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SMART launches new research group WISDOM to pioneer technologies that will help machines “see” like humans
- Multi-million-dollar, three-and-a-half-year programme to advance Singapore’s optoelectronics and photonics capabilities and semiconductor industry, which generated over S$133 billion in 2023 and accounts for approximately 7% of Singapore’s GDP
- Bringing together over 20 Singapore and US-based researchers, this is the first time a programme will study the combination of three integral components: optics, optoelectronics and electronics
- WISDOM supports Singapore’s Future of Microelectronics (FME) national initiative, and has key partnerships with leading research institutions including the National Semiconductor Translation and Innovation Centre (NSTIC)
- The IRG’s research endeavours are expected to benefit industries such as automotive, consumer electronics, healthcare, and space travel and sample collection – including applications in autonomous driving, augmented reality, robotics and high-speed data communication
SINGAPORE – Media OutReach Newswire – 7 May 2025 – Imagine creating 3D-sensing technologies so lightweight, compact and high-performance that they could take us to planets beyond Mars. The Singapore-MIT Alliance for Research and Technology (SMART), Massachusetts Institute of Technology’s (MIT) research enterprise in Singapore, has launched a new interdisciplinary research group (IRG) focused on developing next-generation 3D-sensing technologies for practical use across industries such as automotive, consumer electronics, aerospace and healthcare, among others.
Jointly led by faculty from MIT and Nanyang Technological University, Singapore (NTU Singapore), the Wafer-scale Integrated Sensing Devices based on Optoelectronic Metasurfaces (WISDOM) IRG will focus on developing ultra-thin, scalable sensing devices – systems that allow machines such as autonomous vehicles and robots to perceive depth, shape and spatial detail safely and with more versatility, much like human vision.
3-Dimensional (3D) sensing is essential for many modern applications, from autonomous vehicles and robotics to augmented reality and medical diagnostics. However, current systems still fall short of human-like perception capabilities, which pose limitations such as contextual unawareness and decision errors.
Today’s optical systems are also often bulky, expensive and difficult to mass-produce due to reliance on complex components and manual assembly. While new materials called optoelectronic metasurfaces — which are ultra-thin and can control light in powerful new ways — show great potential, it has been difficult so far to turn them into practical, widely used products, due to challenges in how these materials are combined with other technologies and manufactured at large scale.
SMART WISDOM will be helmed by Co-Lead Principal Investigators Prof Juejun Hu, Professor of Materials Science and Engineering at MIT, and Prof Tan Chuan-Seng, Professor of Electronic Engineering at the School of Electrical and Electronic Engineering at NTU Singapore.
“What makes me really excited about WISDOM is that we’re putting together pieces that haven’t been combined before – to benefit a ton of industries and use cases. For example, think how a super light and powerful LiDAR system could make trips to planets beyond Mars a reality. It’s like having a whole new set of eyes for exploration, and about making the seemingly impossible, possible,” said Prof Juejun Hu, Co-Lead Principal Investigator, WISDOM.
Combining expertise from five leading institutions
SMART brings together top researchers from leading institutions in the United States and Singapore, including MIT, NTU Singapore, National University of Singapore (NUS), Stanford University and University of Illinois Urbana-Champaign (UIUC), to redefine how optical metasurfaces are designed, integrated and manufactured.
This multi-million, multi-year effort, supported by the National Research Foundation (NRF) Singapore under its Campus for Research Excellence and Technological Enterprise (CREATE) programme, brings together leading experts across disciplines in photonics, materials science and semiconductor engineering to position Singapore at the forefront of global innovation in sensing technologies and advanced manufacturing.
World-first approach to pioneering 3D-sensing and next-generation applications
WISDOM will capitalise on wafer-scale integration using standard silicon complementary metal-oxide-semiconductor (CMOS) processes to revolutionise how meta-optical systems are produced. This is the first time a programme is put together to study the combination of these three separate elements: optical metasurfaces, optoelectronic devices with a focus on light-emitting diodes (LEDs) and vertical surface emitting laser arrays (VCSELs); and silicon CMOS electronics.
At the heart of WISDOM’s pioneering research is their world-first approach that integrates the three elements into a wafer-scale platform. This tri-element integration seeks to unlock entirely new functionalities in optical metasurface technology, enabling next-generation sensing systems with multi-modal illumination and detection, advanced displays with built-in high-speed communication, and biomedical devices with versatile light sources for diagnostics and therapeutics.
