Health
Ghana, Malawi, Kenya to Pilot Malaria Vaccine Trial
By Dipo Olowookere
The United Nations health agency’s regional office for Africa has announced that Ghana, Kenya, and Malawi will take part in a breakthrough pilot programme to make the world’s first malaria vaccine available in selected areas, beginning in 2018.
World Health Organization (WHO) Regional Director for Africa, Matshidiso Moeti, disclosed in a press statement that, “The prospect of a malaria vaccine is great news. Information gathered in the pilot will help us make decisions on the wider use of this vaccine.”
Announcement of the coordinated rollout comes as the international community marks World Malaria Day and the kick-off of World Immunization Week, 24-30 April, which celebrates the widespread use of vaccines that protect people against 26 diseases. Overall, vaccines prevent an estimated two to three million deaths each year, according to WHO.
The injectable RTS,S vaccine was developed to protect young children from the most deadly form of malaria caused by Plasmodium parasites. It will be assessed in the pilot programme as a complementary malaria control tool to potentially be added to the core package of WHO-recommended measures for malaria prevention.
“Combined with existing malaria interventions, such a vaccine would have the potential to save tens of thousands of lives in Africa,” Dr. Moeti added.
Africa bears the greatest burden of malaria worldwide. Global efforts in the last 15 years have led to a 62 per cent reduction in malaria deaths between 2000 and 2015, yet approximately 429,000 people died of the disease in 2015 – the majority of them young children in Africa.
The WHO pilot programme will assess whether the vaccine’s protective effect in children aged 5 – 17 months old during Phase III testing can be replicated in real-life. Specifically, it will assess the feasibility of delivering the required four doses of RTS,S, the vaccine’s potential role in reducing childhood deaths and its safety in the context of routine use.
Pilot implementation strategy
The three countries selected to participate in the pilot were based on the criteria of high coverage of long-lasting insecticidal-treated nets; well-functioning malaria and immunisation programmes – a high malaria burden even after scale-up of LLINs; and participation in the Phase III RTS,S malaria vaccine trial.
Each country will decide on the districts and regions to be included, with high-malaria-burden areas prioritized, as they are predicted to provide the broadest benefit. Information garnered from the pilot will help to inform later decisions about potential wider use of the vaccine.
The malaria vaccine will be administered via intramuscular injection and delivered through routine national immunization programmes. WHO is working with the three countries to facilitate regulatory authorization of the vaccine for use in the pilots through the African Vaccine Regulatory Forum. Regulatory support will also include measures to enable the appropriate safety monitoring of the vaccine and rigorous evaluation for eventual large scale use.
Health
Mums Feel Warmth Initiative Raises Postpartum Depression Awareness
By Modupe Gbadeyanka
A transformative webinar to raise awareness on postpartum depression (PPD) by nursing mothers has been organised by MSc Media and Communication students from the School of Media and Communications of the Pan-Atlantic University.
The programme titled Beyond Baby Blues: Understanding and Overcoming Postpartum Depression was held on January 7, 2025.
It was put together by the students under the Mums Feel Warmth initiative, with experts in the field invited to speak on the matter aimed at empowering mothers and fostering a sense of reassurance.
The webinar was to highlight the journey through postpartum depression, offering a message of hope, resilience, and the importance of mental health support for mothers everywhere.
One of the speakers, Dr Laja Odunuga, who is the Care Coordinator for AVON HMO, explained the difference between the common “baby blues” and the more severe, long-lasting PPD.
The discussion highlighted how PPD can manifest not just as sadness but through severe fatigue, disconnection from the newborn, and loss of interest in activities, which can last well beyond the typical two-week period associated with baby blues.
Another expert, Ms Otomfon Ibanga, the Assistant Lead Nurse for Q-Life Family Clinic, emphasised the role of support systems, urging families and friends to be vigilant for signs of PPD and to provide a nurturing environment.
She also discussed prevention strategies, including prenatal planning for support structures and post-delivery management through therapy or medication.
On his part, Dr Chimaraoke Obialo, who is the Medical Director of Life Amada Health Consultancy, addressed the stigma surrounding PPD, advocating for education to transform societal perceptions from judgement to support.
The webinar underscored the need for community involvement, not just in recognising symptoms but in actively participating in the healing process by offering emotional and practical support.
The Mums Feel Warmth webinar was more than just an educational session; it was a call to action for society to embrace and support new mothers dealing with PPD.
By fostering open conversations and providing platforms for sharing experiences, Mums Feel Warmth continues to lead the charge against the stigma of PPD.
The commitment shown by the panellists and attendees alike promises a future where every mother has access to the understanding and care needed to navigate through the complexities of postpartum depression, ensuring that the joy of motherhood is not overshadowed by mental health challenges.
Mums Feel Warmth, with its core values of empathy, compassion, hope, community, and education, speaks to the Sustainable Development Goal 3, advocating for good health and well-being.
The initiative is breaking the silence around PPD, a condition that can significantly impact new mothers in the critical period following childbirth.
