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Octa Broker Analysis: Why the U.S. Dollar is Struggling Amid Global Trade Turmoil

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KUALA LUMPUR, MALAYSIA – Media OutReach Newswire – 29 April 2025 – The U.S. Dollar, the world’s reserve currency and the ultimate safe-haven asset, is now the world’s worst-performing major currency in 2025. Octa Broker explains why. The historical role of the U.S. dollar as the world’s leading safe-haven currency is under threat. Despite rising macroeconomic uncertainty, investors are fleeing the U.S. dollar, defying conventional safe-haven flows. Greenback’s rapid depreciation over the past weeks has fuelled speculation over the loss of confidence in its safe-haven status. With USDCHF trading news multi-year low, Octa Broker analyzes if we are in the midst of dramatic regime change in markets and explains why the U.S. dollar is struggling amid global trade turmoil.

The U.S. dollar (USD), the buck or the greenback, as it is often informally referred to, has long occupied a rather exclusive position in global finance. Ever since the end of World War II and the establishment of the Bretton Woods monetary system, the greenback has played a crucial role in facilitating cross-border transactions and smoothing international trade flows, in addition to serving as a primary reserve currency for central banks around the world. Being the official currency of the world’s largest economy, the United States, has certainly helped the dollar maintain its dominant position. Indeed, the sheer size of the U.S. economy, its deep and liquid financial markets, strong private property rights and the rule of law enshrined in the U.S. Constitution, and last but not least, the unrivalled power of the U.S. military, made the dollar the most trusted global currency. As a result, the greenback became what market participants call ‘a safe-haven currency’, a refuge for investors during times of macroeconomic uncertainty or market turmoil. Most recently, however, the instability in global financial markets triggered by rising trade tariffs and exacerbated by fears of a global recession seems to have upended this narrative, undermining the dollar’s established role.

Trade tensions
The U.S. dollar has been depreciating almost relentlessly since mid-January. In just three and a half months, the Dollar Index (DXY), which measures the value of the greenback relative to a basket of six major foreign currencies, including the euro, Japanese yen, British pound, Canadian dollar, Swedish krona, and Swiss franc, lost more than 10% in value (from 13 January high to 21 April low). On 11 April, it breached the critical 100.00 level, and although it has since increased slightly, it remains by far the worst-performing currency among other major currencies this year so far. This decline has raised an important question: Is the U.S. dollar losing its safe-haven status, or is it merely a temporary setback.

The catalyst for the dollar’s slide is rooted in the escalating trade tensions, particularly the aggressive tariff policies enacted by U.S. President Donald Trump. In recent weeks, the U.S. imposed a 10% baseline tariff on all imports, with much steeper duties imposed on key trading partners like China, which, in turn, retaliated with its own 125% levies on U.S. goods. These moves have stoked fears of a global recession, as international supply chains may get disrupted with potentially devastating consequences for the world economy. Historically, such uncertainty would bolster the dollar, as investors seek the safety of U.S. assets. However, this time around, the greenback is faltering, while alternative safe-haven currencies like the Swiss franc (CHF) and Japanese yen (JPY) are gaining ground.

Hedging
Kar Yong Ang, a financial market analyst at Octa Broker, says that the U.S. dollar’s recent weakness is driven by a diversification shift among investors into alternative safe-haven currencies, motivated by risk-hedging and fears over the growth prospects of the U.S. economy. ‘We are witnessing a major reallocation of capital. Market participants realise that in a trade war, there are no winners. In the short term, the U.S. economy will face the consequences, and they will not be pretty. Big players with large investments in the U.S. realised they needed to hedge their currency risk, so they moved into the Swiss franc and the Japanese yen. Also, higher tariffs are fuelling recession fears, so traders have increased their bets on additional rate cuts by the Fed [Federal Reserve]. That too had a bearish effect on the greenback’.

Indeed, on April 21, USDCHF dropped below the 0.80500 mark, the level unseen in almost 14 years, while USDJPY was hovering near the critical 140.00 area, a drop below which will open the way towards new multi-year lows. Significant shifts in capital flow allocations have prompted some analysts to conclude that the U.S. dollar is facing a crisis of confidence. However, Octa analysts have a different view and believe that the current situation doesn’t reflect a broad erosion of investors’ long-term trust in the U.S. dollar. Kar Yong Ang said: ‘The issue isn’t so much a fundamental loss of faith in the U.S. dollar’s long-term prospects. What we are witnessing right now is a dramatic, yet logical response to the probable economic implications of Donald Trump’s trade policies. You have an administration, which is effectively re-structuring the global trade order, that does not conceal its dissatisfaction with the Fed and apparently believes in a weak dollar. If you’re a foreign investor in the U.S., you simply cannot afford to be unhedged these days. But also, let’s not forget that the greenback has been falling from relatively high levels, so a healthy downward correction was long overdue’. In other words, the recent slide in the U.S. dollar is not an unusual phenomenon or an anomaly; it is quite natural and probably a short-term occurrence. In fact, even after an 11% drop in 2025, the greenback is still some 38% above its historical low set in 2008. Furthermore, it is clear that once key global actors adopt more conciliatory diplomatic rhetoric and engage in active trade negotiations, the situation will normalise immediately.

