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GSK Gets $170m to Produce World’s First Malaria Vaccine

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Mosquirix Malaria Vaccine

By Adedapo Adesanya

The pharmaceutical company, GSK, has been awarded a contract to produce the world’s first malaria vaccine so that millions more children will be protected against the killer disease.

This was announced by the UN Children’s Fund (UNICEF). The value of the deal is about $170 million and will lead to the production of 18 million doses of the RTS,S vaccine being available over the next three years, potentially saving thousands of young lives annually.

Malaria remains one of the biggest killers of children under five. In 2020, nearly half a million boys and girls died from the disease in Africa alone, a rate of one death every minute.

The Director of UNICEFOpens, Etleva Kadilli, stated that Opens in new window rollout sends a clear message to malaria vaccine developers to continue their work.

“We hope this is just the beginning. Continued innovation is needed to develop new and next-generation vaccines to increase available supply, and enable a healthier vaccine market,” she said.

“This is a giant step forward in our collective efforts to save children’s lives and reduce the burden of malaria as part of wider malaria prevention and control programmes”.

Malaria is caused by parasites and transmitted to humans through infected female Anopheles mosquitoes. While the disease is preventable and curable, it can be fatal if left untreated.

More than 30 countries have areas with moderate to high malaria transmission, according to data from the World Health Organization (WHOOpens in new window), and the vaccine could provide added protection to more than 25 million children each year once the supply ramps up.

The RTS,S malaria vaccine – the result of 35 years of research and development – is the first-ever vaccine against a parasitic disease.

Business Post had reported that the Pilot programme was launched in 2019, coordinated by WHO, in three countries – Ghana, Kenya and Malawi – and has reached more than 800,000 children.

Last October, the UN health agency recommended Opens in new windowits widespread use in countries with moderate to high malaria transmission.

That December, Gavi, the Vaccine Alliance, took the decision to provide funding for malaria vaccine programmes in eligible countries, thus opening the pathway for the broader roll-out of the vaccine.

Speaking on this, CEO Mr Seth Barkley reported that Gavi recently opened the “application window” for funding requests.

“Thanks to UNICEF’s procurement work, we now have more certainty on supply and can move a step further towards getting this life-saving vaccine to the people who need it the most. As manufacturing ramps up over time, we hope that increasing volumes will also lead to more sustainable, lower prices,” he said.

Meanwhile, WHO has welcomed progress in securing supply and timely access to the vaccine so that more countries can introduce it as soon as possible.

“Lives are at stake, every day,” said Dr Kate O’Brien, Director of WHO’s Department of Immunization, Vaccines and Biologicals, “Given the initial limited supply, it is crucial that children living in areas where the risk of disease and need is highest are prioritized first”.

UNICEF expects that demand for the malaria vaccine will be high among affected countries. As with any new vaccine, supply will be limited at first, the agency said but will increase as manufacturing capacity ramps up over time, which in turn will lead to a decrease in costs per dose.

Adedapo Adesanya is a journalist, polymath, and connoisseur of everything art. When he is not writing, he has his nose buried in one of the many books or articles he has bookmarked or simply listening to good music with a bottle of beer or wine. He supports the greatest club in the world, Manchester United F.C.

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Mums Feel Warmth Initiative Raises Postpartum Depression Awareness

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Mums Feel Warmth Postpartum Depression

By Modupe Gbadeyanka

A transformative webinar to raise awareness on postpartum depression (PPD) by nursing mothers has been organised by MSc Media and Communication students from the School of Media and Communications of the Pan-Atlantic University.

The programme titled Beyond Baby Blues: Understanding and Overcoming Postpartum Depression was held on January 7, 2025.

It was put together by the students under the Mums Feel Warmth initiative, with experts in the field invited to speak on the matter aimed at empowering mothers and fostering a sense of reassurance.

The webinar was to highlight the journey through postpartum depression, offering a message of hope, resilience, and the importance of mental health support for mothers everywhere.

One of the speakers, Dr Laja Odunuga, who is the Care Coordinator for AVON HMO, explained the difference between the common “baby blues” and the more severe, long-lasting PPD.

The discussion highlighted how PPD can manifest not just as sadness but through severe fatigue, disconnection from the newborn, and loss of interest in activities, which can last well beyond the typical two-week period associated with baby blues.

Another expert, Ms Otomfon Ibanga, the Assistant Lead Nurse for Q-Life Family Clinic, emphasised the role of support systems, urging families and friends to be vigilant for signs of PPD and to provide a nurturing environment.

She also discussed prevention strategies, including prenatal planning for support structures and post-delivery management through therapy or medication.

On his part, Dr Chimaraoke Obialo, who is the Medical Director of Life Amada Health Consultancy, addressed the stigma surrounding PPD, advocating for education to transform societal perceptions from judgement to support.

The webinar underscored the need for community involvement, not just in recognising symptoms but in actively participating in the healing process by offering emotional and practical support.

The Mums Feel Warmth webinar was more than just an educational session; it was a call to action for society to embrace and support new mothers dealing with PPD.

By fostering open conversations and providing platforms for sharing experiences, Mums Feel Warmth continues to lead the charge against the stigma of PPD.

The commitment shown by the panellists and attendees alike promises a future where every mother has access to the understanding and care needed to navigate through the complexities of postpartum depression, ensuring that the joy of motherhood is not overshadowed by mental health challenges.

