Health
Research Shows Interorganisational Deals Boost Drug Discovery, Innovation
By Adedapo Adesanya
In a recent study published in the journal Drug Discovery Today, a team of scientists at Ritsumeikan University in Japan analysed the changing trends in pharmaceutical industries to spotlight the role of interorganisational collaborations in promoting drug discovery and innovation.
Discovering new drugs has become increasingly rare for independent large pharmaceutical companies in recent times. With numbers showing that almost 60 per cent of new drugs are discovered through mergers and acquisitions and drug licensing.
Now, the university researchers shed light on the recent trends of spinouts from academia and investments in the US and Europe, foreshadowing a promising shift in the industry’s interorganisational deal networks to improve research and development productivity in the future.
“It is a challenging feat to launch a new drug in the market, given the low probability of success during the research and development (R&D) phase and the high costs involved. In recent times, industry trends in external innovation for drug discovery are rapidly changing. With an improved understanding of disease biology, decision-making can be more streamlined through the effective use of scientific information,” a statement made available to Business Post said.
Led by Associate Professor Kota Kodama of Ritsumeikan University, the team is uncovering how the trends in interorganisational deals in the pharmaceutical industry are changing to improve R&D productivity and drug discovery.
“The network structure of innovation creation in the pharmaceutical industry has changed with the increasing emergence of start-up companies spinning out from academia and research institutions as players in the source of innovation,” explains Dr Kodama, while discussing their investigations into these changing trends and the results of which were made available online on December 27, 2022, and published in volume 28 issue 3 of the journal Drug Discovery Today on March 1, 2023.
Their research suggests that the knowledge necessary for breakthrough innovation in drug discovery is more often than not obtained through alliance networks.
Over the past decade, large research-based pharmaceutical companies have used research collaborations, innovation incubators, academic centres of excellence, public-private partnerships, mergers and acquisitions (M&As), drug licensing, and corporate venture capital funds as typical methods for external innovation.
The researchers now aim to define the changes in the network structure and nature of such alliances that have occurred over the past decade to provide future strategic insights for industry and academic players involved in drug discovery.
Using data from the Cortellis Competitive Intelligence database, the researchers identified nearly 50,000 deals of various kinds related to pharmaceutical R&D across pharmaceutical, digital health software, animal drug, and medical device companies to uncover trends in the creation of new drugs for human use.
They also studied the trends of 13 of the largest pharmaceutical companies with annual revenues of more than $10 billion, who saw an improvement in their CAGR (compound annual growth rate) since 2015.
The researchers noticed that the rising CAGR correlated to a significant change in M&A-related deals after 2015, indicating that M&A-related deals drive revenue growth for large pharmaceutical companies.
Furthermore, the number of organizations involved in interorganisational deals has been increasing yearly from 2012 to 2021. Although the number of organizations involved and the number of deals may be increasing, the density of the deal networks is decreasing annually, suggesting that networks are becoming more non-cohesive.
The concentration of business relationships between organizations of certain areas in the network changed to dispersion around 2015, and new networks connecting different groups started to form after 2017.
These trends are an important illustration of how the industry landscape is gradually evolving away from the traditional network in which large pharmaceutical companies drove drug discovery output. Now, interorganisational deals among more diverse players have become active and are driving R&D productivity for startups in biotechnology and pharmaceuticals.
A clear increase in the number of academia-owned spinouts of advanced technology and expansion of investment in start-ups is a positive sign. The emergence of new chemical modalities, such as biologics, oligonucleotides, and peptides that differ from traditional small molecule drug discovery, indicate remarkable changes that have taken place over the past two decades.
The trend of increased financing for start-up companies in personalized drug development is beneficial for patent creation and will positively impact innovation creation in the coming years.
“The presence of academia to support the technologies of these start-ups is becoming very important, and government and private support and investment in this area are boosting innovation. Our study shows that such medium- and long-term support may ultimately benefit the health and well-being of humankind,” Dr Kodama noted.

