr Chee Wai Fhu, Chief Executive Officer of AuctuCel.

For the wider region, stronger manufacturing foundations also matter for healthcare resilience. Cell therapies are complex products with demanding quality requirements, and the ability to manufacture them consistently will shape how quickly promising research can progress towards clinical use.

“The future of regenerative medicine depends not only on scientific breakthroughs, but on our ability to manufacture these therapies safely, consistently and at scale,” said Dr Chee Wai Fhu, Chief Executive Officer of AuctuCel. “AuctuPrime is an important step towards a more reproducible manufacturing platform. By removing dependence on animal serum and human platelet supplements, we hope to help researchers and manufacturers build processes that are better prepared for future clinical and commercial demand.”

Regional collaboration behind the launch

AuctuPrime was developed through a collaboration between AuctuCel and Sperikon, combining AuctuCel’s bioprocess and culture media expertise with Sperikon’s experience in regenerative medicine and cell therapy development.

Behind every cell therapy breakthrough is a production process that must work repeatedly, not only once. Improving that process is one of the practical steps needed to bring the next generation of therapies closer to the patients who may benefit from them.

Notes to editors

A chemically defined medium is a formulation in which the components and their concentrations are known and controlled. In this context, xeno-free means the formulation does not rely on animal-derived materials. AuctuPrime is a manufacturing input used during cell culture and is not itself a cell therapy product.

Hashtag: #AuctuCel

The issuer is solely responsible for the content of this announcement.

About AuctuCel

AuctuCel is a Singapore-based biotechnology company spun out of A*STAR’s Bioprocessing Technology Institute. The company develops AI-powered bioprocess technologies and ready-to-use culture media solutions that help biotechnology and cell therapy companies improve manufacturing consistency, productivity and scalability. By combining advanced modelling, scientific expertise and bioprocess innovation, AuctuCel supports the translation of research into commercially viable biomanufacturing. The company has active operations and partnerships across Singapore, Malaysia and the wider Asian region.

About Sperikon

Sperikon is a biotechnology company focused on regenerative medicine, cell culture technologies and translational research. The company works with academic institutions and industry partners to develop scalable solutions that support the clinical and commercial adoption of advanced cell therapies. Through its collaboration with AuctuCel, Sperikon contributes to the development of next-generation chemically defined manufacturing platforms.

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Heartland 66 Accelerates Retail Transformation with the Launch of First-to-Market Korean Trend Zone and edgestreet Concept Space

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Strategic 10,400 sq. m. transformation brings 150+ fashion and lifestyle brands to Central China

WUHAN, CHINA & HONG KONG SAR – Media OutReach Newswire – 4 August 2026 – Heartland 66 in Wuhan, under Hang Lung Properties Limited (SEHK stock code: 00101) (“Hang Lung” or the “Company”), is expanding its new-generation, differentiated retail mix and customer experience offerings through the launch of Central China’s first curated 24KR Korean Trend Zone and edgestreet Concept Space. Building on the Heartland 66’s premium positioning, the two areas bring together Korean Wave culture, contemporary fashion, new-to-market brand launches, vibrant social spaces, and immersive experiences – forming part of Heartland 66’s transformation from a traditional retail destination into a trendy lifestyle hub, while contributing to the development of Wuhan’s retail sector.

24KR Korean Trend Zone, inspired by Seongsu-dong in Seoul, brings together more than 100 trendy Korean brands offering contemporary fashion, footwear and accessories, as well as food and coffee.

Launched between June and July, the 24KR Korean Trend Zone and “Greenhouse by edgestreet,” together spanning approximately 10,400 sq. m., feature a lineup of more than 150 brands. The 24KR Zone captures the contemporary Korean Wave that resonates with new-generation consumers and enriches the shopping experience. “Greenhouse”, meanwhile, is a concept space developed by edgestreet, centered on a greenhouse-inspired botanical theme and offering a diverse mix of design, aesthetics, home living and pet lifestyles. It blends modernfashion, lifestyle aesthetics and social interaction, deepening engagement with emerging customer segments. Among the first batch of brands unveiled, 24KR introduces 11 brands making their China debut and 15 making their Central China debut, while “Greenhouse” brings 20 brands opening their first stores in Wuhan.

