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54Gene Launches Clinical Research Program in Nigeria

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54Gene

By Adedapo Adesanya

Abuja-based healthcare startup, 54gene, has launched its Clinical Program Services (CPS) division, which will provide end-to-end clinical development services, intelligence, logistics, and infrastructure and ultimately enable successful conduct of clinical trials in Africa, starting from Nigeria.

The launch comes at the same time as the appointment of 54gene as the Nigerian country partner for the International Registry of Healthcare Workers Exposed to COVID-19 (UNITY Global) Study.

In partnership with Certara, a global leader in biosimulation, the startup will provide clinical trial management oversight and support for all aspects of the study conducted in Nigeria.

54gene’s Clinical Program Services division is focused on partnering with global pharmaceutical and biotechnology companies, and multilateral health organisations to discover, develop and commercialize new therapeutic and diagnostic products, the company said in a press release.

The research division is led by Mrs Kemi Williams, the Vice President of Clinical and Regulatory Affairs, who brings years of driving clinical excellence, delivering regulatory competency, and ensuring operational efficiency to the company.

On the launch of the Clinical Program Services division, 54gene Chief Commercial Officer, Mrs Jessica Rich, said, “The inclusion of Africans in clinical programs is critical to the production of medicines and health products that are more efficacious and safe for people of African descent.

“It is vital that we continue to collaborate with African researchers and institutions to generate data that meets the scientific rigour found in worldwide studies and to increase African inclusion in global studies. It is essential that more research takes place on the continent and we are ready to be part of that change.

“Alongside key partners like Certara and other important stakeholders across the continent, the UNITY Global Study is a great opportunity for some of the best clinical teams across Sub-Saharan Africa to come together and ensure outcomes of any COVID-19 studies are relevant to Africans.

“The insights generated from this program could potentially unlock breakthrough clinical discoveries that can improve health outcomes for millions of people globally.”

The UNITY Global study aims to develop prevention policies based on real-world data collected from 10,000 healthcare workers in low and middle-income countries, including Pakistan, Nigeria, South Africa, Kenya, Uganda, Senegal, Zambia, and Zimbabwe.

The registry’s primary objective is to examine the link between the use of preventive treatments and the occurrence of SARS-CoV-2 infection in healthcare workers providing care to patients with COVID-19.

With the nature of the virus and its impact on the global healthcare system, it is crucial to develop guidance and policies for protecting healthcare workers, who are at the frontline of combating the disease.

The registry will collect information on a weekly basis from enrollees across a 12-week period. Data collection includes medications being taken by healthcare workers, their level of exposure to COVID-19 patients, their health status, and other factors such as the use of personal protective equipment (PPE), which would likely mitigate their risk of SARS-CoV-2 infection.

In addition, the registry will record SARS-CoV-2 antibody test results. The study is funded by a grant from the COVID-19 Therapeutics Accelerator.

On his part, Mr Roman Casciano, general manager of Certara’s evidence and access group added: “Healthcare workers have a high incidence of severe COVID-19 as they are repeatedly exposed to individuals infected with SARS-CoV-2.

“With limited evidence on the effectiveness of the preventative measures and treatments currently being used, collaborating with key partners such as 54gene is invaluable for expanding the current body of research.”

“Through our country partners’ support and findings from the registry, we hope to provide meaningful data to inform decision making that will help protect healthcare workers worldwide battling COVID-19 on the frontlines.”

Adedapo Adesanya is a journalist, polymath, and connoisseur of everything art. When he is not writing, he has his nose buried in one of the many books or articles he has bookmarked or simply listening to good music with a bottle of beer or wine. He supports the greatest club in the world, Manchester United F.C.

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Oyo Raises Entry Grade Level for University Graduate Nurses to 10

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graduate nurses ibadan

By Modupe Gbadeyanka

The entry grade level for nurses in the Oyo State civil service with university degree has been reviewed, the Provost of the Oyo State College of Nursing Sciences, Ibadan, Dr Gbonjubola Owolabi, has revealed.

