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Tiotropium Respimat Improves Lung Function In Asthmatic Children

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Tiotropium Respimat

By Modupe Gbadeyanka

Boehringer Ingelheim announced today new study results from the Phase III CanoTinA-asthma® trial showing that the addition of Tiotropium Respimat® to the maintenance asthma therapy significantly improved lung function, as measured by FEV1(0-3h), in children aged 6-11, compared to placebo (p<0.0001).1

These findings were presented today at the European Respiratory Society (ERS) International Congress 2016 in London.

The trial investigated tiotropium Respimat® as an add-on therapy for children who were already taking an inhaled corticosteroid (ICS), or an ICS combined with other maintenance therapy.1,2 In this study, the safety and tolerability of tiotropium Respimat® were shown to be comparable to placebo.

“Asthma is the most common chronic childhood disease, but many children still continue to experience asthma symptoms despite taking other maintenance therapies,” said Professor Christian Vogelberg, University Hospital Dresden, Germany.

A new pooled analysis from four studies, VivaTinA-asthma®, RubaTinA-asthma®, PensieTinA-asthma® and CanoTinA-asthma® also presented at ERS, showed adding tiotropium Respimat® to maintenance therapy for children aged 6-17 years has a comparable safety profile to placebo.3 In addition, this analysis showed tiotropium Respimat® significantly improved peak expiratory flow (PEF), a common measure of asthma control.

“These new results showed significant lung function improvements for children with asthma and importantly confirm that the safety profile of tiotropium Respimat® in children aged six years and above is comparable to placebo,” said Professor Vogelberg.

In the important subgroup of children aged 1-5, a new post-hoc analysis presented from the NinoTinA-asthma® trial showed the safety profile of adding tiotropium Respimat® to maintenance therapy is consistent with that found in older children and adults.

The CanoTinA-asthma®, NinoTinA-asthma®, VivaTinA-asthma®, RubaTinA-asthma® and PensieTinA-asthma® trials are part of the 18 clinical studies from the Phase II and Phase III UniTinA-asthma® clinical development program, which included more than 150 sites globally with over 6,000 patients, including over 1,800 children and adolescents aged 1-17 years.

“At Boehringer Ingelheim, we have a strong commitment to scientific research with the goal of improving the care of people living with serious respiratory diseases such as asthma,” said Dr William Mezzanotte, Vice President and Head of Respiratory Medicine at Boehringer Ingelheim. “Data from these studies build on the body of evidence that we have learned about tiotropium Respimat® as an add-on therapy for asthma.”

SPIRIVA® (tiotropium) Respimat® 5µg is indicated in Europe as an add-on maintenance bronchodilator treatment in adult patients with asthma who are currently treated with the maintenance combination of ICS (≥800µg budesonide/day or equivalent) and long-acting β2 agonists (LABA) and who experienced one or more severe exacerbations in the previous year.

Tiotropium is an inhaled long-acting, muscarinic antagonist. It works by opening airways and helps to keep them open for at least 24 hours.

SPIRIVA® Respimat® is currently NOT APPROVED for use in children and adolescents under 18 years of age in the EU, or in children under 12 years in the US. SPIRIVA® Respimat® has been approved for use in asthma in over 50 countries, including the EU, US and Japan. The indication varies by country. Please refer to the local product information.

Dipo Olowookere is a journalist based in Nigeria that has passion for reporting business news stories. At his leisure time, he watches football and supports 3SC of Ibadan. Mr Olowookere can be reached via [email protected]

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Nigeria Launch €4.2m Initiative to Boost Capacity Against Outbreaks

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By Adedapo Adesanya

Nigeria has launched a €4.2 million programme supported by the European Union (EU) and implemented by the World Health Organisation (WHO) to strengthen the country’s capacity to detect and respond to disease outbreaks.

The initiative, known as the EU Support to Public Health Institutes in Nigeria (EU SPIN), will be carried out over four years in partnership with the Federal Ministry of Health and Social Welfare.

It is aimed at improving the performance of selected public health institutions through better coordination, faster information sharing and enhanced workforce capacity.

Speaking at the launch in Abuja on Monday, the Minister of State for Health and Social Welfare, Mr Iziaq Adekunle Salako, described the programme as a significant step towards strengthening Nigeria’s healthcare system.

“This initiative is designed to strengthen our health institutions, and it is truly a welcome development. It will improve the well-being of Nigerians, especially our vulnerable populations,” he said, noting that it aligns with the federal government’s broader health reform agenda.

Nigeria continues to face a dual health burden, with recurring infectious disease outbreaks alongside a growing prevalence of non-communicable diseases such as hypertension and diabetes.

According to the WHO, non-communicable diseases now account for 27 per cent of deaths in the country, while malaria alone contributes about 30 per cent of global malaria fatalities.

Recurrent outbreaks of cholera, diphtheria, Lassa fever, meningitis and Mpox also remain a major public health concern.

The EU SPIN programme is expected to address systemic gaps that slow outbreak response by strengthening collaboration among public health institutions and clarifying roles across federal, state and local levels.

It will also support real-time data systems to enable quicker and more informed decision-making during health emergencies.

A key component of the initiative is workforce development, with plans to train up to 75 per cent of public health staff in leadership, prevention and response strategies, as well as digital skills.

The European Union Ambassador to Nigeria, Mr Gautier Mignon, said the programme reflects a shared commitment to building resilient health systems.

“Through EU SPIN, the European Union is investing in strong, digitally enabled public health institutions in Nigeria. This partnership underscores our commitment to health security and sustainable systems strengthening,” he said.

