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Hepatitis E Outbreak in Niger Leaves 34 Pregnant Women Dead

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By Dipo Olowookere

In south-eastern Niger, the hepatitis E outbreak declared two months ago is particularly affecting pregnant women.

Of the 186 women admitted to the main maternal and paediatric health centre in the town of Diffa, 34 died of severe complications related to the disease.

Of the 876 cases of hepatitis E reported on June 11, the majority are displaced people and refugees, 247,900 according to the authorities.

As the disease spreads mainly through contaminated water, the current outbreak highlights poor water and sanitation conditions and the lack of adequate sanitation facilities among these people, already affected by the violence of the ongoing conflict between Boko Haram and the armies of the region.

Instability and lack of infrastructure

In Diffa, where access to healthcare has been hampered in particular by insecurity, the lack of adequate water, sanitation and hygiene infrastructure has an even greater impact on the health situation. Several sites within the displaced camps and communities do not have an adequate supply of drinking water, leaving some of the needs of the most vulnerable populations unmet. In addition, there is a lack of latrines, and those that are in place are in poor condition.

From the experience of other hepatitis E outbreaks in Africa, the Diffa one could last for several more months. The number of suspected cases may increase further in the near future, with the arrival of the rainy season, usually from June to September. “Given the scarcity of water for the most vulnerable populations, the risk is that alternative sources that can spread the outbreak will be used, such as the supply from streams and other natural water points formed by accumulated rain water. These collection points are considered as potential vectors of the disease”, explains Audace Ntezukobagira, emergency coordinator for MSF in Diffa. “It is also important to take into account that these people do not have the material or financial means to stock up on wood or gas, to boil the water in order to make it suitable for consumption”.

Water, hygiene and sanitation

To respond to the outbreak, one of the priorities is the strengthening of water and sanitation activities. However, the current response has not yet reached the standard required due to insufficient resources and coordination between humanitarian actors.

At certain sites, for example, it can be seen that jerry cans which are unsuitable for transporting water are not systematically collected when they are replaced. “This provokes a clear problem in terms of the risk of spreading the disease, as well as creating confusion as new jerry cans could be distributed several times in the same place”, says Sabiou Mansour, logistics manager for the MSF emergency team in Diffa. “It is deplorable, considering the efforts already provided in the region and the magnitude of the needs”.

Since April, MSF has strengthened its capacity to deploy emergency sanitation and hygiene measures at eleven sites. The teams working on more than 130 functional water points ensured that more than 6,300 m³ of water was chlorinated, 127,300 jerry cans were washed, nearly 3,400 old ones were replaced with new ones, and cleaning kits, including more than 36,800 soaps, were distributed.

For Sani Toubomrabo, a Nigerian community leader based in Garin Wazam, “the chlorinated water we bring home is useful to avoid getting sick, which is why we collaborate with the health agents present at the water points”.

Patient treatment

The response to the outbreak also includes free management of patients in health facilities at the community level and referral to hospital for those patients who develop complications.

In this respect, MSF teams are supporting the health authorities with human and material resources that have been deployed to deal with the situation. In addition to medical treatment, patients with hepatitis E receive psychological support. The organisation also provides technical support for health staff in the structures in which it operates in order to ensure free and high-quality care for patients. A decrease in mortality was also observed among women with severe complications related to the disease admitted to the main maternal and paediatric health centre in the town of Diffa.

Awareness-raising in the heart of the community

Health promotion activities in the health facilities and the community have also been set up by MSF. To date, nearly 32,000 people have been informed, including patients and their families. At the same time, MSF is actively looking for cases in villages, which has already led to the referral of more than 400 people to health centres.

MSF in Diffa

Since the end of 2014, MSF has been working in the Diffa region to help those fleeing violence related to the presence of the Boko Haram group and military intervention in the region. MSF provides free medical and psychological assistance in seven health centres in the region. In addition, the organisation supports the supply of drinking water supply, the construction of latrines and the distribution of essential items in several villages and places where refugees, returnees and displaced people have gathered.