Health
Chimamanda: Euracare Raises Concerns Over MDCN Investigation Panel Process
By Aduragbemi Omiyale
A Lagos-based healthcare facility currently in the limelight, Euracare Multi-Specialist Hospital, has faulted the outcome of the investigation panel of the Medical and Dental Council of Nigeria (MDCN) on the death of a 21-month-old Nkanu Nnamdi Esege, son of a renowned author, Chimamanda Ngozi Adichie.
The toddler died some weeks ago after an alleged overdose of sedative propofol, with the family alleging medical negligence.
This week, the panel suspended the two doctors of Euracare, Dr Tosin Majekodunmi and Dr Titus Ogundare.
Reacting to the development in a statement, the hospital claimed it observed “a number of serious concerns that have arisen in the course of these proceedings.”
In the statement made available to Business Post, Euracare emphasised that it vouches for the “professionalism and integrity of our clinical team,” pointing out that “certain established processes and protocols have not been followed in the manner required” during the probe.
While it empathised “with the family of Master Nkanu Nnamdi Esege” over the unfortunate incident, the healthcare firm said there was a “serious breach” by the investigators that “cannot go unaddressed.”
It identified this breach as the disclosure of “matters covered by patient and institutional confidentiality” outside the appropriate channels.
Below is the full statement from Euracare;
Our attention has been drawn to widespread media reports concerning the interim suspension orders and other findings issued by the Medical and Dental Practitioners Investigation Panel against thirteen doctors, two of whom are our clinical staff members in connection with the ongoing proceedings relating to the death of Master Nkanu Nnamdi Esege. We remain fully committed to cooperating with all relevant regulatory and judicial authorities in the course of their inquiries.
We however wish to place on record our confidence in the professionalism and integrity of our clinical team. Dr. Tosin Majekodunmi and Dr. Titus Ogundare who are experienced professionals whose records of service to patients in Nigeria span many years. Both doctors have, in their respective careers, contributed meaningfully to the delivery of quality healthcare to Nigerian patients at a standard comparable to what is obtainable in the world’s leading medical facilities.
In the interest of transparency, since the commencement of this matter, we have conducted a thorough internal review of the clinical events in question, in line with our clinical governance standards and best practices. We have actively demonstrated our commitment to transparency and will continue to engage openly with all inquiries directed at us.
We are also compelled to draw attention to a number of serious concerns that have arisen in the course of these proceedings. It is our position that certain established processes and protocols have not been followed in the manner required. We have further noted, with deep concern, that matters covered by patient and institutional confidentiality appear to have been disclosed outside the appropriate channels, and we consider this a serious breach that cannot go unaddressed.
We wish to state that we stand by the principles of equality, fairness, and good governance. Every party in this matter, including our institution and our staff, is entitled to a process that is conducted with rigour, impartiality, and respect for the rules that govern it. We will be raising these concerns through the appropriate legal and regulatory channels.
We continue to empathize with the family of Master Nkanu Nnamdi Esege. The loss of a child is a grief without measure, and we carry that awareness in everything we say and do in relation to this matter.
Health
Chimamanda: MDCN Suspends Euracare Medical Director, Anesthesiologist
By Adedapo Adesanya
The Medical and Dental Practitioners Investigation Panel of the Medical and Dental Council of Nigeria (MDCN) has invoked its order of suspension against the Medical Director of Euracare Multi-Specialist Hospital, Dr Tosin Majekodunmi, and two others, after establishing a prima facie case of medical negligence against them in the management of the late Nkanu Adichie-Esege.
Nkanu, the son of renowned Nigerian author, Chimamanda Ngozi Adichie and Dr Ivara Esege, died on January 7, 2026, after receiving care at Atlantis Hospital and undergoing medical procedures at Euracare Multi-Specialist Hospital in Lagos. He was 21 months old.
Apart from the Medical Director at Euracare, the panel also suspended the anesthesiologist at the same hospital, Dr Titus Ogundare, as well as the Chief Medical Officer at Atlantis Pediatric Hospital, Dr Atinuke Uwajeh.
The trio were suspended from medical practice in Nigeria pending the determination of their case by the Medical and Dental Practitioners Disciplinary Tribunal.
A statement signed by the committee’s secretary, Dr Enejo Abdu, also disclosed it was determining if there is a prima facie case of professional misconduct against 10 other doctors.
