Media OutReach
Li Ka Shing Foundation and Temasek Trust Jointly Commit S$12 Million to Acquire Systems and Advance Clinical Trial for Innovative Histotripsy Cancer Therapy in Singapore
- Li Ka Shing Foundation (LKSF) and Temasek Trust (TT) are purchasing and donating two Histotripsy Systems to the National Cancer Centre Singapore (NCCS) and the National University Cancer Institute, Singapore (NCIS) in Singapore to perform clinical trials to study novel ultrasound therapy for liver, kidney and pancreatic cancers.
- The funding from LKSF and TT will be disbursed through a Donor-Advised Fund managed by TT Foundation Advisors (TTFA), which catalyses additional capital from other donors to support cancer research.
SINGAPORE – Media OutReach Newswire – 04 April 2025 – The Li Ka Shing Foundation (LKSF) and Temasek Trust (TT) have committed S$12 million to bring innovative non-invasive ultrasound-based histotripsy tumour clinical trials to Singapore.
The National Cancer Centre Singapore (NCCS) and the National University Cancer Institute, Singapore (NCIS) will each receive one Histotripsy System – the first of such to be available in Southeast Asia. The funding from LKSF and TT will also support a clinical trial in Singapore for patients with liver, kidney, and pancreatic cancers, advancing regional cancer research and innovation.
Mr. Dickson Lim, Head, TTFA, said, “We at TTFA are delighted to have the Li Ka Shing Foundation and Temasek Trust come together to catalyse this important initiative, to study this innovative non-invasive ultrasound-based cancer therapy in Southeast Asia. We are privileged to work alongside NCCS and NCIS to support clinical research and trials to use this novel modality that targets important cancers. Over time, we aim to attract additional philanthropic capital from other donors to sustainably support the next phase of cancer research.”
Rising Regional Cancer Burden and the Need for Innovative Treatment
Liver, kidney, and pancreatic cancers are on the rise across Asia, with Southeast Asia experiencing the fastest-growing incidence and mortality rates. Factors such as aging populations, changing lifestyles, and environmental exposure contribute to the regional cancer burden. In Singapore, liver cancer is the third most common cause of cancer death for men, with liver and pancreatic cancers among the top 10 causes of cancer mortality. These cancers often do not show symptoms until the later stages, making early detection and effective treatment difficult.
Histotripsy: An Innovative Technology
Developed by US medical company, HistoSonics, the HistoSonics Histotripsy System generates microbubbles that rapidly expand and collapse, producing shock waves that break down tumours at the cellular level. This approach does not require surgery, and can non-invasively destroy tumours, including those that cannot be surgically removed.
Unlike surgery, radiotherapy, or traditional ablation, histotripsy requires no incisions or radiation, offering a painless, scarless, and bloodless treatment.
Clinical Trial on Histotripsy Therapy and Research in Asia
The application for the clinical trial using the HistoSonics Histotripsy System is being prepared. Professor Brian Goh Kim Poh, Head of Hepatopancreatobiliary and Transplant Surgery, NCCS and Singapore General Hospital, and principal investigator of the trial, will work alongside a team of oncologists, interventional radiologists and researchers from both NCCS and NCIS.
Professor Goh said, “We are excited to have the opportunity to embark on clinical trials for liver, kidney and pancreatic cancers which are prevalent in Southeast Asia. We plan to initiate trials for liver cancers first. While surgery and local ablative therapies are the main treatment modalities for liver cancers today, not all patients are suited to undergo these invasive treatments due to various factors such as patient fitness, tumour location or underlying liver disease. For these patients, innovations such as histotripsy offer an alternative option with potential advantages as it is non-invasive. We are extremely grateful to the Li Ka Shing Foundation and Temasek Trust for their generosity and strong support towards advancing cancer research by enabling us to study this novel technology.”