In addition, MSF is supporting the Ministry of Health in two hospitals: the Nguigmi Hospital and the main maternal and child health centre in the Diffa town. In both hospitals, MSF is working in reproductive and paediatric health units, and provides mental health support. At the hospital in Nguigmi, the team also treats children suffering from severe acute malnutrition.

Dipo Olowookere is a journalist based in Nigeria that has passion for reporting business news stories. At his leisure time, he watches football and supports 3SC of Ibadan. Mr Olowookere can be reached via [email protected]

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Resident Doctors Suspend Proposed Indefinite Strike

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Resident Doctors

By Adedapo Adesanya

The Nigerian Association of Resident Doctors (NARD) has suspended its planned indefinite strike following the federal government’s reversal of the implementation of the reviewed Professional Allowance Table (PAT) and renewed assurances on outstanding payments.

The decision was announced in a communiqué issued at the end of an emergency National Executive Council (NEC) meeting held virtually on Saturday.

NARD had earlier resolved to embark on a total and indefinite strike over the government’s suspension of the reviewed allowance structure and other unresolved welfare concerns affecting resident doctors nationwide.

However, the association said it reconsidered its position after reviewing the outcomes of high-level engagements with key government officials and health-sector stakeholders.

According to the communiqué signed by NARD President, Dr Mohammad Usman Suleiman; Secretary-General, Dr Shuaibu Ibrahim; and Publicity and Social Secretary, Dr Abdulmajid Yahya Ibrahim, the Federal Government has now reversed its earlier decision on the allowance table.

“The NEC observed that the earlier decision to halt the implementation of the reviewed Professional Allowance Table (PAT) has been reversed, with implementation expected to reflect in the April salary and beyond,” the statement read.

The association also noted the government’s renewed commitment to settling outstanding promotion and salary arrears owed to resident doctors in affected institutions.

In addition, NARD said initial approval had been secured for the 2026 Medical Residency Training Fund (MRTF), with assurances that the disbursement process would be concluded.

“The NEC observed that the Budget Office has indicated its readiness to commence the process for the payment of the outstanding nineteen months’ arrears of the Professional Allowance,” the communiqué added.

Despite the progress, the doctors expressed concern about the continued delay in paying house officers’ salaries and called for urgent action to address the issue.

Following its deliberations, the NEC demanded the sustained implementation of the reviewed allowance structure, the prompt payment of all outstanding arrears, and the expedited disbursement of the residency training fund.

It also called for the immediate commencement of the process to clear the 19-month arrears and the convening of an urgent stakeholders’ meeting to resolve delays affecting house officers’ salaries.

“In light of the above developments, the NEC resolves to suspend the proposed total, indefinite, and comprehensive strike action, with a review of progress to be undertaken at the May Ordinary General Meeting (OGM) in Kano,” the statement said.

NARD expressed appreciation to President Bola Tinubu, Vice President Kashim Shettima, and several ministers, government agencies, and stakeholders for their interventions in resolving the dispute.

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Over 1.5 million Nigerian Children Living With Sickle Cell Disease—Report

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sickle cell disease

By Modupe Gbadeyanka

More than 1.5 million children under the age of 15 are living with sickle cell disease in Nigeria, a new international study published in The Lancet Child & Adolescent Health, one of the world’s leading medical journals, has revealed.

In the report made available to Business Post, it was disclosed that Nigeria carries the highest burden of disease globally, far exceeding other high-burden countries such as the Democratic Republic of the Congo and Ethiopia.

The findings highlight both the scale of the challenge in Nigeria and the opportunity for the country to lead Africa in tackling one of the most preventable causes of childhood illness and death.

The study shows that nearly nine million children across sub-Saharan Africa are living with sickle cell disease in 2023, including around 1.17 million infants and 2.75 million children under five, who face the highest risk of early death without treatment.