These are Dr Adeseye Akinsete, Dr Chidinma Ohagwu, Dr Anthony Ajeh, Dr Amarachi Bayo, and Dr Nkechi Peji. Others are Dr Olaoye Oludare, Dr Agaja Oyinkansola, Dr Patricia Akintan, Dr Babatunde Bamgboye, and Dr Raji Faidat.
The panel, which also cleared eight other doctors, reached these decisions after considering the complaint against all 21 doctors and reviewing their counter-affidavits, including their oral depositions on oath.
It concluded its investigation at its 25th session held at Excel Hotel & Resort in Abuja on February 17 and 18, 2026.
The 21-month-old child, Nkanu Adichie-Esege, was initially admitted to Atlantis Hospital in Lagos for what was described as a worsening but initially mild illness.
While arrangements were being made to transfer him to Johns Hopkins Hospital in the United States, Atlantis referred him to Euracare for pre-flight diagnostic procedures, including an MRI, lumbar puncture, and insertion of a central line.
However, the child passed following the procedures.
His parents have alleged medical negligence and professional misconduct in connection with his death.
In a legal notice dated January 10, 2026, issued by the law firm led by Kemi Pinheiro (SAN), Ms Adichie and her husband accused Euracare, its anesthesiologist, and other attending medical personnel of breaching the duty of care owed to their son.
The notice stated that the child, born on March 25, 2024, was referred to Euracare on January 6, 2026, for diagnostic and preparatory procedures ahead of an emergency medical evacuation to the United States, where a specialist team was reportedly on standby.
The procedures reportedly included: Echocardiogram, Brain MRI, and insertion of a peripherally inserted central catheter.
Lumbar puncture, Intravenous sedation using propofol was administered.
The parents alleged that the child developed sudden and severe complications while being transported to the cardiac catheterisation laboratory after the MRI.
The development has raised worries and questions about the country’s healthcare.
Health
Nigeria to Receive Breakthrough HIV Prevention Drug Lenacapavir—NACA
By Adedapo Adesanya
The National Agency for the Control of AIDS (NACA) has announced that Nigeria would take delivery of Lenacapavir, a groundbreaking human immunodeficiency virus (HIV) prevention drug that has shown 100 per cent effectiveness in preventing the viral infection in clinical trials.
A short statement released by the Head of Public Relations for NACA, Mrs Toyin Aderibigbe, on Monday said the agency had secured regulatory approval from the National Agency for Food and Drug Administration and Control (NAFDAC).
HIV over time causes acquired immunodeficiency syndrome (AIDs), a condition in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive.
Lenacapavir is an injectable treatment administered twice a year, making it a more convenient alternative to daily oral prevention drugs.
The drug is expected to be available in Nigeria and 119 other low- and middle-income countries at an affordable price of $40 per person annually, thanks to voluntary licensing agreements with generic manufacturers.
“The Government of Nigeria is advancing preparations for the introduction and rollout of Lenacapavir as Pre-Exposure Prophylaxis (PrEP).
“This is part of the government’s commitment to strengthen HIV prevention and accelerate progress toward epidemic control,” the statement read.
NACA listed some significant milestones achieved, including completion of landscape and readiness assessments across ten states: Akwa Ibom, Anambra, Benue, Cross River, Ebonyi, FCT, Gombe, Kano, Kwara, and Lagos, alongside regulatory approval by NAFDAC.
“The commodities are expected in the country in March 2026,” NACA noted.
Nigeria has approximately 1.9 million people living with HIV, with a national prevalence of 1.3% among adults aged 15-49 years.
The country recorded 74,000 new HIV infections and 51,000 AIDS-related deaths in 2021.
The South-South zone has the highest HIV prevalence at 3.1%, while women aged 15-49 years are more than twice as likely to be living with HIV as men.
Daily oral PrEP has been available in Nigeria since 2016, but uptake varies. Adherence issues like pill fatigue, stigma, limited awareness, and inconsistent access have hindered wider use.
Newer PrEP options include injections that last two or six months, providing an alternative for those who prefer less frequent dosing and may overcome many barriers of daily oral use.
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