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Dr. Terence Tan, Medical Director of Halley Body Slimming Clinic, Shares Insights on the Evolving Role of Doctors in Medical Weight Management and GLP-1 RAs at Symposium
The Growing Role of GLP-1 Therapies in Clinical Practice
This continuing medical education (CME) session addressed a clear shift in clinical practice, where more patients are actively seeking medical support for weight loss and management. They are increasingly arriving informed, often asking specifically about newer medications and expecting clear guidance on suitability and outcomes.
GLP-1 RAs, including semaglutide and tirzepatide, have contributed to this change. These medications work by influencing appetite and satiety, helping to reduce overall caloric intake. Semaglutide acts on GLP-1 receptors to regulate hunger, while tirzepatide targets both GLP-1 and GIP pathways, offering an additional mechanism that supports weight reduction and metabolic control.
As a result, consultations are becoming more complex. Patients may have expectations shaped by online information or anecdotal experiences, making it important for doctors to guide discussions based on clinical suitability rather than demand alone.
“This shift calls for a more structured and informed approach,” said Dr. Tan. “Doctors must take a more active role in assessing patients, setting expectations, and ensuring that treatment is used appropriately as part of a broader weight management strategy.”
Looking Beyond BMI When Determining Treatment Suitability
Dr. Tan emphasised that successful use of GLP-1 RAs begins with careful patient selection. Clinical guidelines typically recommend treatment for individuals with a body mass index (BMI) of 30 kg/m² or higher, or 27 kg/m² with at least one weight-related condition such as hypertension or dyslipidaemia.
However, beyond these criteria, real-world decision-making often requires a more nuanced approach. Doctors should work to assess each patient’s broader context, including their occupation, psychological readiness, and ability to commit to follow-up. For example, many patients in GP settings are working adults who are motivated to lose weight but may struggle with consistency. For this group, medical support can offer a more practical pathway than lifestyle changes or advice.
A Structured Approach to GLP-1 Therapy in General Practice
A key theme of Dr. Tan’s presentation was that GLP-1 therapy should not be treated as a one-off prescription, but as part of a structured care process. He outlined the importance of setting clear goals from the outset, guiding patients towards gradual and realistic weight loss. Early targets may involve a reduction of 1.5 to 2 kilograms per month, followed by a slower and more sustainable pace.
Weight loss injections are introduced gradually, with doctors adjusting the dose over time while monitoring patients’ responses. During this period, patients may experience side effects such as nausea or fatigue, particularly in the early stages, which are reviewed during follow-up visits. Clinics should also schedule monthly reviews at the start, before spacing them out based on progress.
Within the clinic, staff play an active role in supporting treatment. Beyond administrative duties, they guide patients through injection techniques, provide counselling, and reinforce key instructions throughout the process. They should also share educational materials and structured programmes to help patients stay more consistent and engaged with treatment.
Together, these elements form a coordinated care pathway in which doctors actively guide patients through each stage of treatment rather than relying solely on medication.
Reinforcing Lifestyle and Behavioural Change Alongside Treatment
While GLP-1 RAs support weight loss, Dr. Tan emphasised that they do not replace lifestyle change. Dietary adjustments, including reduced-calorie approaches and structured eating patterns such as time-restricted eating, remain important. Physical activity also plays a key role, increasing energy expenditure and maintaining a caloric deficit, thereby supporting sustained weight loss over time.
He also highlighted the importance of behavioural factors. Encouraging patient commitment and involving family or social support systems can strengthen adherence and improve long-term outcomes. Weight management, he noted, requires attention to both biological and behavioural factors.
Maintaining Long-Term Weight Loss Outcomes
Weight management does not end once initial targets are achieved. Dr. Tan noted that maintaining weight loss can be challenging, particularly for patients who have experienced significant reductions. While motivation plays a role, physiological factors such as appetite regulation can make long-term maintenance difficult.