Mums Feel Warmth, with its core values of empathy, compassion, hope, community, and education, speaks to the Sustainable Development Goal 3, advocating for good health and well-being.

The initiative is breaking the silence around PPD, a condition that can significantly impact new mothers in the critical period following childbirth.

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NCDC Monitors HMPV Situation, Affirms Nigeria at Moderate Risk

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HMPV

By Adedapo Adesanya

The Nigeria Centre for Disease Control (NCDC) says the country is at “moderate” risk for Human Metapneumovirus (HMPV), a virus that leads to an upper respiratory tract infection with symptoms like cough, fever, and nasal congestion.

In a public health advisory, the Nigerian health agency said the federal government is closely monitoring the outbreak of the virus and is taking safety measures to “strengthen the country’s preparedness and response capacity”.

Recent reports indicate a significant rise in HMPV cases in China, as well as increased respiratory infections linked to HMPV in countries such as the United Kingdom (UK), France, and Germany, particularly during the winter season.

The NCDC said it conducted a risk assessment for the HMPV in collaboration with the Federal Ministry of Health and partners such as the World Health Organization (WHO), the US Centres for Disease Control and Prevention (USCDC), and the UK Health Security Agency (UKHSA).

“The assessment classified the risk of HMPV for Nigeria as moderate. This evaluation will inform and guide preparedness efforts, decision-making, and response strategies to mitigate potential impacts,” the advisory said.

It said the NCDC is working to give Nigerians “timely, accurate information and guidance to keep the Nigerian public informed and prepared”.

NCDC noted that it “in collaboration with Port Health Authorities, is taking proactive steps to ensure robust preparedness at all international points of entry (PoEs) in response to the dynamic risk assessment for Human Metapneumovirus (HMPV).

“These measures are designed to mitigate the potential risk of HMPV transmission through international travel.”

HMPV was first identified in the Netherlands in 2001 and the virus spreads through direct contact between people or when someone touches surfaces contaminated with it.

Children under two are most vulnerable to the virus alongside those with weakened immune systems such as the elderly and those with advanced cancer, according to medical experts.

There have also been worries that this could be like COVID-19, but experts have eased the fear as they are not similar because pandemics are typically caused by novel pathogens, which is not the case for HMPV.

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Digitising Healthcare With Local Realities in Mind: Shaping The Future of Healthcare in Africa

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eHealth Africa (eHA) has urged governments and stakeholders to explore the critical factors beyond technology that are essential for the deployment of digital health solutions for the long-term success of public health systems across Africa. Data-backed interventions will help streamline operations and enable the formulation of interventions that appreciate the cultural norms when addressing the immediate needs of different communities within the region.

Speaking during a panel session at the Global Digital Health Forum 2024 in Nairobi, eHealth Africa’s Executive Director Atef Fawaz emphasised the importance of integrating technology with local cultures and addressing community-specific needs. “Understanding the unique healthcare challenges in each country allows us to deploy tech solutions that truly make an impact.”For instance, eHealth Africa successfully delivered over 5.8 million vaccines (5,801,209) to 351 primary healthcare facilities across states in Nigeria which was made possible through the deployment of the innovative Logistics Management Information System (LoMIS) application.

“The system significantly improved the availability of vaccines for Routine Immunisation (RI), ensuring timely and efficient distribution while eliminating stockouts at primary healthcare facilities. This intervention highlights our commitment to strengthening immunisation programs and enhancing healthcare delivery at the grassroots level,” he said.

In his contribution, Abdulhamid Yahaya, the Deputy Director of Global Health Informatics highlighted the need to understand the local cultural, social, and regulatory landscape to build solutions that are designed with local realities in mind.

eHealth Africa Board Member Micheline Ntiru said using technology provided stakeholders among them global health leaders, tech innovators, and development experts as well as local communities a platform to create the right solutions that work within the constraints of each community, and with the support of local leadership.

For instance, local health workers have been using mobile-based reminder systems to improve compliance and overall health outcomes while some local immunisation centres have been sending SMS reminders to parents as well as to provide educational messages about the diseases they protect against. Mobile phones, now available in nearly 80 per cent of African homes, can also be used during emergencies to dispatch mass announcements about satellite clinic locations and schedules.

According to the World Health Organisation, increased use of the Internet, email, social networking sites and availability of mobile phones facilitates the deployment of eHealth solutions, applications and services towards the improvement of national health systems. The use of technological eHealth solutions could also be used to encourage positive lifestyle changes to prevent and control common diseases.

The panel moderated by Ota Akhigbe, Director of Partnerships and Programs comprised of  Ms Ntiru (Delta40 ventures), Mr Yahaya (eHealth Africa), Chief Impact Officer at Tiko – Serah Malaba, Dr Olamide Okulaja (Maisha Meds), Audere Chief Executive Officer Dr Dino Rech, and  Rachel Alladian from Jacaranda. They discussed how strategic partnerships, regulatory compliance, and a deep understanding of local contexts are crucial for driving digital health innovations that can succeed in diverse regions.

The GDHF forum was attended by health scholars, researchers, and representatives from the Ministry of Health in Ethiopia, Tanzania, Kenya, Malaysia, Somalia and Sri Lanka as well as representatives from the World Bank, medicine manufacturers, technology vendors, UN agencies among others.

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