“The launch of WISDOM marks an exciting chapter in SMART’s and MIT’s long legacy in Singapore – bringing together the best in their fields from US, Singapore and the region for interdisciplinary research and collaboration to drive world-class research and innovation with commercial and societal impact for Singapore and beyond. The first-of-its-kind research will pioneer groundbreaking advancements for next-generation sensing systems, enabling transformative solutions across industries such as automotive, healthcare, aerospace and consumer electronics,” said Bruce Tidor, Chief Executive Officer and Director (Interim), SMART.
WISDOM’s inaugural project aims to develop a high-performance, metasurface-enabled LiDAR prototype, addressing key challenges in scalability, integration and performance. By combining metasurface optics, optoelectronic devices, and CMOS electronics on a single silicon substrate, WISDOM seeks to redefine the capabilities of LiDAR systems. This innovation promises to enhance detection accuracy, extend range and field-of-view, and reduce motion artifacts, with transformative implications for industries such as automotive, healthcare, robotics and unmanned aerial vehicles (UAVs). Beyond improving safety in autonomous vehicles and navigation in drones, it also opens doors to revolutionary applications like glasses-free 3D displays and high-speed optical communication, laying the groundwork for smarter, more efficient technologies that will shape the future.
“WISDOM represents a paradigm shift in how meta-optical systems are integrated – from discrete assembly to wafer-scale packaging. Even at the research stage, we have a clear objective to bring our innovations to market and societal impact – enabling transformative sensing technologies for mass-market applications. WISDOM is designed to streamline manufacturing by eliminating costly and intricate die-to-die assembly, significantly improving throughput,” said MIT Prof Hu Juejun.
“By combining NTU’s two decades of expertise in electronics engineering and wafer packaging with MIT’s strengths in optical systems, we aim to create a new platform for large-scale manufacturing of optical metasurfaces using industry-standard CMOS processes. NTU is known for translating fundamental research into real-world technologies, and this collaboration builds on that strength. Ranked top in the world for Electrical and Electronic Engineering1, we are well-placed to deliver innovations that are both scalable and commercially viable, while also training the next generation of engineers to lead in areas like Augmented Reality, robotics and consumer technology,” said NTU Prof Tan Chuan-Seng.
As MIT’s research enterprise in Singapore, SMART is dedicated to driving innovation that powers future industries and transforms global technological landscapes. WISDOM adds on to SMART’s continuing commitment to advancing cutting-edge and translational research in fields such as artificial intelligence, agriculture, antimicrobial resistance, cell therapy and more. In addition to advancing scientific understanding, the IRG’s work is expected to contribute to intellectual property development, technology licensing, and the creation of Singapore research spin-offs and startups in related industries.
Hashtag: #SMART
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About Wafer-scale Integrated Sensing Devices based on Optoelectronic Metasurfaces (WISDOM)
WISDOM is an interdisciplinary research group (IRG) launched in April 2025 by SMART, MIT’s research enterprise in Singapore. WISDOM is the first research and industry endeavour to study and integrate optical metasurfaces, light emitting diodes (LEDs) and vertical surface emitting laser arrays (VCSELs), and complementary metal-oxide semiconductor (CMOS) electronics for industry and commercial application. By developing innovative 3D-sensing technologies that enhance system performance, scalability and cost efficiency, WISDOM aims to revolutionise optoelectronics and photonics, and address key challenges in semiconductor manufacturing and other key industries. These 3D-sensing technologies will deliver impactful advancements that drive progress in sensor innovation while fostering opportunities for commercial applications and societal benefits in Singapore and globally.
About Singapore-MIT Alliance for Research and Technology (SMART) [新加坡-麻省理工学院科研中心]
Singapore-MIT Alliance for Research and Technology (
SMART) is MIT’s Research Enterprise in Singapore, established by the Massachusetts Institute of Technology (MIT) in partnership with the National Research Foundation of Singapore (NRF) since 2007. SMART is the first entity in the Campus for Research Excellence and Technological Enterprise (CREATE) developed by NRF. SMART serves as an intellectual and innovation hub for research interactions between MIT and Singapore. Cutting-edge research projects in areas of interest to both Singapore and MIT are undertaken at SMART. SMART currently comprises an Innovation Centre and five Interdisciplinary Research Groups (IRGs): Antimicrobial Resistance (AMR), Critical Analytics for Manufacturing Personalized-Medicine (CAMP), Disruptive & Sustainable Technologies for Agricultural Precision (DiSTAP), Mens, Manus and Machina (M3S), and Wafer-scale Integrated Sensing Devices based on Optoelectronic Metasurfaces (WISDOM).
SMART research is funded by the National Research Foundation Singapore under the CREATE programme.
