Health
Nigeria Monitors New Strains of COVID-19, Other Diseases
By Adedapo Adesanya
The Nigeria Centre for Disease Control (NCDC) has said it is on high alert amid global concerns over new strains of COVID-19.
This was made known yesterday at a press conference in Abuja, where the health body said over 663 million confirmed cases and over 6.7 million deaths had been reported globally.
Speaking at the event, NCDC Director General, Dr Ifedayo Adetifa, said: “Globally, more than three million new cases and ten thousand deaths have been reported in the week of December 26, 2022, to January 1, 2023. This represents a reduction in weekly cases and deaths of 22 per cent and 12 per cent, respectively.
“The African Region reports a 73 per cent and 32 per cent decrease in new cases and deaths compared to the previous week.
“In the Americas and Western Pacific (including China), there has been a 74 per cent and 29 per cent increase in cases and a 49 per cent and 35 per cent increase in deaths, respectively. The increase in these countries, in part, is a component of the winter exacerbation of respiratory illness,” the DG said.
Dr Adetifa said the resurgence of COVID-19 in China, following the relaxation of the country’s zero-COVID policy and the unsurprising increase in cases, hospitalisation and deaths, also attracts concerns about the possible emergence of new variants.
He said the variants circulating in China are predominantly BA.5.2 and Bf.7. According to him, these variants have been circulating in other parts of the world, including Nigeria, since 2022.
The Omicron sub-variant, XBB.1.5, which was originally detected in New York in October 2022, is also on the increase in the US and Europe and has now been identified in more than 25 countries. The XBB.1.5 is the most transmissible form of Omicron, but it is not clear if it is more virulent than its ancestor.
The epidemiologist noted that in Nigeria, NCDC has 5,708,974 samples tested, 266,463 confirmed cases, 259,850 discharged cases and, unfortunately 3,155 deaths recorded in 36 states and the Federal Capital Territory (FCT).
He said COVID-19 has and continues to follow a different epidemiological course in Nigeria and most of Africa, with lesser cases, admissions, and deaths from the Omicron sub-lineages.
On efforts to contain the current threat, he said: “The NCDC-led COVID-19 Emergency Operation Centre (EOC) is closely monitoring the rise in the new Omicron sub-lineage, XBB.1.5, in the U.K. and U.S., and the current resurgence in China and other countries with a high volume of traffic to and from Nigeria.
“The sub-lineages partly responsible for the current increase in COVID-19 cases in other countries (XBB. 1.5 and BF.7) have not yet been detected in the country as of November 2022. We are working on completing testing and analysis for December 2022.
“Since the detection of the Omicron variant in December 2021, its sub-lineage (BQ.1/BQ.1.1) has been dominant in Nigeria.
“It is important to note that regardless of COVID-19 variants in different parts of the world, severe disease, admissions, and deaths disproportionately affect the unvaccinated and those with established risk factors, such as older people and people with co-morbidities.
“The most important action for Nigerians to take is to get vaccinated against COVID-19, as the vaccine is the most important intervention for preventing severe disease, hospitalisation, and death.
“Additionally, though COVID-19 protocols and restrictions have been eased, people at high risk for severe COVID-19 are advised to continue to adhere to recommended non-pharmaceutical intervention (NPIs), such as the use of face masks, good hand and respiratory hygiene and avoidance of crowded spaces.”
On other infectious diseases, he said: “We continue to respond to infectious diseases, including Lassa fever, Mpox, and more. To date, there are 8,202 suspected cases and 1,067 confirmed cases of Lassa fever across 27 states and 112 council areas.
“Cumulatively, from Week 1 to Week 52, 2022, 189 deaths have been reported with a case fatality rate (FR) of 17.7 per cent, which is lower than the CFR for the same period in 2021 (20.0 per cent). 72 per cent of all confirmed Lassa fever cases in 2022 were reported from three states (Ondo, Edo and Bauchi).
“Most recently, the NCDC, in collaboration with partners, federal and state stakeholders of the Technical Working Group (TWG), successfully conducted finalisation and validation of a five-year strategic plan to reduce Lassa fever fatality ratio in the country to less than ten per cent.
“We continually appeal to Nigerians to practice personal and environmental hygiene to prevent the infestation of rats in our homes and communities, especially during this dry season, which is when we typically record more cases of Lassa fever cases.”
Health
Resident Doctors Suspend Proposed Indefinite Strike
By Adedapo Adesanya
The Nigerian Association of Resident Doctors (NARD) has suspended its planned indefinite strike following the federal government’s reversal of the implementation of the reviewed Professional Allowance Table (PAT) and renewed assurances on outstanding payments.
The decision was announced in a communiqué issued at the end of an emergency National Executive Council (NEC) meeting held virtually on Saturday.
NARD had earlier resolved to embark on a total and indefinite strike over the government’s suspension of the reviewed allowance structure and other unresolved welfare concerns affecting resident doctors nationwide.
However, the association said it reconsidered its position after reviewing the outcomes of high-level engagements with key government officials and health-sector stakeholders.
According to the communiqué signed by NARD President, Dr Mohammad Usman Suleiman; Secretary-General, Dr Shuaibu Ibrahim; and Publicity and Social Secretary, Dr Abdulmajid Yahya Ibrahim, the Federal Government has now reversed its earlier decision on the allowance table.
“The NEC observed that the earlier decision to halt the implementation of the reviewed Professional Allowance Table (PAT) has been reversed, with implementation expected to reflect in the April salary and beyond,” the statement read.
The association also noted the government’s renewed commitment to settling outstanding promotion and salary arrears owed to resident doctors in affected institutions.
In addition, NARD said initial approval had been secured for the 2026 Medical Residency Training Fund (MRTF), with assurances that the disbursement process would be concluded.