Associate Professor Glenn Kunnath Bonney, Senior Consultant, Division of Surgical Oncology, NCIS, said: “We are currently preparing for the clinical trial of histotripsy as a potential treatment approach for patients with liver and other complex cancers. I have just returned from an international meeting where I was shown the promising results from early clinical trials. This initiative reflects our ongoing commitment to expanding evidence-based options through rigorous research, with the goal of improving patient outcomes over time. We are grateful to the Li Ka Shing Foundation and Temasek Trust for their support, and look forward to working with our partners to build the necessary foundation for careful clinical studies.”
The clinical trial is slated to commence later this year, with a targeted enrolment of 40 patients who meet the trial criteria and are reviewed by a multi-disciplinary team.
Ensuring Sustainable Impact through Strategic Philanthropy
To drive long-term impact in the region, the funding from LKSF and TT will be disbursed through a Donor-Advised Fund (DAF) managed by TTFA, the philanthropy advisory services arm of TT. Through the DAF, TTFA aims to attract additional capital from other donors over time to sustainably support the next phase of cancer research.
Hashtag: #LiKaShingFoundation #TemasekTrust
The issuer is solely responsible for the content of this announcement.
About Li Ka Shing Foundation
Li Ka Shing Foundation believes in philanthropy with societal impact. Since 1980, we have been helping to reform education and further medical research. To date, Mr Li Ka-shing has invested over HK$30 billion in projects covering education, medical services, charity and anti-poverty programmes, with about 80% of the projects in Mainland China and Hong Kong.
About Temasek Trust
Temasek Trust was established by Temasek Holdings and is a steward of philanthropic assets. It aims to catalyse positive impact by protecting the planet, uplifting communities, connecting people, and advancing capabilities. By forging new pathways for philanthropy and impact investing with like-minded partners, Temasek Trust seeks to promote catalytic philanthropy as a force for good. For more information, visit www.temasektrust.org.sg. Follow us on http://www.nccs.com.sg/
About National University Cancer Institute, Singapore (NCIS)
The National University Cancer Institute, Singapore (NCIS) is an academic, national specialist centre for cancer under the National University Health System (NUHS), and is the only public cancer centre in Singapore that treats both paediatric and adult cancers in one facility.
As one of two national cancer centres in Singapore, NCIS (pronounced as “n-sis”) offers a broad spectrum of cancer care and management from screening, diagnosis and treatment to rehabilitation and survivorship, as well as palliative and long-term care. NCIS’ strength lies in the multidisciplinary approach taken by our clinician scientists and clinician-investigators to develop a comprehensive and personalised plan for each cancer patient.
NCIS provides the full suite of specialised oncology and haematology services at the NUH Medical Centre at Kent Ridge, Singapore, including those by the NCIS Chemotherapy Centre, NCIS Radiotherapy Centre and NCIS Cellular Therapy Centre.
NCIS also offers cancer services at other hospitals in Singapore:
* NCIS Cancer & Blood Clinic @ Ng Teng Fong General Hospital
* NCIS Radiotherapy Centre @ Tan Tock Seng Hospital
* NCIS Radiotherapy Clinic @ Khoo Teck Puat Hospital
To bring cancer care even closer to our patients, our NCIS on the Go programme delivers a range of cancer services at clinics within the community for their convenience. For more information, please visit www.ncis.com.sg.
About HistoSonics
HistoSonics is a privately held medical device company developing non-invasive platforms and proprietary sonic beam therapy utilizing the science of histotripsy, a novel mechanism of action that uses focused ultrasound to mechanically destroy and liquify unwanted tissue and tumours. The company is currently focused on commercialising their HistoSonics Histotripsy System in the US and select global markets for liver treatment while expanding histotripsy applications into other organs like kidney, pancreas, prostate, brain, and others. HistoSonics has offices in Ann Arbor, Michigan, and Minneapolis, Minnesota.
For more information on the HistoSonics Histotripsy System, please visit: www.histosonics.com/. For patient related information, please visit: www.myhistotripsy.com/.