Conclusion
As for the dollar’s long-term prospects, its dominant status will likely continue to be challenged, but no single currency can take its crown for now. According to the Bank of International Settlements (BIS), the U.S. dollar still accounts for nearly 88% of international transactions, and its dominance in Forex markets remains unmatched, with daily trading volumes dwarfing those of the yen or franc. According to the International Monetary Fund (IMF), more than half (57.8%) of the $12.4 trillion in global foreign exchange reserves were in U.S. dollars. Therefore, while the greenback may not be the automatic refuge it once was, its role as a Forex cornerstone endures for now.

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Octa

is an international CFD broker that has been providing online trading services worldwide since 2011. It offers commission-free access to financial markets and various services used by clients from 180 countries who have opened more than 52 million trading accounts. To help its clients reach their investment goals, Octa offers free educational webinars, articles, and analytical tools.

The company is involved in a comprehensive network of charitable and humanitarian initiatives, including the improvement of educational infrastructure and short-notice relief projects supporting local communities.

In Southeast Asia, Octa received the ‘Best Trading Platform Malaysia 2024’ and the ‘Most Reliable Broker Asia 2023’ awards from Brands and Business Magazine and International Global Forex Awards, respectively

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St. George’s University Prepares Future South Korean Physicians for the Growing Global Cancer Care Challenge

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SEOUL, SOUTH KOREA – Media OutReach Newswire – 4 February 2026 – Rising global cancer incidence is straining healthcare systems, which already face workforce shortages. In East Asia, the number of trained physicians in cancer care, spanning diagnosis, treatment coordination, and long-term management—has not met the increasing demand. According to the Global Cancer Observatory, South Korea reported over 230,000 new cancer cases and more than 97,000 fatalities in 2022. A recent original academic research by Myongji College and The Catholic University of Korea warned that simply increasing medical school enrollments alone does not fix shortages in key specialties and underserved regions where medical demand is rising fastest.

Source: St. George’s University

Recognizing the importance of addressing workforce shortage in South Korea, St. George’s University (SGU) School of Medicine in Grenada, West Indies, highlights how its medical education approach supports the development of clinical competencies relevant to cancer care across healthcare settings.

These challenges reflect broader global trends, where cancer care increasingly depends on multidisciplinary teams rather than specialty expansion alone. SGU’s curriculum is designed to build a strong foundation in clinical diagnosis, patient communication and multidisciplinary care, which are essential skills for effective oncology and cancer-related care. Through anatomy labs, simulation-based learning, and integrated digital tools, students develop foundational clinical skills in structured, supervised environments designed to reflect real-world medical practice.

The curriculum also integrates traditional cadaveric dissection with modern 3D anatomical modeling. This blend helps students visualize the human body in a holistic way while reinforcing knowledge through their hands-on interaction. SGU’s simulation lab also enables medical students to have their first direct interaction with ill patients in a safe, simulated learning environment.

On top of core medical training, SGU offers early exposure to prevention, diagnosis and patient-centered care to prepare graduates to tackle complex health issues. SGU has developed long-standing relationships with more than 75 established hospitals and clinical centers in the US and UK. These clinical placements provide exposure to diverse patient populations and care environments, including settings where cancer diagnosis and management are part of routine clinical practice.

South Korean SGU alumni are contributing to healthcare systems through roles that intersect with cancer diagnosis, treatment coordination, and long-term patient care. For example, Dr. Julia Hweyryoung Cho, MD 2022 is practicing internal medicine, which plays a crucial role in cancer care. Internal medicine physicians are often involved in the initial diagnosis of cancer, managing complex medical conditions that may arise during treatment and providing long-term comprehensive care and survivorship planning for patients with a history of cancer.

In observance of World Cancer Day 2026, SGU encourages all medical professionals and organizations to collaboratively address global cancer care challenges. This includes recognizing and meeting the cancer healthcare needs of individuals and communities in South Korea.

For more information on the programs and tracks available through SGU School of Medicine, visit SGU’s website.Hashtag: #St.George’sUniversity

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Finalists and Semifinalists for $1 Million Seeding The Future Global Food System Challenge Announced

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BONN, GERMANY – Newsaktuell – 3 February 2026 – The Seed Grant Finalists and Growth Grant and Seeding the Future Grand Prize Semifinalists of the 5th annual Seeding The Future Global Food System Challenge (GFSC) have been announced, marking a key milestone in the USD 1 million global Challenge supporting impactful and innovative solutions to transform food systems.

Created and funded by Seeding The Future Foundation and, for the first time, hosted by Welthungerhilfe (WHH), the Challenge attracted a record 1,600+ applications from innovator teams in 112 countries, underscoring growing global momentum for food systems transformation.

Following a multi-stage, rigorous international review process, 36 teams have advanced across three award levels. These include 16 Seed Grant Finalists (competing for 8 awards of USD 25,000), 12 Growth Grant Semifinalists (competing for 3 awards of USD 100,000), and 8 Seeding The Future Grand Prize Semifinalists (competing for 2 awards of USD 250,000).

