Health
MSF Nurse Wins HIV-TB Prize for Life-Saving Test Research
By Modupe Gbadeyanka
Zimbabwean Doctors Without Borders (MSF) nurse and researcher Chenai Mathabire has won an HIV/TB Research Prize at this year’s International Aids Society Conference on HIV Science (IAS2017). Through a study conducted in Malawi and Mozambique, Chenai has provided strong evidence that an easy-to-use point-of-care TB LAM test, which quickly diagnoses tuberculosis (TB) in severely ill HIV patients, is feasible to use in real-life clinics with high numbers of HIV-TB patients.
TB is the biggest killer of people living with advanced HIV, with over 400,000 patients dying each year from the disease.
People with advanced HIV, also known as Acquired Immune Deficiency Syndrome (AIDS) have very weakened immune systems, leaving them susceptible to common infections, which can quickly become deadly.
Successfully treating ill AIDS patients involves rapidly assessing the strength of their immune systems and putting them on the right treatment straight away, whether they have TB or another disease deadly to HIV patients, cryptococcal meningitis.
However, in poorer countries, limited laboratory and X-ray facilities, and the time spent waiting on results can mean long and often deadly delays for sick patients arriving at clinics or hospitals. At the same time, people with late-stage HIV often can’t produce enough sputum for more common TB sputum tests so common tests such as sputum microscopy cannot be done. X-rays are also less useful to detect TB in people with advanced HIV.
At $3 per test, the TB LAM test offers a quick, simple and cost-effective alternative that gives on-the-spot results in 30 minutes. Yet despite being available since 2010, only 140,000 TB LAM tests are used each year.
“In Malawi, some HIV patients with suspected TB were waiting months for laboratory or X-ray results to come back. Clinicians don’t like to start patients on treatment based only on clinical signs and symptoms, they prefer to have a diagnostic test result,” says Chenai, who was responsible for implementing and supervising the study. “The TB LAM test helped them make that decision, and they felt better about starting HIV patients on TB treatment. It doesn’t replace existing tests, but adding this test helps us identify more TB cases and can improve the patients’ chances of survival.”
The test uses the HIV patient’s urine to detect LAM (Lipoarabinomanan), a protein created when TB bacteria cells break down. The lower the patients’ immunity, which is measured by numbers of CD4 T-cells, the more LAM appears in the urine and the more sensitive the test becomes. This is why the test is recommended for use in patients with CD4 cells below 100. The MSF study found the test was well accepted by staff, easy to use, and led to better, faster results than sputum or X-ray tests. Nearly 99% of TB LAM test patients received a timely result, versus 70% with sputum and 35% with X-rays.
Currently the main barrier to wider use of the TB LAM test by national governments is that it isn’t included in country guidelines and national TB programmes are not actively pushing it. Use of the TB LAM test has been recommended by the new WHO guidelines for advanced HIV for use in severely ill patients in hospitals but not yet in primary care, given the test’s decreased accuracy in patients with stronger immune responses.
MSF will use the study to advocate for health ministries in countries with high HIV TB burdens to use the TB LAM test in primary care and hospital centres, as well as include TB LAM within a diagnostic package for patients with advanced HIV. This would include point-of-care tests for CD4 (to allow rapid bed-side assessment of immune strength), cryptococcal meningitis and TB to help quick diagnosis and, most importantly, improve patients’ chances of survival.
MSF currently uses TB LAM as part of a diagnostic package in HIV projects in Democratic Republic of Congo (DRC), Guinea, Kenya, Malawi, Mozambique, Niger, Uganda and Zimbabwe. MSF currently supports over 230,000 people living with HIV on antiretrovirals in 19 countries, with a focus on free quality care, and provides free hospital-based care for people living with advanced HIV in DRC, Kenya Guinea, and Malawi.
By Modupe Gbadeyanka
The chairman of Rite Foods Limited, Mr Sulaiman Adebola Adegunwa, has been commended for donating an ultra-modern Trauma Centre to the Olabisi Onabanjo University Teaching Hospital (OOUTH) in Sagamu, Ogun State.
The facility, donated to mark his 80th birthday, is a one-stop trauma centre with all the medical equipment and healthcare personnel to handle about 2,000 trauma cases in a month, from the severe to the minor ones.
Speaking at the commissioning of the 50-bedded facility, named Sulaiman Adebola Adegunwa Trauma Centre, by the Vice President of Nigeria, Mr Kashim Shettima, on Saturday, April 5, 2025, it was stated that the centre would enhance healthcare delivery for accident victims and other trauma-related cases within Ogun and neighbouring states.
Mr Shettima noted that the provision of the healthcare facility was timely, as it aligns with President Bola Ahmed Tinubu’s agenda for upgrading the health institutions in the country.