“The NEC observed that the Budget Office has indicated its readiness to commence the process for the payment of the outstanding nineteen months’ arrears of the Professional Allowance,” the communiqué added.
Despite the progress, the doctors expressed concern about the continued delay in paying house officers’ salaries and called for urgent action to address the issue.
Following its deliberations, the NEC demanded the sustained implementation of the reviewed allowance structure, the prompt payment of all outstanding arrears, and the expedited disbursement of the residency training fund.
It also called for the immediate commencement of the process to clear the 19-month arrears and the convening of an urgent stakeholders’ meeting to resolve delays affecting house officers’ salaries.
“In light of the above developments, the NEC resolves to suspend the proposed total, indefinite, and comprehensive strike action, with a review of progress to be undertaken at the May Ordinary General Meeting (OGM) in Kano,” the statement said.
NARD expressed appreciation to President Bola Tinubu, Vice President Kashim Shettima, and several ministers, government agencies, and stakeholders for their interventions in resolving the dispute.
Health
Over 1.5 million Nigerian Children Living With Sickle Cell Disease—Report
By Modupe Gbadeyanka
More than 1.5 million children under the age of 15 are living with sickle cell disease in Nigeria, a new international study published in The Lancet Child & Adolescent Health, one of the world’s leading medical journals, has revealed.
In the report made available to Business Post, it was disclosed that Nigeria carries the highest burden of disease globally, far exceeding other high-burden countries such as the Democratic Republic of the Congo and Ethiopia.
The findings highlight both the scale of the challenge in Nigeria and the opportunity for the country to lead Africa in tackling one of the most preventable causes of childhood illness and death.
The study shows that nearly nine million children across sub-Saharan Africa are living with sickle cell disease in 2023, including around 1.17 million infants and 2.75 million children under five, who face the highest risk of early death without treatment.
Sickle cell disease is an inherited blood disorder present at birth. With early diagnosis and access to simple, low-cost interventions such as newborn screening, penicillin prophylaxis, routine vaccinations, malaria prevention, and hydroxyurea, most complications and deaths can be prevented.
However, in Nigeria, access to these essential services remains limited. Many children are only diagnosed after severe and avoidable complications, while others are never diagnosed at all, contributing to high levels of preventable illness and early childhood deaths.
The researchers emphasise that strengthening Nigeria’s health system response will be critical. This includes expanding newborn screening programmes, improving access to essential medicines, and integrating sickle cell care into primary healthcare services.
They called for urgent and coordinated action across government, health institutions, and development partners, including expanding newborn screening programmes, improving access to essential medicines and vaccines, and embedding sickle cell care within primary healthcare services.
The researchers, led by Professor Davies Adeloye, Professor of Public Health at Teesside University, United Kingdom, and Director of the International Society of Global Health (ISoGH), also called for increased domestic investment, supported by international partnerships, as well as stronger data systems to improve surveillance and guide policy decisions.
They concluded that even modest improvements in early-life screening and treatment in high-burden countries like Nigeria could transform child survival and significantly reduce preventable deaths.
“Nigeria now stands at the centre of the global sickle cell crisis. With over 1.5 million children affected, the scale is enormous, but so is the opportunity to act. We already know what works. Newborn screening and early treatment are effective, affordable, and can be delivered through existing health systems.
“If Nigeria prioritises sickle cell disease within its national health agenda and integrates care into routine maternal and child health services, we could save hundreds of thousands of young lives and significantly reduce avoidable deaths.” Professor Adeloye noted.
It was learned that the study analysed data from 40 studies across 22 African countries to produce the most comprehensive country-level estimates of childhood sickle cell disease to date.
Health
Helical Secures $10m Funding Package for Expansion
By Dipo Olowookere
A $10 million capital has been raised by Helical to support expansion across more top-20 pharma programmes and growth of its deployed science engineering team.
The firm will also use the money to build the compounding evidence layer that improves performance across diseases, as its mission is to make every scientist able to test hypotheses at the speed of inference and to turn in-silico discovery into a reliable engine for R&D throughput.
The funding package was from redalpine, Gradient, BoxGroup, Frst and notable angels, including Aidan Gomez (CEO Cohere), Clement Delangue (CEO HuggingFace) and Mario Goetze (pro soccer player).
Helical has a product known as the virtual AI lab for pharma, an application layer that turns biological foundation models into decision-ready, reproducible in-silico discovery workflows.
The platform has two product surfaces — the Virtual Lab for biologists and translational scientists, and the Model Factory for ML engineers and data scientists — built on the same data, the same models, and the same results.
By putting both sides in the same system, Helical closes the gap between computational predictions and biological decision-making, so teams that traditionally worked in silos can collaborate on the same evidence.
Helical was founded in early 2024. It was created by three school friends who took different paths to the same problem.
Rick Schneider built tech at Amazon and later helped the German enterprise Celonis scale in France and Japan. Maxime Allard led data science teams at IBM before pursuing a PhD focused on reinforcement learning and robotics. Mathieu Klop became a cardiologist and genomics researcher.
When bio foundation models emerged, the trio saw the chance to build the missing application layer that would let pharma teams move from model experimentation to reproducible, production discovery.
“The models alone don’t discover drugs. The system does. Pharma teams need a system that turns foundation models into workflows scientists can run, validate, and defend.
“We built Helical to make in-silico science reproducible at pharma scale, so teams can go from hypothesis to decision in days instead of months,” the co-founder of Helical, Mr Rick Schneider, said.
“We are at a unique point in time where biological foundation models and general language reasoning models are converging.
“We backed Helical because we strongly believe they have what it takes to build the pharma AI orchestration platform that will drive this transition from siloed AI models to integrated virtual AI labs,” the General Partner at redalpine, Mr Daniel Graf, stated.
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