"Greenhouse by edgestreet" focuses on designer brands, lifestyle and home living offerings, and pet lifestyle brands favored by new-generation customers, creating a stylish, warm and welcoming aesthetic space that delivers a "greenhouse experience."
“Greenhouse by edgestreet” focuses on designer brands, lifestyle and home living offerings, and pet lifestyle brands favored by new-generation customers, creating a stylish, warm and welcoming aesthetic space that delivers a “greenhouse experience.”

Such initiatives support Wuhan’s goal of accelerating its development into a forward-thinking city and an international consumption center. As a major transportation, education and commercial hub in Central China, Wuhan continues to attract university graduates seeking employment and entrepreneurship, as well as young talent from neighboring provinces who help to fuel local consumption. Heartland 66 aims to inject more emerging consumption experiences and commercial vitality into the local market.

Ms. Veronica Chan, Director – Mainland Business Operation, Hang Lung Properties, said, “Heartland 66 is actively introducing curated fashion and lifestyle offerings in response to the evolving consumer preferences. By providing a rich and diverse range of choices, we are creating placemaking destinations that foster a strong sense of community. As a commercial landmark in Wuhan, we will continue to strengthen our differentiated positioning, contribute to the city’s development as an international consumption center, and help stimulate consumer vitality.”

Mr. Harvey Ye, General Manager of Heartland 66, said, “The successive launch of 24KR Korean Trend Zone and ‘Greenhouse by edgestreet’ marks a firm step forward in engaging younger consumers and driving the revitalization and upgrading of our commercial spaces. On its opening day, the 24KR Zone lifted footfall by more than 50% year-on-year. ‘Greenhouse’, which followed shortly after, also drew a strong market response. Both underscore the powerful potential of the emerging consumer market and the surging economic vitality of Central China.”

Appendix — Details of the 24KR Korean Trend Zone and “Greenhouse by edgestreet”

Item 24KR Korean Trend Zone “Greenhouse by edgestreet”
Location in Heartland 66, Wuhan B1, East Zone L3, East Zone
Area Approximately 2,400 sq. m. Approximately 8,000 sq. m.
Positioning Contemporary Korean fashion and trendy lifestyle Curated designer brands and quality lifestyle offerings
Brand categories Trendy fashion, footwear and accessories, cosmetics and fragrances, designer toys, food and coffee Designer brands, lifestyle and home living offerings, pet lifestyle brands
Number of brands More than 100 trendy and creative Korean brands More than 50 emerging international brands
First-in-market highlights First batch: 11 China-debut and 15 Central China-debut brands, including FANCY CLUB, ZAENIO, IST KUNST, BLACKPURPLE and LAZY First batch: 20 first-in-Wuhan brands, including THE WAREHOUSE by SHOWROOM SHANGHAI, HiOneOne, DOROQ, ARTICLE NO., and D&L Pets Department Store
Design concept Inspired by Seongsu-dong in Seoul, incorporating Korean streetscape elements, tactile material textures, and layered urban details Centered on “Lifestyle Inspiration × Greenhouse Ecology × Artistic Aesthetics,” using light, shadow and greenery to create a natural and open spatial experience

Hashtag: #HangLungProperties

The issuer is solely responsible for the content of this announcement.

About Hang Lung Properties

Hang Lung Properties Limited (SEHK stock code: 00101) creates compelling spaces that enrich lives. Headquartered in Hong Kong and Shanghai, the Company manages a portfolio of over 3.6 million square meters of retail, office, residential, and hotel properties across Hong Kong and the Chinese Mainland.

The Company’s diverse portfolio in Hong Kong includes office towers and malls in prime districts, as well as luxury residential developments in prestigious areas. In the Chinese Mainland, under the signature “66” brand, the Company’s mixed-use and retail developments are regarded as premium landmarks, strategically located in the hearts of key cities of Shanghai, Shenyang, Jinan, Wuxi, Tianjin, Dalian, Kunming, Wuhan, and Hangzhou.