Patients who adopt consistent lifestyle changes, including regular physical activity and more mindful food choices, may sustain their results over time. For others, ongoing or adjusted treatment may be considered. Options can include continuing medication, reducing the dosage, or using treatment periodically, depending on individual needs and preferences.
At the same time, doctors should inform their patients about the possibility of a weight-loss plateau, a common and expected phase of treatment. Even in such cases, continued management may still provide meaningful health benefits.
Addressing Real-World Challenges in Clinical Implementation
Dr. Tan also addressed practical challenges in adopting GLP-1 RAs. Cost remains a key consideration, particularly in the absence of broader subsidies. However, as other types of weight-loss medication become more widely available and competition grows, GLP-1 therapies may gradually become more affordable.
Patient awareness is another factor. Some individuals may not be familiar with these treatments, while others may have concerns about side effects. Dr. Tan emphasised that these concerns are best addressed through doctor-led consultations, where treatment decisions are guided by an individual assessment of benefits and risks.
Weight management is also influenced by underlying biological factors. Differences in appetite regulation and satiety can affect how individuals respond to food intake, which partly explains why maintaining weight loss can be challenging. According to Dr. Tan, some patients are able to sustain results through increased physical activity and more mindful eating, while others may find it difficult to maintain their weight after stopping medication.
A Shift Towards More Comprehensive, Long-Term Weight Management
As GLP-1 therapies become more widely used in Singapore, weight management is increasingly being approached as an ongoing clinical discipline rather than a short-term intervention. This shift places greater emphasis on continuity of care, patient education, and the doctors’ role in guiding treatment decisions over time.
“GLP-1 therapies are changing how patients approach weight loss, but medication alone is not the solution,” said Dr. Tan. “As doctors, it is our responsibility to ensure that patients are properly assessed, supported, and followed up throughout their weight management journey.”
To learn more about Halley Body Slimming Clinic’s approach to weight management, visit their website.
Hashtag: #HalleyBodySlimmingClinic #GLP1RA #Glucagon-LikePeptide-1ReceptorAgonists #weightlossmanagement
The issuer is solely responsible for the content of this announcement.
About Halley Body Slimming Clinic
Halley Body Slimming Clinic is a Singapore-based clinic offering doctor-led treatments focused on weight loss, 
body contouring, skin firming, and more. The clinic takes a consultative approach, where each patient undergoes a clinical assessment before receiving a personalised treatment plan tailored to their goals and needs. Services include prescription weight-loss medications, along with non-invasive fat-reduction and body-contouring treatments using CoolSculpting Elite and Vanquish to address specific areas. By combining medical interventions with regular follow-up and patient education, the clinic supports individuals through different phases of their weight management journey.
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MarsLab Introduces Singapore-Based AI Inference Infrastructure Roadmap for Enterprise and Edge Deployment
MarsLab outlines a system-first approach to AI inference infrastructure for enterprise and edge deployment scenarios.
Hashtag: #AIInfrastructure #AIInference #EdgeAI #EnterpriseAI #Singapore
https://www.marslabai.com/
https://www.linkedin.com/company/marslab-ai/
The issuer is solely responsible for the content of this announcement.
About MarsLab Pte Ltd
MarsLab Pte Ltd is a Singapore-based AI inference infrastructure company focused on enterprise and edge AI deployment scenarios. The company works across hardware systems, software stack integration, workload validation, and deployment economics, with a system-first approach to practical AI infrastructure.
Under the agreement, ACx and ALMI will share methodologies and best practices in mall asset operations, leasing strategy and project development to improve operational efficiency, enhance customer experience and maximize the long-term value of CP AXTRA’s land and assets, initially focusing on seven key stores of Makro. The parties will also explore future investment opportunities related to mall and asset development in Thailand, alongside collaborative initiatives for the development of new sites and the redevelopment of existing CP AXTRA sites across the country. This is the third agreement signed between CP AXTRA and Ayala, underscoring the strong partnership and continued collaboration between the two groups, following their previous agreements to operate Makro in the Philippines and expand regional business opportunities.