The review was done by the state government through the Oyo State Civil Service Commission.

Recall that the National Council of Establishment (NCE) at its 43rd meeting in 2022 approved the placement of university graduate nurses on grade level 10.

At a meeting with 21 Nursing Tutors on Wednesday in Ibadan, Dr Owolabi said the state government has moved the category of nurses from grade 8, charging nursing tutors of the institution to be diligent in their duties and imbibe integrity and quality.

“The institution is out to train nursing and health practitioners and churn out quality manpower who can function effectively in community, primary, secondary, tertiary, and industrial health settings.

“I urge you to key into this vision, even as the present administration will not deprive you of your rights,” the provost stated.

Dr Owolabi, who said that the Oyo State government placed priority on integrity and quality, disclosed that “the institution has received necessary accreditations from the regulatory bodies for some courses.”

She lauded Governor Seyi Makinde for approving the promotion of the 21 tutors, saying such a gesture should be reciprocated with dedication to service.

In her vote of thanks, one of the lecturers, Mrs Abiola Elizabeth, lauded the management of the institution, saying the approval from the civil service had further accentuated the priority placed on the health sector by Oyo State government.

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Burundi Introduces Malaria Vaccine Into Routine Immunization Programme

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Malaria Deaths

By Modupe Gbadeyanka

The government of Burundi has taken a critical step towards reducing malaria cases and saving thousands of children’s lives with the introduction of the malaria vaccine into its routine immunization programme.

This followed the arrival of 544,000 doses of malaria vaccines in Burundi in January and the approval of the RTS,S malaria vaccine by ABREMA (Autorité Burundaise de Régulation des Médicaments à usage humain et des Aliments).

The inclusion of the vaccine was made possible with the collaborations of the Ministry of Health, Gavi, the Vaccine Alliance (Gavi), UNICEF, the World Health Organization (WHO), and Dalberg.

At a ceremony on Monday to announce this development, the First Lady of Burundi, Mrs Angeline Ndayishimiye, commended the organisations for supporting her husband’s government to fight malaria in the country.

Malaria remains a major public health concern in Burundi and one of the country’s top health priorities. Malaria is endemic, with two annual peaks (April-May and June) resulting in high transmission levels in some districts.

The latest data from the National Health Information System (SNIS) showed that malaria remains one of the leading causes of morbidity and mortality, with an incidence of 399.1 per 1,000 inhabitants in 2023.

Data analysis revealed that malaria accounted for 20.9 per cent of consultations in 2023 and 59.4 per cent of hospital deaths in 2021.

In Burundi, children under the age of five are the population category most vulnerable to malaria. Of the 4,857,556 malaria cases reported in 2023, children under five accounted for 2,235,481 cases, representing 46 per cent of malaria morbidity.

For this reason, as a key partner, UNICEF is committed to ensuring that every child, especially the most vulnerable, has access to this critical vaccine, alongside other essential health services, to give them a healthier start in life.

“Today marks a significant milestone as we introduce the malaria vaccine in Burundi. This initiative reflects our strong and unwavering commitment to malaria control by combining high-impact strategic interventions and our collective determination to protect our children’s lives.

“By focusing on reducing malaria mortality in children under five, we are taking a critical step towards ensuring a healthier and brighter future for the next generation. This vaccine introduction also brings us closer to a future where no child is lost to this preventable disease. We are paving the way for a malaria-free Burundi,” said Dr Lydwine Baradahana, Minister of Public Health and AIDS Prevention.

“Today, Burundi joins the list of 17 other countries on the African continent to have introduced malaria vaccine into routine immunization with Gavi support.

“Given the devastating impact of malaria, this is a development that will save thousands of young lives, offer relief to families and lessen the burden currently placed on the country’s health system,” the Senior Country Manager for Burundi at Gavi, Mario Jimenez, stated.