The Company is recognized for pioneering sustainability in the real estate industry, with an MSCI ESG rating of AA and inclusion on CDP “A List” for Climate Change. The Company powers 90% of its operating properties in the Chinese Mainland with renewable energy, with a net-zero commitment by 2050.

At Hang Lung Properties – We Do It Well.

For more information, please visit https://www.hanglung.com.

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Vinhomes’ 6,200-Hectare Ha Long Bay Project: Evolving the Concept of Urban Scale

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HA LONG, VIETNAM – Media OutReach Newswire – 4 August 2026 – Vinhomes has outlined the master plan for Vinhomes Global Gate Ha Long, an integrated urban development spanning approximately 6,200 hectares beside the UNESCO-listed Ha Long Bay. It is the company’s largest urban development to date, marking a shift in how success in city-building is measured: not by the size of the land developed, but by the value every hectare delivers to the people who live there.

An illustration of Vinhomes Global Gate Ha Long’s master plan.

For decades, the size of a master planned community has been one of the industry’s clearest measures of ambition. Across many markets, developments spanning 2,500 acres or more are regarded as large scale projects, distinguished by their mix of housing, retail, schools, parks and lifestyle amenities (1).

Today, as cities confront mounting pressure from climate change, population growth and changing patterns of mobility, urban development is being judged by a different standard. The OECD notes that future cities must do more than expand. They must connect people to jobs and services, strengthen climate resilience and integrate nature into the fabric of urban infrastructure (2).

Positioned along the Hanoi – Hai Phong – Quang Ninh Expressway, at the intersection of northern Vietnam’s tourism, industrial and logistics corridors, Vinhomes Global Gate Ha Long is planned not as a residential complex but as a fully integrated city, bringing together world-class housing, public services, commerce and ecological infrastructure within a single connected environment. The project represents Vinhomes’ most comprehensive urban vision to date, extending two decades of evolution from landmark residential projects to fully integrated townships.

A City Engineered for Connectivity and Daily Convenience

At the core of the master plan is the principle of an integrated urban ecosystem, designed to shorten the distance between where people live, work, learn and access essential services. Transportation, education, healthcare, commerce and hospitality are embedded within a single, unified environment.

Reinforcing this connectivity is the project’s location adjacent to the future depot station of the Hanoi–Quang Ninh high-speed railway, which is expected to connect residents to the capital in approximately 23 minutes, reshaping regional mobility and enabling a single daily commute between the intensity of metropolitan Hanoi and the UNESCO World Heritage landscape of Ha Long Bay.

Residents will also enjoy uninterrupted views of Ha Long Bay itself, alongside clean air, expansive waterfronts and exceptional ecological quality. Residential offerings span villas, townhouses, shophouses and high-rise apartments across six major districts.

Embedding Sustainability and World-Class Amenities

Environmental regeneration underpins the development at scale. More than 2,500 hectares are dedicated to green spaces, water bodies and mangrove landscapes, including 680 hectares of naturally filtered seawater, approximately 200 kilometers of coastline and the 660-hectare Globe Ha Long Forest Park. Together, these ecological assets are designed to support biodiversity, strengthen climate resilience and foster healthier living conditions, forming the core of Vinhomes’ ESG++ vision for regenerative urban development.

The city is organized around interconnected ecosystems. Culture and entertainment feature a 60,000-seat outdoor waterfront venue, the 3,000-seat Wonder Theatre, an 81-hectare VinWonders destination featuring what is planned to be the world’s largest aquarium park, an international convention center for more than 4,500 guests, and an 18.5-hectare Vietnamese Cultural and Culinary Village.

Hospitality and leisure offerings include internationally managed luxury hotels and resorts, integrated casino facilities, a 950-hectare golf complex comprising 12 courses, an 800-hectare mangrove recreational park, and Wonder Marina, which provides direct access to Ha Long Bay.