Media OutReach
Woodfibre LNG Marks 2025 as a Year of Construction Progress, Environmental Stewardship and Community Partnership
Over the past year, the project advanced from planning into visible, on-the-ground execution. Major construction milestones included the pouring of foundations for key modules, continued progress on marine piling, and further implementation of modular construction techniques designed to reduce on-site footprint while accelerating delivery timelines.
These advancements were achieved through close collaboration with project partners, suppliers and contractors, and in partnership with the Sḵwx̱wú7mesh Úxwumixw (Squamish Nation).
In 2025, Woodfibre LNG, a member of the RGE group of companies founded by Sukanto Tanoto, continued to operate its floatel workforce accommodation solution, designed to minimise pressure on local housing and community services. As of November, two floatels were in active operation, providing high-quality, safe and comfortable living conditions for the project workforce while supporting construction efficiency.
Environmental protection remained a central focus throughout the year. The project’s Marine Mammal Monitoring Programme, which includes hydroacoustic monitoring, exclusion zones and shore-based observation posts, delivered measurable outcomes by enabling real-time operational decisions, including pauses to marine activities when marine mammals entered exclusion areas.
In parallel, remediation of legacy materials from the former pulp mill site continued, with hundreds of thousands of tonnes of historical waste removed. These efforts have contributed to improving site conditions for both local communities and marine and terrestrial ecosystems in Howe Sound.
Woodfibre LNG’s Operator Training Programme, delivered in partnership with the Squamish Nation Training and Trades Centre and the British Columbia Institute of Technology (BCIT), progressed throughout the year. The programme’s first cohort of graduates transitioned into full-time roles, supporting the development of long-term, skilled local employment opportunities linked to the project.
Through its Community Partnership Programme (CPP), Woodfibre LNG continued to invest in local communities across the Sea-to-Sky corridor. In 2025, the programme surpassed $1 million in total grants since its inception, supporting initiatives in sports, healthcare, emergency services, arts and culture, and youth development.
Luke Schauerte, CEO of Woodfibre LNG, said, “2025 has been a year of significant progress for Woodfibre LNG. We are proud of what our team and partners have accomplished together and look forward to building on this momentum in the year ahead.”
With more than half of the project’s development now complete, Woodfibre LNG remains focused on advancing construction safely and responsibly, while maintaining strong partnerships with Indigenous communities, local stakeholders and regulators.
As the project looks ahead to 2026, Woodfibre LNG continues its work toward delivering lower-carbon, responsibly produced Canadian energy to international markets.
Hashtag: #RGE #PacificEnergy #PacificCanbriamEnergy #WoodfibreLNG #LNG #environment #partnerships #LNG #liquefiednaturalgas #energy #sustainability
The issuer is solely responsible for the content of this announcement.
About Woodfibre LNG
The Woodfibre LNG Project is owned by Woodfibre LNG Limited Partnership, owned 70 per cent by Pacific Energy Corporation (Canada) Limited and 30 per cent by Enbridge Inc. The Woodfibre LNG facility is being built on the site of the former Woodfibre pulp mill site, which is located about seven kilometres southwest of Squamish, B.C. Woodfibre LNG will source its natural gas from Pacific Canbriam Energy, a Canadian company with operations in Northeastern British Columbia. Pacific Canbriam is an industry leader in sustainable natural gas production. Woodfibre LNG and Pacific Canbriam Energy are subsidiaries of Pacific Energy Corporation Limited. Woodfibre LNG is the first industrial project in Canada to recognise a non-treaty Indigenous government, Sḵwx̱wú7mesh Úxwumixw (Squamish Nation), as a full environmental regulator.