UNICEF Representative in Burundi, France Bégin, said, “Every child has the right to grow up healthy and protected from preventable diseases like malaria. The introduction of the malaria vaccine is a historic step, bringing new hope to families in Burundi.”

WHO representative in Burundi, Dr Xavier Crespin, remarked that, “Malaria is the leading cause of morbidity and mortality in Burundi, especially among children.

“With the measures already taken by the government such as Sulfadoxine-Pyrimethamine chemoprevention, the distribution of impregnated mosquito nets and indoor spraying, and now the introduction of malaria vaccination in children aged 6 to 18 months as recommended by the WHO,

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Oyo Enrols 10,000 Primary School Pupils for Healthcare Insurance Scheme

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Oyo primary school pupils insurance

By Modupe Gbadeyanka

About 10,000 primary school pupils have been enrolled by the Oyo State government for its healthcare insurance programme as part of efforts towards ensuring the children are of sound minds.

The beneficiaries were chosen from 90 schools across 18 local government areas of the state, and were presented their insurance scheme ID cards on Thursday at the Ibadan Civic Centre, Idi-ape, Ibadan, by the Deputy Governor, Mr Bayo Lawal.

He applauded the partnership and collaboration between the Oyo State Health Insurance Agency (OYSHIA) and the Oyo State Universal Basic Education Board (OYOSUBEB) in providing healthcare opportunities to public school children in the state.

“This scheme will ensure that our children have sound minds, while they learn in conducive environments.

“This event is a collective effort in securing a brighter future of Oyo State pupils,” the deputy governor said.

Mr Lawal also charged OYSHIA to double its efforts in extending the scheme to every school in the State, urging parents and guardians to key into the scheme.

In her goodwill message, the Chief of UNICEF in the Lagos Field Office, Ms Celine Lafoucriere, noted that the launch of the Oyo State Public Primary School Pupils Health Insurance Scheme would give access to affordable, quality healthcare; a fundamental right for every child.

“This initiative reinforces our collective commitment to universal health coverage, ensuring that no child faces financial obstacles to accessing healthcare.

“Universal health coverage is more than a healthcare goal—it’s a social and economic necessity. When children have access to healthcare, they can focus on education, grow into productive adults, break the cycle of poverty, and contribute to the success of Oyo State and Nigeria.

“This scheme exemplifies this by focusing on public primary school children, especially in hard-to-reach areas. With 90 schools already enrolled across 18 LGAs, our goal is to ensure all 33 LGAs in Oyo state are covered, leaving no child behind.

“UNICEF remains steadfast in supporting the government and communities toward universal health coverage,” she stated.

On her part, the Commissioner for Health, Dr Oluwaserimi Ajetunmobi, applauded OYSHIA and OYOSUBEB for their commitment towards healthy basic school pupils, assuring them of her Ministry’s unparalleled commitment to the scheme.

Also speaking, the Chairman of OYOSUBEB, Mr Nureni Aderemi Adeniran, applauded OYSHIA, pledging the board’s commitment to the smooth take-off and sustainability of the scheme.

“At OYOSUBEB, we operate on the principle of taking care of the pupils under our care as though they are ours,” he said, adding that the scheme would enable the beneficiaries to receive quality healthcare without paying exorbitantly to access it.

Earlier, the Executive Secretary of OYSHIA, Dr Olusola Akande, said the new door being opened today, is focusing on providing access to healthcare for 10,000 public primary school pupils in the first instance, noting that the agency will also commence an enrolment of additional 5,500 pupils into the scheme from next week.

He praised UNICEF, through whose support the agency has been able to improve on its awareness campaign and increased the communities under the Community Based Health Insurance scheme by 100 per cent.

He equally stressed the unparalleled commitment of SUBEB chairman to the scheme, stating, “His open door policy and unrestricted access ensured we were able to keep to our timeline.”

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