Commerce and lifestyle amenities are centered around Vincom Mega Mall, premium outlet shopping, Vincom Collection retail streets and dedicated lifestyle destinations, creating a 24-hour retail and dining environment.

Sports and wellness infrastructure includes Vietnam’s first purpose-built Sports District, spanning 13.3 hectares, a professional sports academy, and more than 50 kilometers of cycling routes woven throughout the city.

Health and education needs are met by the 14-hectare Vinmec Cleveland Clinic International Hospital; Vin New Horizon, Vietnam’s largest senior living center; Golden Residence retirement villas; Vinschool campuses; an American international school; and Wonder Young Hub, a dedicated center for youth development.

Anchoring the city’s economic future is a new central business district featuring office towers of 30 to 45 stories, designed to attract domestic and international businesses and reinforce Ha Long’s role as a major economic and financial hub.

Setting a New Standard for Future Urban Development

Vinhomes Global Gate Ha Long has been planned in alignment with ISO 37125, the latest international guidance for sustainable urban development, while incorporating Vingroup’s ESG++ approach, extending beyond environmental protection to encompass ecological regeneration, resource efficiency, digital governance, resilient infrastructure and long-term community wellbeing.

Smart technologies, including artificial intelligence, Internet of Things applications and data-driven urban management, are intended to optimize city operations alongside green mobility systems and efficient public infrastructure.

Guided by three core principles, connectivity, regeneration and excellence, the project seeks to demonstrate how mobility, environmental stewardship, public services, commerce and culture can function within a single planning framework. Through this approach, Vinhomes underlines its commitment to developing integrated urban environments designed for long-term sustainability.

1. https://www.newhomesource.com/learn/all-about-master-planned-communities/
2. https://www.oecd.org/content/dam/oecd/en/publications/reports/2025/12/integrated-urban-policy-to-achieve-the-sdgs_e1bb165d/ada07311-en.pdf

Hashtag: #Vinhomes

The issuer is solely responsible for the content of this announcement.

About Vinhomes

Vinhomes is Vietnam’s largest residential real estate and integrated township developer. The company pioneers the development of synchronized, modern large-scale townships, delivering premium living standards and unlocking sustainable investment opportunities for domestic and international clients.

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2026 World Manufacturing Convention Releases Teaser, Extending a Global Invitation to Innovate Together

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HEFEI, CHINA –

The 2026 World Manufacturing Convention will be held from September 20 to 23 at the Hefei Binhu International Convention and Exhibition Center in Hefei, Anhui, China. During the event, government leaders, representatives from international organizations, manufacturing executives, experts, and scholars from around the world will gather in Hefei to explore new pathways for high-quality development in manufacturing and share new opportunities for industrial cooperation.

Centered on the theme “Intelligent Manufacturing, Better Future,” the 2026 World Manufacturing Convention will further enhance its international and professional appeal. The Convention is expected to welcome approximately 1,000 distinguished guests, including around 500 overseas representatives, and will feature a series of events such as the opening ceremony and keynote speeches, major project matchmaking events, exhibitions showcasing manufacturing achievements, and innovation matchmaking programs for future industries.

During the Convention, a range of key activities will focus on areas including intelligent manufacturing, artificial intelligence, and future industries. These will include the Forum on Building China into a Manufacturing Power, the China-Europe International Manufacturing Cooperation Matchmaking Conference, and matchmaking activities for the digital and intelligent transformation of the manufacturing sector, further facilitating global collaboration in manufacturing resources, technologies, and projects.

The release of the teaser marks the full launch of the promotional campaign for the 2026 World Manufacturing Convention. With an open and forward-looking approach, Anhui is embracing the global wave of manufacturing transformation, driving industrial upgrading through technological innovation, and extending a global invitation for intelligent manufacturing collaboration, welcoming partners from around the world to join this future-oriented gathering of the manufacturing industry.

For more video information, please visit:
https://www.youtube.com/watch?v=ENC-yg6zfEk

Hashtag: #WorldManufacturingConvention

The issuer is solely responsible for the content of this announcement.

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