He described the life of the donor as well lived, with significant impact in the society and immediate community, creating employment for the indigenes of Ogun State, through valuable business enterprises, like Rite Foods Limited and Ess-ay Holdings Limited, which has contributed to the growth of the state’s and national economy.
According to the VP, Mr Adegunwa has inscribed his name in gold, adding that the octogenarian believes in leaving legacies that lives for generation and this has prompted the trauma centre which will impact lives tremendously.
On his part, Governor Dapo Abiodun of Ogun State applauded the philanthropic initiative of Mr Adegunwa, saying he has demonstrated an unwavering commitment to the healthcare system of Ogun State, and that the trauma centre marks a significant milestone towards attaining that.
In her remark, the Chief Medical Director of OOUTH, Dr Oluwabunmi Fatungase, said the 50 bedded centre has been the desire of the management of the hospital, as the old 20 bedded accident and emergency centre is too small to accommodate accident victims within the state, which serves as a route for travellers traversing the different regions of the country, with a 41.5 percent accident rate.
She said it is a dream of over 20 years by various administrations come true as there is no General Hospital from Lagos to Benin and Ibadan to take care of accident victims, thereby making the trauma centre a well thought out project by Asiwaju Adegunwa.
On his part, Mr Adegunwa said, “Today, l am filled with immense joy as l reflect on Sulaiman Adebola Adegunwa Trauma Centre as another fulfilment of opportunity to serve a higher calling to give and serve.”
By Modupe Gbadeyanka
A partnership to advance high-quality patient-centred healthcare in Nigeria has been entered into between Iwosan Investments Limited and Mayo Clinic Global Consulting.
The aim is to advise and support Iwosan in delivering world-class healthcare services that will positively impact both local and regional communities.
This includes the enhancement of Iwosan’s hospital network starting with Iwosan Lagoon Hospitals and the development and integration of the Lagos Medipark Hospital.
Mayo Clinic Global Consulting will to provide strategic advice on organizational objectives and clinical practice.
Under the consulting contract, Iwosan will work with Mayo Clinic experts on several projects to advance high-quality, patient-centred healthcare in Nigeria.
Mayo Clinic is a global leader in serious and complex healthcare. Mayo Clinic Global Consulting is designed to share Mayo Clinic’s unique, comprehensive capabilities and knowledge.
The focus of this engagement is to help the Iwosan network improve administrative efficiencies and effectiveness and to enhance medical practice and patient care through the application of Mayo Clinic’s integrated clinical care and practice models.
“This marks a significant milestone in our commitment to delivering exceptional healthcare services to the people of Nigeria.
“With guidance from Mayo Clinic Global Consulting, we are confident in our ability to set new benchmarks in healthcare excellence in our region,” the chief executive of Iwosan Investments, Mrs Fola Laoye, stated.
Iwosan Investments is a healthcare investment company with an ongoing commitment to revolutionize healthcare delivery in Nigeria.
By Adedapo Adesanya
The National Agency for Food and Drug Administration and Control (NAFDAC) is increasing efforts to block the entry of substandard and counterfeit products into Nigeria, particularly from China and India, the country’s two largest pharmaceutical trade partners.
This was revealed by Mrs Mojisola Adeyeye, the Director-General of the agency, emphasised that the Clean Report of Inspection and Analysis (CRIA) scheme has significantly strengthened regulatory control over imports from these nations.
The two nation’s account for 60 per cent of Nigeria’s pharmaceutical imports and yet, there is a lot of counterfeit and substandard medicines from these countries.
She said, “Because most of these drugs come from China and India, the CRIA scheme is operational in those two countries,” adding that, “It ensures that only safe and high-quality products are shipped while preventing the export of substandard and counterfeit products.”
She note that NAFDAC has appointed and accredited CRIA agents in China and India to conduct rigorous pre-shipment inspections to tackle the issue.
In addition to appointing CRIA agents in China and India, NAFDAC is collaborating with COTECNA, a global testing, inspection, and certification service provider, to enhance quality control measures.
Mrs Adeyeye urged stakeholders to engage with these CRIA agents before shipping any consignment to Nigeria, saying, “I strongly encourage you to engage with CRIA agents before shipping any consignment–that is, to our stakeholders– from China, India, or Nigeria. You have the flexibility to choose from any of the listed CRIA agents to ensure compliance and safeguard the quality of imported products.”
NAFDAC also introduced an electronic platform, the Port Inspection Data Capture and Risk Management System (PIDCARMS), to enhance document verification and streamline inspection processes.
Mrs Adeyeye noted that CRIA agents will ensure that rejected shipments carrying drugs will not find their way to the country.
She urged stakeholders to visit NAFDAC’s official website for guidelines on product registration, labelling, and shipment requirements to ensure compliance with regulatory standards in order to prevent such lapses and ensure only approved products enter Nigeria.
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