Media OutReach
New Opportunities in Southeast Asia’s Digital Shift: Thailand Emerges as the New ASEAN’s AI Hub
The expansion of AI and data centers (DCs) in Thailand is driving several transformative trends:
- Changing data traffic patterns. As DCs multiply in Bangkok, Chonburi, and beyond, Thailand is evolving from a traditional data “transit point” into a regional “convergence hub.” East-west digital traffic is accelerating, with Thai DC clusters increasingly meeting the computing demands of Southeast Asia and the broader Asia-Pacific.
- Optimized data routing. Data flows that once relied on submarine cables via Hong Kong and Singapore are gradually shifting to land-based digital corridors linking China, Laos, and Thailand. This route reduces data transmission latency from southwestern China to Southeast Asia.
- Elevated business expectations. Demand is shifting beyond “sufficient bandwidth” toward “high-quality experience.” Thailand sits in a “latency sweet spot” for key Asia-Pacific markets, with latencies to Singapore, Vietnam, and Malaysia falling within an optimal range—a crucial advantage for latency-sensitive sectors like autonomous driving, telemedicine, and fintech.
New opportunities inevitably bring new challenges, and Thailand also addresses the following three challenges:
1. Massive traffic impacting existing networks: Compared with mature hubs like Singapore, Thailand has insufficient international submarine cables. A large volume of cross-border data still needs to be transmitted through detours. Meanwhile, as DC investments continue to accelerate, traffic will keep rising. Analysis shows that by 2029, Thailand’s DC capacity may reach 2000 MW, with cross-region traffic surging to 630 Tbps. The current network architecture is no longer capable of supporting such heavy traffic.
2. Latency advantages not fully realized: Despite its geographic advantages, Thailand’s network latency performance has yet to reach its full potential. Routes to key markets, like China, still require third-party transit. What’s more, traditional network scheduling lacks intelligent route selection capabilities, making it difficult to provide deterministic assurance for latency-sensitive services like financial transactions and real-time AI interactions.
3. Potential risks in network reliability: Thailand’s network reliability faces structural challenges. Single points of failure have previously caused hours-long interruptions to critical services, directly undermining enterprise users’ confidence.
To overcome these challenges, Thailand can take a systematic approach to upgrading its digital infrastructure, aiming to build next-generation AI-ready networks.
1. Building ultra-high-bandwidth “sea-land” connectivity. By actively introducing new submarine cables, Thailand can significantly enhance its connectivity with the Asia-Pacific region and the world. Meanwhile, accelerating the construction and expansion of key terrestrial cable routes—such as China-Laos-Thailand and Thailand-Malaysia-Singapore—will transform Thailand’s geographic advantage into a tangible connectivity advantage.
2. Optimizing network routes to create a regional low-latency core. Strengthening the Kunming-Laos-Thailand terrestrial cable route will continuously reduce transmission latency between China and Thailand, meeting the needs of real-time applications. In addition, the introduction of autonomous networks will enable automatic selection of the optimal, shortest route, shifting from “best effort” to “deterministic low latency.”
3. Designing a “never-interrupted” high-resilience architecture. Deploying active-active DC networks with millisecond-level switchover capabilities ensures the continuity of core services. Meanwhile, AI-driven intelligent O&M can reduce fault detection and diagnosis from hours to minutes.
Thailand’s booming AI and DC industries are driving rapid growth in regional and cross-border business demand. In this trend, network infrastructure construction centered on DCs is the core engine that drives AI transformation, propelling Thailand toward its vision of becoming the new AI hub for ASEAN.
Hashtag: #huawei
The issuer is solely responsible for the content of this announcement.
Media OutReach
MyRepublic Launches Card Sub, Singapore’s First Subscription Service for Trading Card Game Fans
Hashtag: #CardSub, #MyRepublic #MyRepublicCardSub #CardSubSG #TCG #GeeksUseUs
https://myrepublic.net/sg/
https://www.linkedin.com/company/myrepublic
https://x.com/myrepublic
https://www.facebook.com/MyRepublicSG/
https://www.instagram.com/myrepublicsg/
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MyRepublic
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