“This agreement with Ayala allows us to combine CP AXTRA’s deep understanding of the Thai retail market with Ayala’s decades of experience in developing and leasing shopping mall spaces. By applying proven methodologies to our Makro mall, we aim to elevate the standards of the retail environment we offer, not only improving the experience for our shoppers and tenants, but also fostering sustainable growth and creating long-term value for our asset and the surrounding community,” said Tanit Chearavanont, Group Chief Wholesale Business Officer, CP AXTRA Public Company Limited.”
“This is another milestone in our growing relationship and collaboration with the CP Group. Through this partnership, we intend to leverage the complementary strengths of two leading conglomerates to create world-class retail and real estate developments across markets. This also marks Ayala’s entry into the Thailand market, giving us a strong opportunity not only to share our expertise, but also to gain valuable insights from one of Southeast Asia’s most dynamic and developed retail markets. More broadly, this partnership aligns with Ayala’s strategy of bringing the best of the world to the Philippines while showcasing the best of the Philippines to the world,” said Mark Uy, Managing Director and Group Head of Strategy and Business Development, Ayala Corporation.
“Makro’s nationwide footprint gives it a meaningful role in the everyday lives of Thai consumers. Our opportunity is to help turn that everyday relevance into places people choose to stay, explore, and return to. By combining CP AXTRA’s market knowledge with Ayala Malls’ experience in curating retail partners, improving customer journeys, and building community-oriented retail destinations, we believe these sites can become stronger platforms for shoppers, merchant partners, and long-term asset growth,” said Mariana Zobel de Ayala, Managing Director and Group Head of Leasing and Hospitality of Ayala Land.
The collaboration brings two complementary strengths together. CP AXTRA is one of ASEAN’s leading wholesale and retail operators, with more than 2,700 Makro and Lotus’s stores. The company is a regional leader in multi-format, omnichannel retail platforms across Southeast Asia and is advancing toward retail-tech company. ALMI, is one of the Philippines’ leading mall operators, managing 34 shopping centers recognized for their strong retail planning, curated tenant mix, and enhanced customer experience across Southeast Asia. With extensive expertise in leasing, mall operations, facility management, and mixed-use development, ALMI is well positioned to support CP AXTRA in maximizing the value and potential of its Makro mall assets in Thailand. Ayala Corporation also brings a broader consumer and enterprise ecosystem that can complement CP AXTRA’s regional retail expansion, while ACx, its consumer retail unit, adds perspective on evolving customer behavior, format innovation, and retail partnerships.
The MoC builds on the two groups’ existing strategic partnership, which began in 2025 with the formation of CP AXTRA AC CORPORATION to operate Makro stores in the Philippines and was expanded to include a wider range of collaborative opportunities. This new agreement deepens that partnership further, marking the first time Ayala will bring its mall development and leasing expertise directly to CP AXTRA’s operations in Thailand.
Hashtag: #CPAXTRA
The issuer is solely responsible for the content of this announcement.
About CP AXTRA
CP AXTRA Public Company Limited, is an operator of Asia’s leading wholesaler and retailer, Makro and Lotus’s. The Company is based in Thailand, with operation across 10 countries. CP AXTRA is committed to fulfilling people’s lives with good health, love, joy, and well-being, by providing solutions and meeting customers’ daily needs with technology, innovation, and operational excellence. With over 30 years of retail experience, CP AXTRA is a trusted partner for both B2B and B2C customers, offering a comprehensive range of products and services. Today, it manages over 2,700 offline stores in Thailand and Asia, with strong online presence.
About Ayala Corporation
For more than 190 years, Ayala Corporation has been building businesses that enable people to thrive.
Ayala, currently one of the largest conglomerates in the Philippines, has meaningful presence in real estate, banking, digital services and telecommunications, and renewable energy. It likewise has a growing presence in healthcare, mobility, and logistics as well as investments in industrial technologies, education, and other ventures. Ayala manages its corporate social responsibility initiatives through Ayala Foundation.