For more information, please visit http://smart.mit.edu
Media OutReach
St. George’s University Prepares Future South Korean Physicians for the Growing Global Cancer Care Challenge
Recognizing the importance of addressing workforce shortage in South Korea, St. George’s University (SGU) School of Medicine in Grenada, West Indies, highlights how its medical education approach supports the development of clinical competencies relevant to cancer care across healthcare settings.
These challenges reflect broader global trends, where cancer care increasingly depends on multidisciplinary teams rather than specialty expansion alone. SGU’s curriculum is designed to build a strong foundation in clinical diagnosis, patient communication and multidisciplinary care, which are essential skills for effective oncology and cancer-related care. Through anatomy labs, simulation-based learning, and integrated digital tools, students develop foundational clinical skills in structured, supervised environments designed to reflect real-world medical practice.
The curriculum also integrates traditional cadaveric dissection with modern 3D anatomical modeling. This blend helps students visualize the human body in a holistic way while reinforcing knowledge through their hands-on interaction. SGU’s simulation lab also enables medical students to have their first direct interaction with ill patients in a safe, simulated learning environment.
On top of core medical training, SGU offers early exposure to prevention, diagnosis and patient-centered care to prepare graduates to tackle complex health issues. SGU has developed long-standing relationships with more than 75 established hospitals and clinical centers in the US and UK. These clinical placements provide exposure to diverse patient populations and care environments, including settings where cancer diagnosis and management are part of routine clinical practice.
South Korean SGU alumni are contributing to healthcare systems through roles that intersect with cancer diagnosis, treatment coordination, and long-term patient care. For example, Dr. Julia Hweyryoung Cho, MD 2022 is practicing internal medicine, which plays a crucial role in cancer care. Internal medicine physicians are often involved in the initial diagnosis of cancer, managing complex medical conditions that may arise during treatment and providing long-term comprehensive care and survivorship planning for patients with a history of cancer.
In observance of World Cancer Day 2026, SGU encourages all medical professionals and organizations to collaboratively address global cancer care challenges. This includes recognizing and meeting the cancer healthcare needs of individuals and communities in South Korea.
For more information on the programs and tracks available through SGU School of Medicine, visit SGU’s website.Hashtag: #St.George’sUniversity
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Finalists and Semifinalists for $1 Million Seeding The Future Global Food System Challenge Announced
Created and funded by Seeding The Future Foundation and, for the first time, hosted by Welthungerhilfe (WHH), the Challenge attracted a record 1,600+ applications from innovator teams in 112 countries, underscoring growing global momentum for food systems transformation.
Following a multi-stage, rigorous international review process, 36 teams have advanced across three award levels. These include 16 Seed Grant Finalists (competing for 8 awards of USD 25,000), 12 Growth Grant Semifinalists (competing for 3 awards of USD 100,000), and 8 Seeding The Future Grand Prize Semifinalists (competing for 2 awards of USD 250,000).
“Hosting the GFSC reflects Welthungerhilfe’s commitment to accelerating bold, scalable innovations where they are needed most. This year’s diversity of solutions underscores the complexity of food system challenges and the creativity of innovators worldwide.” said Jan Kever, Head of Innovation at Welthungerhilfe
The submitted innovations span diverse themes and approaches, including climate-smart production, nutrient-dense foods, food loss reduction, and inclusive market models, reflecting the complexity and interconnected nature of today’s food systems challenges.
“The Seeding The Future Global Food System Challenge exists to catalyze impactful, bold, and scalable innovations that advance food systems transformation. We are excited to work alongside Welthungerhilfe as a trusted partner and host of the Challenge and are encouraged by the quality and diversity of innovations emerging from this first year of collaboration.” said Bernhard van Lengerich, Founder and CEO of Seeding The Future Foundation
While the number of awards is limited, all semifinalists and finalist applicants plus all applicants with any prior recognition of other innovation competitions can join the STF Global Food System Innovation Database and Network—currently in beta testing with the Food and Agriculture Organization of the United Nations—vastly expanding their visibility and reach across a global audience.