Also speaking, the WHO Representative in Nigeria, Mr Pavel Ursu, noted that improved coordination and digital tools would enhance the country’s ability to protect lives.

“By improving coordination, skills and digital tools, the project will help protect lives and keep communities healthier,” he said.

Officials said the programme would ultimately strengthen links between public health systems and primary healthcare services, ensuring that communities benefit from faster and more effective responses to health threats.

By 2028, the initiative is expected to deliver more efficient inter-agency coordination, clearer institutional responsibilities and more reliable public health data nationwide, with progress tracked through national monitoring systems and periodic reviews involving government and development partners.

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Malaria: SUNU Health Advocates Wider Adoption of HMO Plans

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By Aduragbemi Omiyale

To achieve a malaria-free Nigeria, a leading Health Maintenance Organisation (HMO) with a robust nationwide presence, SUNU Health Nigeria Limited, has called for a wider adoption of HMO packages for citizens.

It stressed that managed care provides a critical safety net, ensuring families can access quality preventive services without the burden of immediate, high costs, adding that this structured approach transforms healthcare from an unpredictable expense into a manageable, guaranteed service.

The company, which officially unveiled a comprehensive strategic roadmap aimed at drastically cutting down on malaria-related deaths, emphasised that the disease can be eradicated if citizens and stakeholders adopt consistent preventive measures.

“Eradication is within our reach if we synchronise our efforts,” the chief operating officer of SUNU Health, Dr Faith Nwachi, said, noting that the tools for victory range from environmental hygiene to the consistent use of treated nets, which are easily accessible to every Nigerian.

The organisation noted that it came up with the latest framework to significantly reduce the disease burden that has historically hindered Nigeria’s productivity and public health stability.

The urgency of this intervention is underscored by concerning data from late 2025, which revealed a sharp upward trend in cases, it stated.

With over 24.5 million confirmed cases reported in the first nine months of last year alone, the 2026 landscape demands aggressive action. Currently, malaria remains a leading cause of mortality, responsible for approximately 30 per cent of child deaths and 11 per cent of maternal deaths annually.

A central pillar of the roadmap is a focus on preventative care. As of early 2026, according to the World Health Organisation, malaria still accounts for nearly 30 per cent of all hospital admissions in Nigeria.

By addressing the root causes and transmission cycles, SUNU Health seeks to drastically lower these statistics, ensuring Nigerians can lead more active lives without the constant threat of infection.

Dr Nwachi further underscored the economic necessity of this shift, stating that “prevention is significantly cheaper than cure.”

The financial toll on the Nigerian economy is staggering, with billions of Naira lost annually to treatments and diminished man-hours. For the average family, frequent bouts of illness lead to catastrophic out-of-pocket expenses that undermine financial security.

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AltBank, Partners Recommend Autism Care Financing Options, Others to Government

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Autism Care Financing Options

By Aduragbemi Omiyale

Plans are underway by the Alternative Bank (AltBank) to present a policy brief to relevant government ministries, recommending vocational pathways, autism care financing options, and a 12-month Lagos pilot across selected schools and primary healthcare centres.

The recommendations are from the inaugural Autism Stakeholders Roundtable and Policy Dialogue in Lagos, organised by the lender in partnership with the Private Sector Health Alliance of Nigeria (PSHAN), Eliakim Foundation, and Sterling One Foundation under the theme, It is How You Show Up.

The programme served as a critical platform to address the country’s fragmented autism support systems, with leading healthcare professionals, policymakers, and autism advocates in attendance, praising the financial institution’s decisive shift toward early intervention, systemic inclusion, and comprehensive capacity building for parents and caregivers.

The president of the Medical Women’s Association of Nigeria (MWAN) Lagos State Branch, Dr Ime Okon, stressed her group’s alignment with the bank’s initiatives.

“We recognise caregivers and families as central to the success of any intervention. We are showing up, holding their hands, to ensure they are never left to navigate this journey alone.

“For a physician, showing up means ensuring that a parent’s first concern is met with a strengthened, inclusive system rather than a clinical dead-end with no solution. The Alternative Bank has signalled a shift toward a high-level platform for national action,” she stated.

Validating this urgent need for systemic early response, the keynote speaker and founder of the Patrick Speech and Languages Centre (PSLC), Mrs Dotun Akande, advocated the integration of universal developmental screening into primary healthcare, stressing that Nigeria must transition from relying on parallel private centres to building a coordinated national response.

“What Nigeria must now build is a system where intervention happens early, equitably, and at scale, without depending on chance, geography, or privilege,” Mrs Akande noted, outlining the necessity of a caregiver support scheme that addresses both the financial and social needs of families navigating autism.

Answering this call to action, the Executive Director of Commercial and Institutional Banking (Lagos and Southwest) at The Alternative Bank, Mrs Korede Demola-Adeniyi, unveiled the financial institution’s concrete commitments to parent and professional training.

Noting that showing up in Nigeria has “too often meant showing up late,” she announced a robust three-pillar intervention agenda focusing on inclusive education, targeted training for caregivers and health professionals, and behavioural change advocacy.

As an immediate first step, Mrs Demola-Adeniyi announced the launch of a specialised capacity-building programme on Receptive Language Disorder, executed in collaboration with Eliakim Global Resources, which commenced on Sunday, April 26, 2026.

“Early recognition and sustained support depend on a workforce and caregivers who know what to look for, and what to do next,” she explained, emphasising that receptive language is a consequential developmental marker that is frequently missed.

The roundtable fostered dynamic discussions on practically designing and sustainably funding high-impact support programmes.

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