About Ayala Malls
Ayala Malls is the premier lifestyle mall network in the Philippines, known for creating vibrant, well-curated destinations that bring together shopping, dining, culture, and community experiences. With 34 malls nationwide, Ayala Malls continues to lead in elevating the Filipino retail experience by offering a diverse mix of global and local brands, innovative spaces, and enriching events that celebrate local creativity and inclusivity. As part of Ayala Land, the country’s leading real estate developer, Ayala Malls is committed to building dynamic, sustainable spaces where people can connect, thrive, and enjoy life’s everyday moments.
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Aon Brings Leadership Forum to Manila to Help Organisations Navigate Risks and Drive Growth
The event is expected to convene more than 70 C-suite and senior business leaders from top organisations across the Philippines for a closed-door exchange on managing economic, workforce, climate and operational pressures. By bringing together diverse perspectives, the forum aims to foster practical insights and strategies that help organisations navigate uncertainty, protect their businesses and drive sustainable growth.
The program will be officially opened by Karl Hamann, CEO of Philippines for Aon, followed by a keynote from Andrew Jeffries, country director for the Asian Development Bank on the macroeconomic and geopolitical trends shaping the business environment.
Notable speakers include Terence Williams, head of Commercial Risk in Asia Pacific for Aon, and other firm executives alongside external regional leaders, including Annacel Natividad, chief risk officer and sustainability head for Aboitiz Foods Group, and Raymond Martin Aguilar, vice president and head of risk and property management for Globe Telecom, Inc.
“This forum reflects a fundamental shift in how organisations are evolving their approach to risk,” said Williams. “Across Asia Pacific, we are seeing a growing focus on using data and analytics to understand trade-offs, test scenarios and act with greater confidence. Bringing leaders together to share practical experience is critical to strengthening resilience while continuing to drive growth.”
A central feature of the forum will be a C-suite panel on adaptive leadership in a digital world, where senior leaders will share how they are balancing risk, resilience and growth, and the decisions shaping their organisations today. The session will be moderated by Irma Gaviola, head of Commercial Risk, Philippines for Aon.
The program will include risk masterclasses focused on key enterprise exposures, including cyber and climate risks, exploring how organisations can quantify risk, strengthen resilience and design more effective risk transfer strategies.
Participants will also be introduced to Aon’s Risk Analyzers, an interactive environment where clients can experience a suite of analytics-led tools that support scenario testing and supports better risk capital decisions. The tools are designed to help organisations assess exposures and evaluate strategic choices in real time.
“The Philippines sits at the intersection of strong economic growth and increasing risk complexity, said Hamann. “This forum creates a space for candid dialogue and practical insights to help organisations navigate risk with greater clarity and confidence.”
The Better Decisions Leadership Forum is part of Aon’s ongoing commitment to helping organisations turn insight into action – enabling more informed decision-making to protect and grow their business.
Hashtag: #Aon
The issuer is solely responsible for the content of this announcement.
About Aon
Aon plc (NYSE: AON) exists to shape decisions for the better — to protect and enrich the lives of people around the world. Through actionable analytic insight, globally integrated Risk Capital and Human Capital expertise, and locally relevant solutions, our colleagues provide clients in over 120 countries with the clarity and confidence to make better risk and people decisions that help protect and grow their businesses.
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Disclaimer
The information contained in this document is solely for information purposes, for general guidance only and is not intended to address the circumstances of any particular individual or entity. Although Aon endeavours to provide accurate and timely information and uses sources that it considers reliable, the firm does not warrant, represent or guarantee the accuracy, adequacy, completeness or fitness for any purpose of any content of this document and can accept no liability for any loss incurred in any way by any person who may rely on it. There can be no guarantee that the information contained in this document will remain accurate as on the date it is received or that it will continue to be accurate in the future. No individual or entity should make decisions or act based solely on the information contained herein without appropriate professional advice and targeted research.
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