Sickle cell disease is an inherited blood disorder present at birth. With early diagnosis and access to simple, low-cost interventions such as newborn screening, penicillin prophylaxis, routine vaccinations, malaria prevention, and hydroxyurea, most complications and deaths can be prevented.

However, in Nigeria, access to these essential services remains limited. Many children are only diagnosed after severe and avoidable complications, while others are never diagnosed at all, contributing to high levels of preventable illness and early childhood deaths.

The researchers emphasise that strengthening Nigeria’s health system response will be critical. This includes expanding newborn screening programmes, improving access to essential medicines, and integrating sickle cell care into primary healthcare services.

They called for urgent and coordinated action across government, health institutions, and development partners, including expanding newborn screening programmes, improving access to essential medicines and vaccines, and embedding sickle cell care within primary healthcare services.

The researchers, led by Professor Davies Adeloye, Professor of Public Health at Teesside University, United Kingdom, and Director of the International Society of Global Health (ISoGH), also called for increased domestic investment, supported by international partnerships, as well as stronger data systems to improve surveillance and guide policy decisions.

They concluded that even modest improvements in early-life screening and treatment in high-burden countries like Nigeria could transform child survival and significantly reduce preventable deaths.

“Nigeria now stands at the centre of the global sickle cell crisis. With over 1.5 million children affected, the scale is enormous, but so is the opportunity to act. We already know what works. Newborn screening and early treatment are effective, affordable, and can be delivered through existing health systems.

“If Nigeria prioritises sickle cell disease within its national health agenda and integrates care into routine maternal and child health services, we could save hundreds of thousands of young lives and significantly reduce avoidable deaths.” Professor Adeloye noted.

It was learned that the study analysed data from 40 studies across 22 African countries to produce the most comprehensive country-level estimates of childhood sickle cell disease to date.

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Health

Helical Secures $10m Funding Package for Expansion

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Helical

By Dipo Olowookere

A $10 million capital has been raised by Helical to support expansion across more top-20 pharma programmes and growth of its deployed science engineering team.

The firm will also use the money to build the compounding evidence layer that improves performance across diseases, as its mission is to make every scientist able to test hypotheses at the speed of inference and to turn in-silico discovery into a reliable engine for R&D throughput.

The funding package was from redalpine, Gradient, BoxGroup, Frst and notable angels, including Aidan Gomez (CEO Cohere), Clement Delangue (CEO HuggingFace) and Mario Goetze (pro soccer player).

Helical has a product known as the virtual AI lab for pharma, an application layer that turns biological foundation models into decision-ready, reproducible in-silico discovery workflows.

The platform has two product surfaces — the Virtual Lab for biologists and translational scientists, and the Model Factory for ML engineers and data scientists — built on the same data, the same models, and the same results.

By putting both sides in the same system, Helical closes the gap between computational predictions and biological decision-making, so teams that traditionally worked in silos can collaborate on the same evidence.

Helical was founded in early 2024. It was created by three school friends who took different paths to the same problem.

Rick Schneider built tech at Amazon and later helped the German enterprise Celonis scale in France and Japan. Maxime Allard led data science teams at IBM before pursuing a PhD focused on reinforcement learning and robotics. Mathieu Klop became a cardiologist and genomics researcher.

When bio foundation models emerged, the trio saw the chance to build the missing application layer that would let pharma teams move from model experimentation to reproducible, production discovery.

“The models alone don’t discover drugs. The system does. Pharma teams need a system that turns foundation models into workflows scientists can run, validate, and defend.

“We built Helical to make in-silico science reproducible at pharma scale, so teams can go from hypothesis to decision in days instead of months,” the co-founder of Helical, Mr Rick Schneider, said.

“We are at a unique point in time where biological foundation models and general language reasoning models are converging.

“We backed Helical because we strongly believe they have what it takes to build the pharma AI orchestration platform that will drive this transition from siloed AI models to integrated virtual AI labs,” the General Partner at redalpine, Mr Daniel Graf, stated.

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