“Hosting the GFSC reflects Welthungerhilfe’s commitment to accelerating bold, scalable innovations where they are needed most. This year’s diversity of solutions underscores the complexity of food system challenges and the creativity of innovators worldwide.” said Jan Kever, Head of Innovation at Welthungerhilfe

The submitted innovations span diverse themes and approaches, including climate-smart production, nutrient-dense foods, food loss reduction, and inclusive market models, reflecting the complexity and interconnected nature of today’s food systems challenges.

“The Seeding The Future Global Food System Challenge exists to catalyze impactful, bold, and scalable innovations that advance food systems transformation. We are excited to work alongside Welthungerhilfe as a trusted partner and host of the Challenge and are encouraged by the quality and diversity of innovations emerging from this first year of collaboration.” said Bernhard van Lengerich, Founder and CEO of Seeding The Future Foundation

While the number of awards is limited, all semifinalists and finalist applicants plus all applicants with any prior recognition of other innovation competitions can join the STF Global Food System Innovation Database and Network—currently in beta testing with the Food and Agriculture Organization of the United Nations—vastly expanding their visibility and reach across a global audience.

List of 2025 GFSC Seed Grant Finalists, Growth Grant and Seeding The Future Grand Prize Semifinalists

Find details here: welthungerhilfe.org/gfsc-finalists

Seeding The Future Grand Prize Semi-Finalists

Growth Grant Semi-Finalists

Seed Grant Finalists

Hashtag: #TheFutureGlobalFoodSystemChallenge

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About Seeding The Future Foundation

STF is a private nonprofit dedicated to ensuring equitable access to safe, nutritious, affordable, and trusted food. It supports innovations that transform food systems and benefit both people and planet. More at .

About Welthungerhilfe
WHH is one of Germany’s largest private aid organizations, striving for a world without hunger since 1962. More at:

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PolyU develops novel antibody targeting fat cell protein, offering new approach to treating metabolism-related liver cancer

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HONG KONG SAR – Media OutReach Newswire – 3 February 2026 – Liver cancer is one of the three deadliest cancers worldwide, and metabolic dysfunction-related cases have become increasingly common in recent years. A research team from The Hong Kong Polytechnic University (PolyU) has identified a protein secreted by fat cells that promotes cancer growth and has successfully developed a novel antibody that neutralises this protein, marking a significant breakthrough in impeding the progression of liver cancer. The research findings have been published in the Journal of Clinical Investigation.

Prof. Terence Lee, Associate Head and Professor of the PolyU Department of Applied Biology and Chemical Technology, and his research team have developed a novel antibody targeting the adipocyte-derived protein FABP4, offering a new approach to treating metabolism-related liver cancer.

Metabolic dysfunction-associated steatotic liver disease (MASLD), commonly known as fatty liver disease, currently affects around a quarter of the global population and is an important risk factor for liver cancer. In affected individuals, fat cells induce insulin resistance and chronic inflammation, leading to excessive fat accumulation in the liver. This ultimately impairs liver function and may progress to liver cancer. Treatment options for MASLD-induced liver cancer remain limited and the effectiveness of current immunotherapies is suboptimal.

A breakthrough study led by Prof. Terence LEE, Associate Head and Professor of the PolyU Department of Applied Biology and Chemical Technology, and his research team has revealed that an adipocyte-derived protein, known as fatty acid-binding protein 4 (FABP4) is a key driver that accelerates tumour growth. Through mass spectrometry, the team confirmed that patients with MASLD-induced liver cancer had markedly elevated FABP4 levels in their serum. Further investigations showed that FABP4 activates a series of pro-proliferative signalling pathways within cells, causing cancer cells to multiply and grow more rapidly.

Prof. Lee’s team has successfully developed a monoclonal antibody that neutralises FABP4. This antibody not only inhibits the growth and proliferation of FABP4-driven cancer stem cells, but also enhances the ability of immune cells to combat cancer.

Prof. Lee said, “This neutralising antibody against FABP4 demonstrates significant potential in inhibiting tumour growth and activating immune cells, providing a complementary approach to current immunotherapy strategies. Our findings highlight that targeting adipocyte-derived FABP4 holds promise for treating MASLD-induced liver cancer.”

Prof. Lee added that gaining deeper insights into how adipocyte-derived FABP4 affects liver cancer cells helps to explicate the disease mechanisms of liver cancer, particularly in obese individuals. Intervening in the relevant signalling pathways could provide effective methods to combat this aggressive malignancy.

Prof. Lee believes that, as this adipocyte-targeted immunotherapy continues to mature, it will bring more treatment options to MASLD patients. He remarked, “If its efficacy can be proven in clinical trials, it could offer new hope to many affected individuals.”

The research is supported by the Innovation and Technology Fund of the Innovation and Technology Commission of the Government of the Hong Kong Special Administrative Region of the People’s Republic of China. PolyU has filed a non-provisional patent for the developed antibody and is continuing to optimise its binding affinity to facilitate future clinical applications.
Hashtag: #PolyU #FattyLiver #Cancer #LiverCancer #理大 #香港理工大学 #肝癌 #癌症 #脂肪肝

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