List of 2025 GFSC Seed Grant Finalists, Growth Grant and Seeding The Future Grand Prize Semifinalists
Find details here: welthungerhilfe.org/gfsc-finalists
Seeding The Future Grand Prize Semi-Finalists
- CNF Global, Kenya
- ZTN Technology PLC, Ethiopia
- One Acre Fund, Rwanda
- Sanku, Tanzania
- Nabahya Food Institute (NFI), Democratic Republic of the Congo
- ABALOBI, South Africa
- metaBIX Biotech, Uruguay
- Nurture Posterity International, Uganda
Growth Grant Semi-Finalists
- Baobaby, Togo
- Safi International Technologies Inc., Canada
- Centro Internacional de Mejoramiento de Maíz y Trigo (CIMMYT), Mexico
- Farmlab Yeranda Agrisolution Producer Company Limited, India
- Banco de Alimentos Santa Fe (BASFE), Argentina
- Chartered Consilorum (Pty) Ltd, South Africa
- American University of Beirut, Environment and Sustainable Development Unit (ESDU at AUB), Lebanon
- The Source Plus, Kenya
- Iviani Farm Limited, Kenya
- Rwandese Endogenous Development Association, Rwanda
- NatureLEAD, Madagascar
- Ndaloh Heritage Organisation, Kenya
Seed Grant Finalists
- Inua Damsite CBO, Kenya
- World Neighbors, United States
- Keloks Technologies Ltd, Nigeria
- REBUS Albania, Albania
- Tanzania Conservation and Community Empowerment Initiative (TACCEI), Tanzania
- Intrasect, Switzerland
- VKS AGRITECH, India
- Murmushi People’s Development Foundation, Nigeria
- Levo International, Inc., United States
- Effective Altruism Research Services Ltd, Uganda
- Taita Taveta University, Kenya
- CultivaHub, Democratic Republic of the Congo
- Resource Hub for Development (RHD), Kenya
- FUTURALGA S.COOP.AND, Spain
- West Africa Centre for Crop Improvement, University of Ghana, Ghana
- Sustainable Solutions Kenya, Kenya
Hashtag: #TheFutureGlobalFoodSystemChallenge
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About Seeding The Future Foundation
STF is a private nonprofit dedicated to ensuring equitable access to safe, nutritious, affordable, and trusted food. It supports innovations that transform food systems and benefit both people and planet. More at Seeding the future.
About Welthungerhilfe
WHH is one of Germany’s largest private aid organizations, striving for a world without hunger since 1962. More at: Welthungerhilfe (WHH)
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PolyU develops novel antibody targeting fat cell protein, offering new approach to treating metabolism-related liver cancer
Metabolic dysfunction-associated steatotic liver disease (MASLD), commonly known as fatty liver disease, currently affects around a quarter of the global population and is an important risk factor for liver cancer. In affected individuals, fat cells induce insulin resistance and chronic inflammation, leading to excessive fat accumulation in the liver. This ultimately impairs liver function and may progress to liver cancer. Treatment options for MASLD-induced liver cancer remain limited and the effectiveness of current immunotherapies is suboptimal.
A breakthrough study led by Prof. Terence LEE, Associate Head and Professor of the PolyU Department of Applied Biology and Chemical Technology, and his research team has revealed that an adipocyte-derived protein, known as fatty acid-binding protein 4 (FABP4) is a key driver that accelerates tumour growth. Through mass spectrometry, the team confirmed that patients with MASLD-induced liver cancer had markedly elevated FABP4 levels in their serum. Further investigations showed that FABP4 activates a series of pro-proliferative signalling pathways within cells, causing cancer cells to multiply and grow more rapidly.
Prof. Lee’s team has successfully developed a monoclonal antibody that neutralises FABP4. This antibody not only inhibits the growth and proliferation of FABP4-driven cancer stem cells, but also enhances the ability of immune cells to combat cancer.
Prof. Lee said, “This neutralising antibody against FABP4 demonstrates significant potential in inhibiting tumour growth and activating immune cells, providing a complementary approach to current immunotherapy strategies. Our findings highlight that targeting adipocyte-derived FABP4 holds promise for treating MASLD-induced liver cancer.”
Prof. Lee added that gaining deeper insights into how adipocyte-derived FABP4 affects liver cancer cells helps to explicate the disease mechanisms of liver cancer, particularly in obese individuals. Intervening in the relevant signalling pathways could provide effective methods to combat this aggressive malignancy.
Prof. Lee believes that, as this adipocyte-targeted immunotherapy continues to mature, it will bring more treatment options to MASLD patients. He remarked, “If its efficacy can be proven in clinical trials, it could offer new hope to many affected individuals.”
The research is supported by the Innovation and Technology Fund of the Innovation and Technology Commission of the Government of the Hong Kong Special Administrative Region of the People’s Republic of China. PolyU has filed a non-provisional patent for the developed antibody and is continuing to optimise its binding affinity to facilitate future clinical applications.
Hashtag: #PolyU #FattyLiver #Cancer #LiverCancer #理大 #香港理工大学 #肝癌 #癌症 #脂肪肝
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