Health
NCDC Monitors HMPV Situation, Affirms Nigeria at Moderate Risk
By Adedapo Adesanya
The Nigeria Centre for Disease Control (NCDC) says the country is at “moderate” risk for Human Metapneumovirus (HMPV), a virus that leads to an upper respiratory tract infection with symptoms like cough, fever, and nasal congestion.
In a public health advisory, the Nigerian health agency said the federal government is closely monitoring the outbreak of the virus and is taking safety measures to “strengthen the country’s preparedness and response capacity”.
Recent reports indicate a significant rise in HMPV cases in China, as well as increased respiratory infections linked to HMPV in countries such as the United Kingdom (UK), France, and Germany, particularly during the winter season.
The NCDC said it conducted a risk assessment for the HMPV in collaboration with the Federal Ministry of Health and partners such as the World Health Organization (WHO), the US Centres for Disease Control and Prevention (USCDC), and the UK Health Security Agency (UKHSA).
“The assessment classified the risk of HMPV for Nigeria as moderate. This evaluation will inform and guide preparedness efforts, decision-making, and response strategies to mitigate potential impacts,” the advisory said.
It said the NCDC is working to give Nigerians “timely, accurate information and guidance to keep the Nigerian public informed and prepared”.
NCDC noted that it “in collaboration with Port Health Authorities, is taking proactive steps to ensure robust preparedness at all international points of entry (PoEs) in response to the dynamic risk assessment for Human Metapneumovirus (HMPV).
“These measures are designed to mitigate the potential risk of HMPV transmission through international travel.”
HMPV was first identified in the Netherlands in 2001 and the virus spreads through direct contact between people or when someone touches surfaces contaminated with it.
Children under two are most vulnerable to the virus alongside those with weakened immune systems such as the elderly and those with advanced cancer, according to medical experts.
There have also been worries that this could be like COVID-19, but experts have eased the fear as they are not similar because pandemics are typically caused by novel pathogens, which is not the case for HMPV.
Health
Digitising Healthcare With Local Realities in Mind: Shaping The Future of Healthcare in Africa
eHealth Africa (eHA) has urged governments and stakeholders to explore the critical factors beyond technology that are essential for the deployment of digital health solutions for the long-term success of public health systems across Africa. Data-backed interventions will help streamline operations and enable the formulation of interventions that appreciate the cultural norms when addressing the immediate needs of different communities within the region.
Speaking during a panel session at the Global Digital Health Forum 2024 in Nairobi, eHealth Africa’s Executive Director Atef Fawaz emphasised the importance of integrating technology with local cultures and addressing community-specific needs. “Understanding the unique healthcare challenges in each country allows us to deploy tech solutions that truly make an impact.”For instance, eHealth Africa successfully delivered over 5.8 million vaccines (5,801,209) to 351 primary healthcare facilities across states in Nigeria which was made possible through the deployment of the innovative Logistics Management Information System (LoMIS) application.
“The system significantly improved the availability of vaccines for Routine Immunisation (RI), ensuring timely and efficient distribution while eliminating stockouts at primary healthcare facilities. This intervention highlights our commitment to strengthening immunisation programs and enhancing healthcare delivery at the grassroots level,” he said.
In his contribution, Abdulhamid Yahaya, the Deputy Director of Global Health Informatics highlighted the need to understand the local cultural, social, and regulatory landscape to build solutions that are designed with local realities in mind.
eHealth Africa Board Member Micheline Ntiru said using technology provided stakeholders among them global health leaders, tech innovators, and development experts as well as local communities a platform to create the right solutions that work within the constraints of each community, and with the support of local leadership.
For instance, local health workers have been using mobile-based reminder systems to improve compliance and overall health outcomes while some local immunisation centres have been sending SMS reminders to parents as well as to provide educational messages about the diseases they protect against. Mobile phones, now available in nearly 80 per cent of African homes, can also be used during emergencies to dispatch mass announcements about satellite clinic locations and schedules.
According to the World Health Organisation, increased use of the Internet, email, social networking sites and availability of mobile phones facilitates the deployment of eHealth solutions, applications and services towards the improvement of national health systems. The use of technological eHealth solutions could also be used to encourage positive lifestyle changes to prevent and control common diseases.
The panel moderated by Ota Akhigbe, Director of Partnerships and Programs comprised of Ms Ntiru (Delta40 ventures), Mr Yahaya (eHealth Africa), Chief Impact Officer at Tiko – Serah Malaba, Dr Olamide Okulaja (Maisha Meds), Audere Chief Executive Officer Dr Dino Rech, and Rachel Alladian from Jacaranda. They discussed how strategic partnerships, regulatory compliance, and a deep understanding of local contexts are crucial for driving digital health innovations that can succeed in diverse regions.
The GDHF forum was attended by health scholars, researchers, and representatives from the Ministry of Health in Ethiopia, Tanzania, Kenya, Malaysia, Somalia and Sri Lanka as well as representatives from the World Bank, medicine manufacturers, technology vendors, UN agencies among others.
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